"M" Keywords - 146 Result(s)

 M

[Metabolic analyzer]

INSTRUMENT AND METHOD FOR ANALYZING METABOLIC CONDITION OF LIVING BODY AND RECORDING MEDIUM

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特徴・独自性
  • AIMS: The invention is to analyze metabolic condition, especially in oxygen consumption and energy production in the adipose tissues of human (Patent: JP 3848818).
  • PROBLEM TO BE SOLVED: To provide an instrument and method for analyzing the metabolism condition of a living body which is constructed in such a manner that it can measure the metabolism condition of a living body correctly and easily, and a recording medium.
  • SOLUTION: A metabolism condition analyzer is provided with an input means for inputting information about the body of a subject, a control means for processing this information and an output means for outputting results of the processing. The information consists of name, age, sex, race, height, weight, bioelectric resistance value and the date and time of measurement. A data file consisting the control means stores evaluation data of a metabolic condition which is previously determined by medical judgment based on a combination of an internal respiration index and oxygen consumption and energy production in adipose tissues. These are computed by calculating the value obtained by subtracting one from a body density calculated from the height, weight of the subject and the bioelectric resistance value and then multiplying the value. Welcome to your investment or co-operation.
実用化イメージ

Researchers

Cyclotron and Radioisotope Center

Katsunori Nonogaki

[Metabolic syndrome]

MEDICINE DETERMINATION SUPPORT SYSTEM AND MEDICINE DETERMINATION SUPPORT PROGRAM

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特徴・独自性
  • AIMS: This invention is to support the doctor’s prescription for diabetes and metabolic syndrome, especially in Japanese Clinic (Patent: JP 4176438).
  • PROBLEM TO BE SOLVED: To perform a further efficient preparation by providing information for original medicine and generic medicine in the preparation.
  • SOLUTION: The medicine price, pharmacologic effect and the like of each of original medicine and generic medicine are preliminarily recorded in a medicine database, and a generic medicine corresponding to the original medicine inputted by a doctor is automatically retrieved and displayed on a display. When the total number of the inputted medicine exceeds a number determined by insurance medical care, the generic medicine is retrieved so that the drug price of the group of the same usage is a prescribed amount or less. Welcome to your investment or co-operation.
実用化イメージ

Researchers

Cyclotron and Radioisotope Center

Katsunori Nonogaki

Exercising "Cultured" Myotubes!

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特徴・独自性
  • We succeeded in generating highly developed cultured C2C12 myotubes by manipulating intracellular Ca2+ transients with electric pulse stimulation (EPS), that are endowed with similar properties to in vivo skeletal muscle in terms of (1) excitation-induced contractile activity as a result of de novo sarcomere formation, (2) higher energy expenditure (as assessed by AMPK activation), and (3) improved insulin responsiveness (as assessed by exofacial myc-GLUT4 translocation assay).
実用化イメージ

Taking advantage of our “in vitro Exercise Model", our innovation will be an excellent alternative for the animal experimentation that can be applicable for a wide array of skeletal muscle research including drug screen.

Researchers

Graduate School of Biomedical Engineering

Makoto Kanzaki

[Metabolism]

Skeletal Regulation of Energy Metabolism

特徴・独自性
  • This project studies the influence of bone on energy metabolism in the body through health and disease.
実用化イメージ

This project may come up with new tools for metabolic syndrome prediction, therapy and diagnosis .

Researchers

Frontier Research Institute for Interdisciplinary Sciences

Aseel Mahmoud Suleiman Marahleh

[Metabolomics]

Oral Biofilm Functional Analysis: from “What Are They?" to “What Are They Doing?"

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特徴・独自性
  • A large number of microorganisms inhabit the oral cavity, such as the teeth, gingiva and tongue, in the form of oral biofilm. The oral cavity forms an ecosystem where the host (humans) and parasites (microorganisms) coexist. Disruption of the balance of this oral ecosystem leads to dental caries, periodontal diseases and oral malodor, and even deterioration of dental materials.
  • Using leading-edge techniques of anaerobic experimental systems including original and unique devices, as well as the notion of "omics" such as metagenomics and metabolomics, we conduct research on oral biofilm functions. Knowledge of oral biofilms, from "what are they?" to "what are they doing?", enables us to address their control, that is, prevention of and therapy for oral biofilm-associated diseases.
実用化イメージ

Risk assessment of oral biofilm-associated diseases, such as dental caries, periodontal disease, oral malodor and aspiration pneumonia
Effects of medicine and food ingredients on oral biofilm function
Evaluation of biofilm-mediated material deterioration

Researchers

Graduate School of Dentistry

Nobuhiro Takahashi

[metal]

