"M" Keywords - 146 Result(s)

 M

[mechanical biocompatibility]

Novel CoCr-based superelastic metallic biomaterial with low Young's modulus

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特徴・独自性
  • General metallic biomaterials, such as stainless steels and conventional CoCr alloys, show a high Young's modulus ten times higher than that of human bones. This is an unfavored feature because it causes the so-called "stress shielding effect" when they are used as implants. β-type Ti alloys have a relatively lower Young's modulus, but they come with a compromise of low wear resistance. The current novel CoCr-based alloys are a breakthrough; they exhibit both a low Young's modulus similar to human bones and a high wear and corrosion resistance. Moreover, they exhibit superelasticity with a huge recoverable strain over 17%, also showing promise as shape memory alloys.
実用化イメージ

It is the first time that a low Young's modulus, a high corrosion and wear resistance, and a superior superelastic behavior are simultaneously obtained in a single material. The current novel CoCr-based alloys are promising for biomedical applications such as total hip or knee joint replacements, bone plates, spinal fixation devices, and vascular stents.

Researchers

Graduate School of Engineering

Xiao Xu

[Mechanical contact]

newDevelopment of a Numerical Prediction System for Sliding Part Wear and Seizure Occurrence Portions

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概要

Focusing on the lubricant film flow with phase change between the engine piston pin and connecting rod small end, we developed a new multiphase fluid-structure coupled analysis method that takes into account elastic deformation of the structure and flow path changes and developed a simulation prediction method for tribological properties under high load conditions. The simulation prediction method for tribological properties under high load conditions has been created. As a result, we succeeded in simulation prediction of the wear/seizure generating areas in sliding parts. We discovered that the peculiar deformation behavior of the components is the cause of wear/seizure.

従来技術との比較

It has been thought that computational prediction is impossible to verify the wear and seizure locations in fluid lubrication. Still, this study succeeded in the simulation prediction of wear and seizure locations in sliding parts.

特徴・独自性
  • Numerical prediction of the wear and seizure locations in the sliding parts of engine piston pins was successfully performed.
  • The bow-like deformation of the piston pin was identified as the cause of mechanical contact and seizure at the connecting rod edge.
  • A three-dimensional multiphase fluid-structure coupled analysis method has been successfully developed, considering the piston pin's elastic deformation and connecting rod and thin-film cavitation1 lubrication with unsteady flow path changes.
実用化イメージ

This research method applies to automotive engines and all sliding component elements using fluid lubrication. It contributes to damage prediction and the development of safety guidelines for transportation and industrial machinery components, enabling the optimal design of components.

Researchers

Institute of Fluid Science

Jun Ishimoto

[Mechanical Excitation Process]

Noninvasive Ultrasonic Measurement of Dynamic Properties of Heart and Arteries

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特徴・独自性
  • Complexity of the cardiac contraction sequence is still not fully understood because the dynamic mechanical excitation process, which directly correlates with contraction, cannot be accurately measured by CT, MRI, SPECT, or conventional ultrasound. By developing a noninvasive novel imaging modality with high temporal and spatial resolutions (US patent 5840028), we have detected the minute mechanical response (velocity component) to the propagation of the action potential in the human heart or to detect the propagation of the vibrations along the heart wall caused by the valve closure (Fig. 2).
  • By applying the same procedure to the human arteries, the regional change in wall thickness caused during one cardiac cycle can be measured with high spatial resolution (Fig. 1). From the measurement, the regional elasticity of tissue surrounding atherosclerotic plaque can be determined. By comparing the pathological findings with the distribution of elasticity, elasticity of lipid and that of fibrous tissue were determined. Thus, each point inside the plaque is classified into lipid or fibrous tissue using transcutaneous ultrasound (Fig. 3).
実用化イメージ

This novel method offers potential as a diagnostic technique for detection of plaque vulnerability with high spatial resolution.
We are prepared to provide academic consultations to companies interested in our research.

