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Method for efficient production of induced pluripotent stem cells utilizing cells derived from oral mucosa

update:2019-03-12
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We provide a technique which can produce induced pluripotent stem (iPS) cells with high establishment efficiency and imposes lower burden on patients. iPS cells can be produced efficiently with significantly increased establishment efficiency by selecting cells derived from the oral mucosa and introducing a reprogramming factor, which can induce the reprogramming of the cells into pluripotent stem cells, into the cells.

Researchers

Graduate School of Dentistry Division of Molecular and Regenerative Prosthodontics

EGUSA, Hiroshi , Professor
D.D.S., Ph.D.

Keywords

Related Information

Publication
Egusa H, Okita K, Kayashima H, Yu G, Fukuyasu S, Saeki M, Matsumoto T, Yamanaka S, Yatani H: Gingival fibroblasts as a promising source of induced pluripotent stem cells. PLoS One, 5(9): e12743, 2010.
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