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Establishment of Minimally Invasive Cell Therapy for Diabetes by Introducing Interdisciplinary Approach

update:2018-12-18
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Features
The islet transplantation is the ideal "minimum invasive" cell transplant therapy for the severe diabetic patients who are suffering with controlling the blood glucose levels. In this project, we try to have a cross organization among the advanced technologies in islet transplantation as one of the typical cases. Our chief objective is to construct the center of medical cell-engineering therapy as successful examples in Tohoku University. We are convinced that technical innovation through this project could contribute much more to the activation of medical industry based upon cell therapy.

Targeted Application(s)/Industry
We have already established effective academic-industrial alliances regarding our several projects including a development of new type of cell-isolation enzyme. However, we are still looking for possible candidates concerning a special device for cell transplantation and medical grade-pathogen free animals.

Researchers

Graduate School of Medicine

GOTO, Masafumi , Professor
Doctor of Medicine

Keywords

Related Information

Patents
WO2010/0587072 FUSION COLLAGENASE IN WHICH AFFINITY TAG IS LINKED AND METHOD FOR PRODUCING THE SAME

2007-169261 Evaluation method for isolated islet grafts

Publications
Synergistic effect of neutral protease and clostripain on pancreatic islet isolation( Transplantation 2015:99(7):1349-1355)

A novel resting strategy for improving islet engraftment in the liver(Transplantation 2014:97(3):280-286)

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