Researchers

Graduate School of Engineering

Hiroshi Kanai

[mechanical properties]

Multi-functionalization of composite materials by microstructure design

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特徴・独自性
  • For further social development, it is required the miniaturization, weight saving, high performance of various devices. We study on fiber, particle reinforced polymer, metal, ceramic matrices composite materials using our knowledge about materials mechanics and numerical simulation such as finite element method. We recently address to develop multi-functionalized composite materials, which have high strength, super lightweight, energy harvesting function, damage monitoring function, biodegradable at the same time.
実用化イメージ

Researchers

Graduate School of Environmental Studies

Hiroki Kurita

[mechanical property]

Advanced Control of Microstructure and Property of Structural Metallic Materials

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特徴・独自性
  • Microstructure represents various kinds of heterogeneities in the metallic materials, i.e., grains, component phase, lattice defects and chemical inhomogeneity such as impurity/alloying elements. It can be modified through control of phase transformation/precipitation and deformation/recrystallization by adjusting compositions of materials and/or through processing routes (heat treatment, deformation). Such expertise in micro/nanostructure control is very important in production of current materials from viewpoints of energy saving and recycling in structural materials such as steels and titanium alloys.
  • We attempt to apply more advanced control of micro/nanostructures, such as atomic structures of crystalline interfaces, chemistory in an atomic scale (e.g., segregation) and so on. Fundamentals of microstructure formation (thermodynamics, kinetics, crystallography) are examined both theoretically and experimentally to clarify key factors for microstructure control. Another important aspect in our research is the improvement of mechanical property by microstructure manipulation.
実用化イメージ

Possibilities to establish new functions (e.g., superplasticity, shape memory/superelasticity) as well as superior mechanical properties (e.g., ultrahigh strength with high toughness/ductility) is also explored.

Researchers

Institute for Materials Research

Tadashi Furuhara

[Mechanochemical Processing]

Powder Processing Contributing to the Global Environmental Protection

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特徴・独自性
  • Material properties and characteristics of the product as a raw material powder are dependent on the particle packing structure as well as the chemical composition. Sophisticated control of the powder processing such as mixing and grinding is strongly required. In our laboratory, we are creating the simulation method as a tool for controlling the powder processing and optimizing the powder process for achieving a resource-saving and energy-saving by the computer simulation.
実用化イメージ

We are conducting research on analysis/optimization of powder processing such as grinding, mixing, and packing by using simulation, metal recycle from urban mine through active utilization of mechanochemical effect, and generation of energy from biomass.

Researchers

Institute of Multidisciplinary Research for Advanced Materials

KANO Junya

[Mechatronics]

Robot Technology for Achieving Secure Society

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特徴・独自性
  • Tadokoro Laboratory developed ‘Active Scope Camera,' a world-unique rescue robot that can search deep in rubble piles of collapsed structures through a gap of a few cm wide. It also developed ‘Quince,' a world-unique unmanned ground vehicle that could survey the second to fifth floors of Nuclear Reactor Buildings of Fukushima-Daiichi Nuclear Power Plant. Its technologies was applied industries, including unmanned transfer vehicle for outdoors under ice and snow environment being actually used in a factory of Toyota Motor East Japan, and ‘Robo-Scope' for debris inspection in collaboration with Shimizu Corporation.
実用化イメージ

We have a policy of education through and research for solution to actual problems. Current nearly ten collaborative researches focuses on outdoor investigation, infrastructure/plant inspection, and remote/autonomous task execution by robots.

