Prevention and amelioration of late-onset hypogonadism by food ingredients
update:2022-06-30
We developed screening system of functional ingredients from food extracts for anti-LOH using testis-derived cells, and clarified that vitamins, nutraceuticals, and edible plant extracts have potentiating activities for the production of testosterone.
Researchers
Graduate School of Agricultural Science
SHIRAKAWA Hitoshi
, Professor
Doctor of Agricultural Science
Keywords
Related Information
Horigome S, Maeda M, Ho H.-J, Shirakawa H, Komai M. Effect of Kaempferia parviflora extract and its polymethoxyflavonoid components on testosterone production in mouse testis-derived tumour cells. J. Funct. Food., 2016, 26, 529-538.
Ho H-J, Shirakawa H, Yoshida R, Ito A, Maeda M, Goto T, Komai M. Geranylgeraniol enhances testosterone production via cAMP/protein kinase A pathway in testis-derived tumor I-10 cells. Biosci. Biotechnol. Biochem., 2016, 80, 791-797.
Ito A, Shirakawa H, Takumi N, Minegishi Y, Ohashi A, Howlader ZH, Ohsaki Y, Sato T, Goto T, Komai M. Menaquinone-4 enhances testosterone production in rats and testis-derived tumor cells. Lipids Health Dis., 2011, 10, 158.
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