Advanced Control of Microstructure and Property of Structural Metallic Materials

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特徴・独自性
  • Microstructure represents various kinds of heterogeneities in the metallic materials, i.e., grains, component phase, lattice defects and chemical inhomogeneity such as impurity/alloying elements. It can be modified through control of phase transformation/precipitation and deformation/recrystallization by adjusting compositions of materials and/or through processing routes (heat treatment, deformation). Such expertise in micro/nanostructure control is very important in production of current materials from viewpoints of energy saving and recycling in structural materials such as steels and titanium alloys.
  • We attempt to apply more advanced control of micro/nanostructures, such as atomic structures of crystalline interfaces, chemistory in an atomic scale (e.g., segregation) and so on. Fundamentals of microstructure formation (thermodynamics, kinetics, crystallography) are examined both theoretically and experimentally to clarify key factors for microstructure control. Another important aspect in our research is the improvement of mechanical property by microstructure manipulation.
実用化イメージ

Possibilities to establish new functions (e.g., superplasticity, shape memory/superelasticity) as well as superior mechanical properties (e.g., ultrahigh strength with high toughness/ductility) is also explored.

Researchers

Institute for Materials Research

Tadashi Furuhara

[metal complex]

Metal complex catalysts for energy devices

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特徴・独自性
  • We have developed a new catalyst for fuel cells and metal-air batteries with using metal azaphthalocyanine unimolecular layer (AZUL) adsorbed on carbon materials. We applied it to variety of applications in the field of energy conversion and next generation energy devices.
実用化イメージ

Industries relating with energy and mobilities.

Researchers

Advanced Institute for Materials Research

Hiroshi Yabu

[Metal components]

Additive Manufacturing of Metallic Parts with Electron Beam Melting (EBM)

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特徴・独自性
  • Electron beam melting (EBM) is a type of additive manufacturing technologies. EBM uses electron beam as an energy source to melt metal powder and produce metal thin layers. This sequence is repeated in a layer-by-layer manner to fabricate three-dimensional (3D) components.
  • This technology can produce any kinds of structures based on 3D CAD models and is suitable for custom-made manufacturing.
  • In addition, our recent studies revealed that the unique microstructure, such as directional solidification and uniform dispersions of fine precipitates, are obtained by EBM; this technology is useful to realize advanced materials that cannot be obtained conventional manufacturing.
実用化イメージ

The EBM technology has received much attention for producing metal parts used in biomedical, aerospace and automotive industries.
Rapid prototyping / rapid tooling is one of the applications of this technology.

Researchers

New Industry Creation Hatchery Center

Akihiko Chiba

[metal films]

Room temperature bonding using thin metal films (Atomic Diffusion Bonding)

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特徴・独自性
  • Atomic diffusion bonding of two flat wafers with thin metal films is a promising process to achieve wafer bonding at room temperature. High surface energies of metal films and a large atomic diffusion coefficient at the grain boundaries and film surfaces enable bonding at room temperature without unusually high loading pressure. This technique, which enables bonding of any mirror-polished wafer, is gaining wider use for fabricating optical and electrical devices. Moreover, bonding of mirror polished metals and polymer sheets can be achieved, which further extends the application of this bonding technique.
実用化イメージ

Optical, power and electrical devices, MEMS, bonding of polymer sheets, metals, and ceramics for precision mechanical equipments.

Researchers

Frontier Research Institute for Interdisciplinary Sciences

Takehito Shimatsu

[Metal nano-particles]

Microwave Processing of Functional Inorganic Materials

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特徴・独自性
  • Microwave processing is one of the attractive fields in recent materials processing. We perform various materials processing using non-equilibrium reaction field induced by microwave and/or ultrasonic irradiation. The topic contains powder metallurgy, nitride coatings, synthesis of new functional materials, fabrication of nanoparticles, etc. Recently we have developed a new TiN coating method using our microwave irradiation equipment operated at a frequency of 2.45 GHz. The method is simple but applicable to various substrates with complex shape. This method can be applied to various nitride coatings and will open a new coating technology in many fields of applications.
実用化イメージ

The major targets of TiN coatings are for cutting tools, ball bearings, dental implants, die and mold for stamping, and ornaments. The newly developed method makes it possible to perform nitride coatings within a short time using a standard microwave heating equipment. We hope to conduct collaborative research with a willing company for a practical application of these technology.

Researchers

Administrative Staff

Hirotsugu Takizawa

[Metal-air battery]

Metal complex catalysts for energy devices

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特徴・独自性
  • We have developed a new catalyst for fuel cells and metal-air batteries with using metal azaphthalocyanine unimolecular layer (AZUL) adsorbed on carbon materials. We applied it to variety of applications in the field of energy conversion and next generation energy devices.
実用化イメージ

Industries relating with energy and mobilities.