Researchers

Graduate School of Information Sciences

Satoshi Tadokoro

[Medical device]

Clinical application of pulsed jet device to achieve maximal resection of the lesion and functional preservation

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特徴・独自性
  • Maximal resection and functional preservation, are often conflicting, but are both important factors to improve patient’s quality of life. Pulsed jet system is designed to achieve this goal by removing lesions without impairing small diameter vessels (100 μm - ). Standardization and specialization of surgical procedures is expected to achieve more easily compared to conventional surgical device using pulsed jet system. We have already reported significant increase of tumor removal rate, significant reduction of intraoperative blood loss and operation time in difficult lesions in the vicinity of sella turcica and skull base through expanded transsphenoidal approach. The system can eject small amount ( - 2 μl) of high speed liquid (- 50 m/s) for minimally invasive surgery, such as endoscopic, catheter, and microscopic surgery. The system is now under stage to expand clinical application outside the field of neurosurgery, and we are expecting new collaboration who can deal with increasing safety, effectiveness, differentiation from conventional instruments, accessibility.
実用化イメージ

Researchers

Administrative Staff

Teiji Tominaga

[medical robot]

Magnetic Applications and Magnetic Materials

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特徴・独自性
  • The aim of our research are to obtain the high accuracy sensor system for the signals from the human body or electric devices and to obtain the system for approaching action to the human body by using the nano-scale controlled magnetic materials and by the development of the devices under the functions of the magnetics.
  • We studied the mechanism of obtaining the magnetic anisotropy of the magnetic thin films for the sensitive magnetic sensors. We obtained a non-metal probe for high frequency magnetic field, and confirmed the probe can measure the high frequency magnetic field with its phase information. In addition, 3D position detecting system using magnetic markers was studied to improve its position accuracy. The study about the magnetic actuator driven by the external magnetic field was carried out for biomimetic robots using the rotational magnetic field, and small wireless pumps were obtained and clarified for their application for an artificial heart-support pump.
実用化イメージ

<Medical Applications>
Motion system for capsule endoscope, Support system for endoscopic surgery, Position detecting system (motion capture), Wireless pump for artificial heart
<Sensors>
Magnetic field sensors, Strain sensors, Wireless sensors
<Materials>
Electrical steels of ultra low loss, Electrochemicaly produced materials (structure controlled in nano-scale)

Researchers

Research Institute of Electrical Communication

Kazushi Ishiyama

[medical therapy]

Development of a novel therapeutic drug, TMS-007, for acute cerebral infarction

特徴・独自性
  • The currently approved fibrynolytic therapy is only alteplase, but the use of it has been limited to 5% of patients with acute cerebral infarction due to possible side effects including hemorrhagic infarction that may be life-threatening. TMS-007 is a novel drug that has both fibrynolytic activity and brain protective effects. The aim of this project is to perform a clinical trial of this drug and to further achieve a commercial-based clinical use. We believe that this drug would contribute significantly in the treatment of acute cerebral infarction.
実用化イメージ

Researchers

Administrative Staff

Teiji Tominaga

[Medicine]

MEDICINE DETERMINATION SUPPORT SYSTEM AND MEDICINE DETERMINATION SUPPORT PROGRAM

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特徴・独自性
  • AIMS: This invention is to support the doctor’s prescription for diabetes and metabolic syndrome, especially in Japanese Clinic (Patent: JP 4176438).
  • PROBLEM TO BE SOLVED: To perform a further efficient preparation by providing information for original medicine and generic medicine in the preparation.
  • SOLUTION: The medicine price, pharmacologic effect and the like of each of original medicine and generic medicine are preliminarily recorded in a medicine database, and a generic medicine corresponding to the original medicine inputted by a doctor is automatically retrieved and displayed on a display. When the total number of the inputted medicine exceeds a number determined by insurance medical care, the generic medicine is retrieved so that the drug price of the group of the same usage is a prescribed amount or less. Welcome to your investment or co-operation.
実用化イメージ

Researchers

Cyclotron and Radioisotope Center

Katsunori Nonogaki

IVR (Interventional Radiology) Treatment of Hypertention: Minimally Invasive Treatment of Primary Aldosteronism Based on the Adrenal Vein Sampling Technology

