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Ceramic Microspheres for Intra-Arterial Radiotherapy of Cancer

update:2018-12-13
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Features
We developed ceramic microspheres around 25 µm in diameter containing yttrium and/or phosphorus for intra-arterial radiotherapy of deep-seated cancer. The microspheres are activated to β-emitter by neutron bombardment. When radioactive microspheres are injected into a target organ, they are trapped inside small blood vessels in the tumor, blocking the nutritional supply to the tumor and delivering a large, localized dose of short-range, highly ionizing β-rays.

Targeted Application(s)/Industry
Our microspheres are useful for minimally invasive treatment of inoperable deep-seated cancer, especially liver cancer. We want to advance our research for clinical application in collaboration with drug manufacturer and/or medical device company.

Researchers

Graduate School of Biomedical Engineering

KAWASHITA, Masakazu , Associate Professor
PhD

Keywords

Related Information

Publication
Scientific paper:Preparation of ceramic microspheres for in situ radiotherapy of deep-seated cancer [Biomaterials, 24, 2003, 2955-2963]
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