Researchers

Advanced Institute for Materials Research

Hiroshi Yabu

Bio-inspired engineering for energy and biological applications

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特徴・独自性
  • Our goal is "bio-inspired engineering" to create new functions that exhibit functions beyond the nature systems by learning from their superior functions and incorporating them into creating materials and devices. For example, the development of surface treatment and adhesives learned from mussels, the development of anti-biofouling substrates learned from pitcher plants, the design of non-platinum catalysts for highly active fuel cells (hydrogen, enzymes, microbes, etc.) learned from hemoglobin, and needle-type biosensors learned from biological needles.
実用化イメージ

Based on electrochemistry and polymer chemistry, I provide technologies and expertise in the energy, biotechnology, and electrical and electronic fields, including metal-air batteries, fuel cells, surface treatment, adhesion, biosensors, etc.

Researchers

Frontier Research Institute for Interdisciplinary Sciences

Hiroya Abe

[metallic glass]

Design, fabrication and test of high performance miniaturized sensor and actuator systems

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特徴・独自性
  • Micro and nano electro-mechanical systems (MEMS/NEMS) have completely changed human society in the past decades. Many devices that are taken for granted these days like smart phone, future car and drone would be unthinkable without them.
  • The integration of various new kinds of materials, such as metallic glass and nanostructures into micro technologies allows us to create devices with novel performance and characteristics; examples include acoustic sensors and actuators, thermoelectric generators and wafer level packages.
  • In collaboration with partners inside and outside Tohoku University, technologies are being developed that can be transferred to industry ranging from material integration and processes to packaging and reliability.
実用化イメージ

Wide collaboration in Microsystem technology is possible. We develop, implement and optimize processes, devices and systems until they are ready for use, keeping in mind reliability, yield and other important features for commercialization. We work with also with partners, such as Fraunhofer. Flexible interlinking of expertise and capacities with other research groups enables us to meet broad project requirements and create complex system solutions.

Researchers

Micro System Integration Center

Froemel Joerg Eckhardt

[Metallurgy]

Eco-Material Processing

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特徴・独自性
  • The major subject of our group is ferrous process metallurgy including thermodynamics of metals, alloys and molten slags, high temperature heterogeneous kinetics, phase equilibria of complex oxide systems and so on. We are interested in physic-chemical fundamentals of processing of metals, slags, scrap and waste. Recently our research interests are extended to multidisciplinary area so-called "Industrial Ecology" by the combination of process metallurgy, LCA (life cycle assessment) and social science such as econometrics.
実用化イメージ

Typically our research group is aggressively working in the area of material flow analysis of critical metals considering the quality of recycled materials. Currently our major research partners are steel and non-ferrous industries, while we do hope to collaborate with waste treatment company, mineral industry and an administrative organ.

Researchers

New Industry Creation Hatchery Center

Tetsuya Nagasaka

[Metalorganic vapor phase epitaxy (MOVPE)]

R&D in Semiconductor Materials and their Device Applications Bringing System Evolutions

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特徴・独自性
  • 1. Development of Distributed Feedback (DFB) Laser Diodes (LD) widely used in optical communications systems realizing a highly information-based society. This LD increases the transmission capacity by 25,000 times per fiber which means the bit rate of 10Tb/s.
  • 2. Nitride semiconductors famous for blue light emitting diodes.
  • (a) Proposal of InGaAlN system considering device applications in 1989
  • (b) Success in growth of single crystalline InGaN by metalorganic vapor phase epitaxy (MOVPE) in 1989
  • (c) Prediction of band-gap energy (Eg) of InN much smaller than the values reported in 1980s and its   experimental confirmation in 2002
  • (d) Observation of photoluminescence from InGaN in 1991
  • (e) Prediction of phase separation in InGaAlN in 1997
実用化イメージ

DFB-LD: Fabrication of periodic structure with submicron scale, Epitaxial growth of semiconductor films on the substrate with fine structures, LD fabrication process, device evaluation, and device simulation

Nitride Semiconductors: MOVPE growth, N-polar growth, Evaluation of semiconductor materials, Fabrication of light-emitting devices, solar cells, and high-power transistors

Researchers

New Industry Creation Hatchery Center

Takashi Matsuoka

[metamaterials]

Development of Miniature and Highly-Functional Photonic Devices Using Ultrafine Microstructures

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特徴・独自性
  • In our laboratory, miniature and highly-functional photonic devices based on new optical phenomena caused by the interaction of ultrafine microstructures with light have been studied. In addition, development of new production technology to overcome the problems that have been obvious from the practical application viewpoint of nanophotonic devices has been performed.
    • -Main research topics--
    MEMS tunable metamaterials for optical control.
  • Structural color filters using subwavelength gratings for the applications of display and spectroscopic analyzers.
  • Surface-smoothing technology using surface self-diffusion.
  • Study of low loss silicon nanophotonic devices.
実用化イメージ

We aim to realize optical filters, optical resonators, and color filters, by using above technologies. Also, development of nano-photonic elements fabricated by a nanoimprint technology has been progressed.
We hope to conduct collaborative research with a willing company for a practical application of this technology in industry.