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特徴・独自性
  • Primary aldosteronism is a leading cause of secondary hypertension accounting for approximately 10 % of hypertensive patients; 4 million patients potentially exist in Japan. We aim to optimize the method of ablating aldosterone producing adenoma using newly developed bipolar radiofrequency ablation system with 300-400kHz high-frequency current and electric power of 40W (Celon Prosurge Applicator), and establish a less invasive interventional radiological treatment of primary aldosteronism.
実用化イメージ

Collaboration with medical equipment manufacture and universities are expected to develop new devices enabling ablation of aldosterone producing adenoma. Flexible guide-wire-type ablation system and rapid aldosterone assay system should be co-developed to tread aldosterone producing microadenoma which is difficult to detect due to its small diameter of less than 5mm.

Researchers

Graduate School of Medicine

Kei Takase

Yeast models of familial Alzheimer disease to screen for gamma-secretase inhibitors and modulators

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特徴・独自性
  • Using the yeast transcriptional activator Gal4 system, we reconstituted the production of amyloid beta (Aβ), responsible for Alzheimer disease. Aβ production could be monitored by the positive growth in the selection media or by the reporter enzyme (β-Gal). Utilizing familial Alzheimer disease mutants, we established a system to screen for mutations and chemicals that modulate gamma secretase activity and reduce toxic Aβ42.
実用化イメージ

Our yeast system can be used to screen for chemicals, natural products, food ingredients, genes, and mutations that modulate γ-secretase activity and block Aβ42 production specifically. We hope to conduct collaboration research with a willing company for a practical application of this technology in industry.

Researchers

Graduate School of Agricultural Science

Eugene Futai

[MEMS]

Minimally Invasive Medical Devices and Healthcare Devices Using Micro/Nano Machining Technology

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特徴・独自性
  • Medical devices and healthcare devices which have several functions with small size have been developed using precise micromachining technology and MEMS (Microelectromechanical systems) technology. More precise and safe diagnostics and therapy, as well as novel diagnostics and treatment can be realized by developing high-functionalized endoscopes and catheters and developing novel medical devices. Healthcare without restriction of location and time is aimed by developing thin, light and high-functionalized new healthcare devices.
実用化イメージ

Besides of basic research, we are working in cooperation with clinicians and medical device companies for practical use. We founded a university-launched venture company for bridge-building between university and company and collaborative researches have been performed.

Researchers

Graduate School of Biomedical Engineering

Yoichi Haga

Hands-On Access Fabrication Facility –Open Facility for MEMS and Semiconductor Prototyping–

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概要

We offer shared facility for the development of semiconductor prototypes equipped with 4-inch, 6-inch and some 8-inch wafer fabrication tools available on an hourly basis. Know-how accumulated at Tohoku University is available, and staff provide maximum support for prototyping. The service is performed at the 1,200 m2 Super Clean Room on the second floor of the Junichi Nishizawa Memorial Research Centre at Tohoku University. For information on equipment and fees, see our website.

従来技術との比較

More than 10 experienced technical staff assist customer's usages. Standard process conditions for each process, such as etching and deposition, are provided. allowing customers to start prototyping immediately. Various materials other than silicon can also be supported.

特徴・独自性
  • We support the development of devices and semiconductor materials such as MEMS, optical elements and RF components.
  • Technical consultation on devices and processes before and during prototyping is also available.
  • A
  • 'Prototype lab' for device packaging is also available.
  • The museums where you can learn about the history of semiconductors, measuring instruments and sensors are open.
  • As part of Technology Co-creation for Semiconductor of Tohoku University, we promote R&D of semiconductors and the development of human resources.
  • On-demand semiconductor human resource development programs for students and engineers are available.
  • As a member of the MEXT's Advanced Research Infrastructure for Materials (ARIM) program, we are involved in sharing facility and data.
実用化イメージ

More than 310 companies have used our shared facility since its launch in 2010, not only from device manufacturers such as MEMS, but also from manufacturers of materials, mechanical components and equipment. To date, we have successfully supported the commercialization of about 10 devices.

