Tohoku University. Research Profiles

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"B" Theme - 12 Result(s)

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Bio-Hybrid MEMS for Medical, Environmental and Food Engineering

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Features

We have developed original manufacturing techniques for bio-hybrid MEMSs that utilize special functions of bio-elements, proteins and living cells, for molecular selective sensing and power generation from natural fuels.
(1) Conducting polymer electrodes printed on hydrogels (image 1)
(2) Dynamic control of bio-adhesion by electrochemical means (image 2)
(3) Micro Biofuel Cells with flexible enzyme electrode patches (image 3)

Targeted Application(s)/Industry

We hope to conduct collaborative research with a willing company for a practical application of these technologies in industry.

Department of Bioengineering and Robotics, Graduate School of Engineering
NISHIZAWA Matsuhiko, Professor Doctor of Engineering

Biological Application of Scanning Probe Microscope

Features

We have invented a unique method to non-invasively evaluate the quality of individual mammalian embryos based on oxygen consumption. A Pt microelectrode was scanned near the single embryo sample to obtain oxygen concentration profile. Respiration activity of single embryo was estimated based on spherical diffusion theory. Further, it was found that the respiration activities of individual embryos corresponded the developmental potential of the embryos. Independently, we have developed a procedure of mRNA quantification from single-cell based on SPM featuring multi-functional probes. Next, we are going to combine the two methods mentioned above for quality control of mammalian embryos and embryonic stem cells.

Targeted Application(s)/Industry

Our methods will be applied for assisted reprodictive technoloy (ART), pancreatic islet transplantation, or animal breeding.

Graduate School of Engineering
SHIKU Hitoshi, Professor Doctor of Engineering

Biomarker Development and Preemptive Therapy of Alzheimer's Disease

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Features

Over the past 20 years, our understanding of molecular pathology of dementia and AD has dramatically deepened, and new biomarkers including amyloid PET and cerebrospinal fluid (CSF) amyloid42/tau as well as therapeutic strategies have been developed. However, clinical trials of disease-modifying drugs in mild to moderate AD were unsuccessful or were halted due to serious adverse drug effects.

Targeted Application(s)/Industry

These results strongly suggest that disease-modifying therapies should be started much earlier before a widespread neuron death will occur. We hope that early detection and prevention with preemptive therapy may lead to a success of fighting AD.

Department of Geriatrics and Gerontology, Institute of Development, Aging and Cancer
ARAI Hiroyuki, Professor MD, PhD

Biometric Monitor and Therapeutic Apparatus System Mounted Inside Mouth

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Features

We propose the biometric monitor and therapeutic apparatus system with telemedicine, especially for the elderly and patients with chronic diseases. This system is consisted of the sensor probes gathering biometric information and daily living activities, the signal processing units with wireless telecommunication with telemedicine center, and the therapeutic operation units with drug delivery into the mouth.

Targeted Application(s)/Industry

This system is embedded in usual dental prosthesis, such as denture or mouthpiece, so that this system can be installed into the mouth with no sense of discomfort. The system provides the necessary means of health support in an aging society, especially for the elderly who live alone and the hospital inpatients.

Graduate School of Dentistry
KOSEKI Takeyoshi, Professor PhD

Biomodel for Development of Endovascular Treatment

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Features

We perform in-vitro or computational researches for development of medical devices. We develop a model of artery or bone to evaluate medical devices. And we apply optimization way for development of medical devices. Our main target is, currently, stent, or catheter.

Targeted Application(s)/Industry

Our collaboration company can be; medical equipment, device, medical image, MEMS, standardization, medical training, or polymer.

Institute of Fluid Science
OHTA Makoto, Professor Doctor of Engineering

Blockchain-based Approachs for High Secure P2P-type Decentralized Cloud Storage and Practical Smart Contract for Trading Personal Data

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Features

We are developing a decentralized P2P (Peer to Peer) type cloud storage that realizes innovative level of security by use of surplus storages of P2P nodes with the Blockchain technology. The developed storage can avoid the risk of large-scale information leakage of stored data due to the weakness of the central server. By using our cryptographic currency for rewards and usage fees in the storage, fair storage usage of all users can also be achieved.
In addition, We are developing a unique smart contract technology for practical decentralized trading of personal data among an unspecified number of users.

Targeted Application(s)/Industry

We hope to conduct collaborative researches with companies developing Bitcoin 2.0 type application (e.g. smart contract, Fintech) based on the Blockchain technology, the Internet of Things (IoT) technology, Medical Database for practical use.

