Tohoku University. Research Profiles

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Exploration of Innate Immune Regulators

update:2018-12-19
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Features
Innate immunity is the first line of defense against infectious microorganisms, and the basic mechanisms of this process, including pathogen recognition and immune response activation, are evolutionarily conserved. To screen pharmaceuticals that target innate immunity, we established an ex vivo culture system based on the innate immune response of Drosophila, which is highly useful for identifying immune regulators that act on human innate immunity. We use this system to search for compounds that regulate innate immunity.

Targeted Application(s)/Industry
Innate immunity is a good target for the development of immune regulators to suppress unwanted immune responses, such as septic shock, inflammatory diseases and autoimmunity.

Researchers

Graduate School of Pharmaceutical Sciences

KIKUCHI, Haruhisa , Associate Professor

Keywords

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