Researchers

Micro System Integration Center

Kentaro Totsu

MEMS/Micromachines and Microfabrication Technology

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特徴・独自性
  • We are studying MEMS (Micro Electro Mechanical Systems) and related technologies, which are typically used for the input/output of information/communication devices, the safety of automobiles etc. Our representative topics include integrated sensors, piezoelectric devices, RF MEMS, micro energy devices and wafer-level packages. Our facilities are open-accessible and well equipped with a lot of tools for lithography, dry/wet etching, thin film deposition, wafer bonding, device mounting and evaluations, which can be operated by each researcher. Using these tools, a variety of MEMS are being prototyped. Also, new microfabrication tools are being developed by ourselves.
実用化イメージ

We are collaborating with many companies, from which visiting researchers are dispatched to our laboratory. We also accept companies which want to just use specific tools in our facilities. Consultation is always welcome.

Researchers

Graduate School of Engineering

Shuji Tanaka

Design, fabrication and test of high performance miniaturized sensor and actuator systems

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特徴・独自性
  • Micro and nano electro-mechanical systems (MEMS/NEMS) have completely changed human society in the past decades. Many devices that are taken for granted these days like smart phone, future car and drone would be unthinkable without them.
  • The integration of various new kinds of materials, such as metallic glass and nanostructures into micro technologies allows us to create devices with novel performance and characteristics; examples include acoustic sensors and actuators, thermoelectric generators and wafer level packages.
  • In collaboration with partners inside and outside Tohoku University, technologies are being developed that can be transferred to industry ranging from material integration and processes to packaging and reliability.
実用化イメージ

Wide collaboration in Microsystem technology is possible. We develop, implement and optimize processes, devices and systems until they are ready for use, keeping in mind reliability, yield and other important features for commercialization. We work with also with partners, such as Fraunhofer. Flexible interlinking of expertise and capacities with other research groups enables us to meet broad project requirements and create complex system solutions.

Researchers

Micro System Integration Center

Froemel Joerg Eckhardt

[Message relay]

Message Transmission without Cellular Coverage, “Relay-by-Smartphone"

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特徴・独自性
  • Our technology provides the necessary method for sending messages even when the physical infrastructure is not available. The technology utilizes common smartphone WiFi functionality to send message in a multi-hop fashion. Thus it is possible to send message to people further away. Our technology has been designed to be based on Delay-Tolerant Networks (DTN), but the technical key idea is the combination of DTN and Mobile Adhoc Network (MANET), which can improve the message delivery in an area with high population density or where mobility are fixed such as evacuation center.
実用化イメージ

This technology can be used to distribute information during emergency situation such as after disaster. In addition, it is possible to provide additional services such as advertisement within shopping areas, distribution of coupons, exchange of information within small group during public events or uses as transceiver during group hiking. There is also possibility of using this technology to provide communications service in developing nations.

Researchers

Graduate School of Information Sciences

Nei Kato

[meta material]

Development of Renewable Energy Systems for Sustainable Development Society

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特徴・独自性
  • Development of renewable energy systems as well as research on high efficient energy conversion systems is a key technology to solve the global-scale environmental destruction and energy problems. We are working on the research on the advanced technology of renewable energy such as solar energy and hydrogen. Topics of research are two of the following roughly separately. 
(1) Development of highly effective thermal energy systems and energy saving systems by using spectral control of thermal radiation. 
(2) Aiming at the achievement of the hydrogen energy society, we develop new energy conversion devices based on solid state ionics, and perform feasible studies for solid oxide fuel cells (SOFCs) based on mechanics of materials.
実用化イメージ

High temperature solar absorption materials
High effieciency solar-termophotovoltaic (STPV) system
Small power source for mobile electric devices based on micro-SOFC
New energy harvesting devices in harsh environment

Researchers

Graduate School of Engineering

Hiroo Yugami