Center for Information Technology in Education
SAKAI Masao, Associate Professor Doctor of Engineering

Brain Development and Aging Using Large Brain MRI Database

Features

We have revealed relationships among brain structure, brain function, lifestyle, genetic factor, and cognitive function using brain magnetic resonance imaging (MRI) database. The goal of our project is to prevent several diseases and disorders such as dementia by performing personalized medicine using the large brain MRI database.

Targeted Application(s)/Industry

Our research is related with several industrial fields such as food, sleep, and other lifestyle industries. In addition, our research is also related with medical field such as preventing medicine and brain check-up.

Institute of Development, Aging and Cancer
TAKI Yasuyuki, Professor Ph.D.

Brain Mechanism Realizing Human Mind

Features

I am investigating the brain mechanism of human mind. Specifically, my target is the internal schema that dissociate the self and other in the following three layers: physical, interpersonal, and social domains.

Targeted Application(s)/Industry

  • Improvement of the interface of the system
  • Clarifying the neuro-cognitive mechanism of the effect on the customer
  • New concept of the customer satisfaction
  • Institute of Development, Aging and Cancer
    SUGIURA Motoaki, Professor MD PhD

Brain Science-Based Preventive Care and Rehabilitation for Dementia in Communities

Features

1. To produce the brain science-based evidence for dementia prevention using neuropsychological tests and neuroimaging methods (amyloid PET etc.)
2. To establish the evidence-based integrated community care system including early detection, preventive care, and rehabilitation for dementia.
3. To apply for early screening of the " weakness due to disaster" by considering the measure for dementia is similar to that for the weakness.

Targeted Application(s)/Industry

An industry-academic cooperation is expected with insurance companies, industries for producing screening device, program for preventive care and rehabilitation.

Division of Geriatric Behavioral Neurology, Cyclotron and Radioisotope Center
MEGURO Ken-ichi, Professor MD, PhD

Brainmorphic Computing Hardware

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Features

We will develop a brainmorphic computing hardware, which realizes the brain-specific functions such as conscious/sub-conscious process, self, selective attention, and so on, by directly using inherent physics and dynamics of constituent devices. The resulting hardware would be small, efficient, high-performance. Some examples include the chaotic neural network reservoir, optimization through high-dimensional complex dynamics, and neural network composed of spin-orbit torque nano-devices.
The resulting hardware is suitable for the edge AI which learns users’ personal behavior. Examples include watching service devices embedded in hearing aids or dental implants, which monitor and learn personal cardiac and brain-wave signals or saliva ingredients, to detect abnormal situations.

Targeted Application(s)/Industry

Edge AI devices, especially for peri-personal space), Time-series processing (prediction, recognition, and categorization), Online real-time learning.

Research Institute of Electrical Communication
HORIO Yoshihiko, Professor Ph.D

Business Administration and Corporate Social Responsibility

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Features

My research areas are primarily business ethics, nonprofit organization (NPO) and business and society. I have explored these fields in epistemological, ethical, or managerial approaches from various theoretical points of view. Some of themes that I study now are on how companies should recognize ethical issues on a cognitive formed framework or how companies should create a dialogue between the company and stakeholders (consumers and employees, etc.) through PL (product liability) or labor litigation process.

Targeted Application(s)/Industry

I have also experiences in engaging with a domestic manufacturer in developing their PL cases and training programs as well as stating third-party opinions in CSR reports issued by a local power company. I am willing to give you any knowledge of these areas.

Graduate School of Economics and Management
TAKAURA Yasunari, Associate Professor Master of Commerce

Business Continuity Management (BCM)

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Features

Business continuity management (BCM) is a strategy of a company or a public organization to continue critical operations or recover them early even when they suffer serious damage from disasters, major accidents, terrorism, infectious diseases and so on. The plans for BCM is called BCPs. Japanese government and industry organizations actively promote introduction and improvement of BCM. My laboratory have studied how to spread and improve BCM. I participate in development of governmental guidelines for BCM. I also operate a BCM study group consist of companies, governmental organizations and research institutes in Sendai City.

Targeted Application(s)/Industry

I would be able to give an advice to companies or organizations which are going to introduce or improve their BCM and BCP at the request of them. In addition, collaboration with corporate groups can be assumed to promote or improve BCM practically.

International Research Institute of Disaster Science
MARUYA Hiroaki, Professor Doctor(Economics)