Tohoku University. Research Profiles

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Development of the next generation anti-HIV agents

update:2018-12-28
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HIV infection is one of most serious concern in infectious diseases. We will perform anti-HIV assays for unmet medical needs in control of HIV infections with established novel assays by us. We have developed reverse transcriptase inhibitor that has novel mechanism of inhibition, translocation-inhibition (J Biol Chem, 2009). Dr Kodama participated in the primary screening and development of a new HIV integrase inhibitor, elvitegravir (J Virol 2009), which phase III clinical trials by the Gilead Sciences will complete, soon. We have a representative resistant HIV strain-library for anti-HIV screening and several target oriented high through-put screening systems.


Researchers

International Research Institute of Disaster Science

KODAMA, Eiichi , Professor
MD, PhD

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