Tohoku University. Research Profiles


Fabrication of The Novel Designed Nanodrugs Composed of Poorly Water-Soluble Compounds



One of our major research focuses is to design the novel drug nanoparticles, so called “Nano-prodrugs”, and to apply them as anticancer drugs or eye drops with excellent delivery efficiency. Nano-prodrugs are constructed by synthetic prodrugs molecules which contains poorly water-soluble substituent. They could be fabricated to nanoparticles with 100 nm or less in size by our reprecipitation technique, which has been used to create organic nanomaterials. We are aiming at practical application of our Nano-prodrugs in the near future.

Targeted Application(s)/Industry

Our reprecipitation technique for fabricating organic nanomaterials is a versatile technique that can be applied to various organic molecules as well as drug compounds. We hope to conduct collaborative research with a willing company on controlling and evaluating properties of the organic nanoparticles.


Institute of Multidisciplinary Research for Advanced Materials

KASAI Hitoshi , Professor
Doctor of Science