Researchers

Graduate School of Engineering

Yoshiaki Kanamori

[MgO]

newGlass that conducts heat well

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概要

We aim to give high thermal conductivity to glass, which is known as a material that does not conduct heat well, and to apply it to new fields.

従来技術との比較

If mixed with a high thermal conductive material, glass can be a good conductor of heat. However, all the advantages of glass, such as transparency and freedom of molding, are lost. In this research, we succeeded in developing a transparent glass with high thermal conductivity that retains its glassiness by adopting the strategies of high thermal conductivity MgO deposition and refractive index matching.

特徴・独自性
  • Transparent
  • Free molding
  • Thermal conductivity ~ 3 W/(m K) [300% of that of window glass]
実用化イメージ

Heat dissipation management using glass [heat dissipating glass substrates, lenses, fibers, etc.]

Researchers

Graduate School of Engineering

Nobuaki Terakado

[Micro energy]

MEMS/Micromachines and Microfabrication Technology

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特徴・独自性
  • We are studying MEMS (Micro Electro Mechanical Systems) and related technologies, which are typically used for the input/output of information/communication devices, the safety of automobiles etc. Our representative topics include integrated sensors, piezoelectric devices, RF MEMS, micro energy devices and wafer-level packages. Our facilities are open-accessible and well equipped with a lot of tools for lithography, dry/wet etching, thin film deposition, wafer bonding, device mounting and evaluations, which can be operated by each researcher. Using these tools, a variety of MEMS are being prototyped. Also, new microfabrication tools are being developed by ourselves.
実用化イメージ

We are collaborating with many companies, from which visiting researchers are dispatched to our laboratory. We also accept companies which want to just use specific tools in our facilities. Consultation is always welcome.

Researchers

Graduate School of Engineering

Shuji Tanaka

[micro machine]

Magnetic Applications and Magnetic Materials

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特徴・独自性
  • The aim of our research are to obtain the high accuracy sensor system for the signals from the human body or electric devices and to obtain the system for approaching action to the human body by using the nano-scale controlled magnetic materials and by the development of the devices under the functions of the magnetics.
  • We studied the mechanism of obtaining the magnetic anisotropy of the magnetic thin films for the sensitive magnetic sensors. We obtained a non-metal probe for high frequency magnetic field, and confirmed the probe can measure the high frequency magnetic field with its phase information. In addition, 3D position detecting system using magnetic markers was studied to improve its position accuracy. The study about the magnetic actuator driven by the external magnetic field was carried out for biomimetic robots using the rotational magnetic field, and small wireless pumps were obtained and clarified for their application for an artificial heart-support pump.
実用化イメージ

<Medical Applications>
Motion system for capsule endoscope, Support system for endoscopic surgery, Position detecting system (motion capture), Wireless pump for artificial heart
<Sensors>
Magnetic field sensors, Strain sensors, Wireless sensors
<Materials>
Electrical steels of ultra low loss, Electrochemicaly produced materials (structure controlled in nano-scale)

Researchers

Research Institute of Electrical Communication

Kazushi Ishiyama

[micro vessle]

Visualization of Biological Microstructure with High Frequency Ultrasound and Photoacoustic Imaging

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特徴・独自性
  • "Features"
  • High-resolution imaging of biological tissue is non-invasively obtained with high frequency ultrasound. We have developed some ultrasound microscope systems which realized the resolution of 15-micron with 100 MHz and resolution to visualize a single cell with GHz range ultrasound. Ultrasonic imaging provides not only tissue morphology but also information on tissue elasticity. Recently, we have developed a real-time three-dimensional photoacoustic imaging system for visualization of subcutaneous micro vasculature and oxygen saturation.
  • "Targeted Application(s)/Industry"
  • High frequency ultrasound and photoacoustic imaging is repeatedly and non-invasively applied for early diagnosis of atherosclerosis, skin aging and tissue metabolism. They are useful for efficacy assessment of cosmetics and pharmaceuticals. High frequency ultrasound is also applied in the industrial areas where thickness measurement of opaque film or bilayer thin coating with the precision of 0.1 micron is required.
実用化イメージ

Researchers

Graduate School of Biomedical Engineering

Yoshifumi Saijo