Tohoku University. Research Profiles

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"M" Theme - 20 Result(s)

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Magnetic Applications and Magnetic Materials

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Features

The aim of our research are to obtain the high accuracy sensor system for the signals from the human body or electric devices and to obtain the system for approaching action to the human body by using the nano-scale controlled magnetic materials and by the development of the devices under the functions of the magnetics.
We studied the mechanism of obtaining the magnetic anisotropy of the magnetic thin films for the sensitive magnetic sensors. We obtained a non-metal probe for high frequency magnetic field, and confirmed the probe can measure the high frequency magnetic field with its phase information. In addition, 3D position detecting system using magnetic markers was studied to improve its position accuracy. The study about the magnetic actuator driven by the external magnetic field was carried out for biomimetic robots using the rotational magnetic field, and small wireless pumps were obtained and clarified for their application for an artificial heart-support pump.

Targeted Application(s)/Industry

<Medical Applications>
Motion system for capsule endoscope, Support system for endoscopic surgery, Position detecting system (motion capture), Wireless pump for artificial heart
<Sensors>
Magnetic field sensors, Strain sensors, Wireless sensors
<Materials>
Electrical steels of ultra low loss, Electrochemicaly produced materials (structure controlled in nano-scale)

Research Institute of Electrical Communication
ISHIYAMA Kazushi, Professor Doctor of Engineering

Magnetic Materials (Permanent Magnets, High Frequency Materials, Microwave Absorbers)

Features

The objectives of my researches are the development of high performance magnets and improvement of their magnetic properties. I have already developed following high performance magnets, such as Nd-Fe-B magnets using didymium, Sm-Fe-N high coercive powders prepared by HDDR and Fe-Cr-Co magnets. Recently, I have studied about the reduction of Dy content in Nd-Fe-B magnets for the use of HEV and have succeeded to develop high coercive Dy-free Nd-Fe-B sintered magnets by decreasing the grain size. I have also developed new kinds of microwave absorbers for the use in the frequencies of GHz range using permanent magnetic materials or nanoparticles.

Targeted Application(s)/Industry

High performance magnetic materials can be used in many applications in automobile, home electronics, IT and medical industries. We hope to conduct collaborative researches with companies producing magnetic materials for the use in these applications, which aims to improve magnetic properties or to develop new magnetic materials.

Department of Materials Science, Graduate School of Engineering
SUGIMOTO Satoshi, Professor Doctor of Engineering

Material Design for Solution of Energy and Environmental Problems by Multi-Physics and Multi-Scale Simulation

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In order to solve the energy and environmental problems, the development of the high-functional and high-performance materials is required in a wide variety of research fields such as fuel cell, Li-ion battery, tribology etc. Especially, the recent material technologies constitute of multi-physics and multi-scale phenomena including chemical reaction, friction, impact, stress, fluid, photon, electron, heat, electric and magnetic fields etc. on nano- and macro-scales. Therefore, Kubo laboratory is pioneering the development of multi-physics and multi-scale simulator on the basis of quantum chemistry and is utilizing K supercomputer for realizing the theoretical material design with high-accuracy.

Targeted Application(s)/Industry

We utilize our developed multi-physics and multi-scale simulation technology on the basis of quantum chemistry for acceelerating the material development in a wide variety of private companies of automotive, machinery, power, electronics, material, metal, chemistry etc. and then contribute to solving the energy and environmental problems.

Institute for Materials Research
KUBO Momoji, Professor Doctor of Engineering

Mathematical Biology

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Principal subject of our study is the mathematical model analysis to make clear or present the point at issue for scientific discussion about real biological/social phenomena, or to promote the advanced theoretical research: what theoretical problem about target phenomenon is treated, how the problem is mathematically modeled, what mathematical analysis is applied for the model, and how the mathematical result is lead to the discussion in biological/social science.

Targeted Application(s)/Industry

Graduate School of Information Sciences
SENO Hiromi, Professor Doctor of Science

Measurement-Integrated Simulation to Analyze Complex Flows

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In order to obtain huge fluid information of real flows we are developing a new flow analysis methodology "measurement-integrated simulation" by integrating experimental measurement and computer simulation. Complex real flows are accurately reproduced by the effect of a feedback signal to compensate the difference between the measurement and calculation. This can be appliedto wide variety of complex flow problems, for example, real-time visualization of blood flows for medical diagnosis, flow analysis around automobile body, real-time monitoring of flow in a complex piping in a nuclear power plant.
We are prepared to provide academic consultations to companies interested in our research.

Institute of Fluid Science
HAYASE Toshiyuki, Professor Doctor of Engineering

Mechanism of Restoration and Rehabilitative Treatment of Movement Disorders

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Our investigation aims to develop rehabilitative treatment for movement disorders due to brain damage using non-invasive brain stimulation (NIBS) such as transcranial magnetic stimulation (TMS), and transcranial direct current stimulation (tDCS). TMS, eddy current stimulation, and tDCS (1-5 mA, 10 minutes) both can modulate excitability of the cerebral cortex, and are applicable for restoration of limb paresis. We focus on modulating body scheme to induce appropriate adaptive changes of the central nervous system using NIBS.

Targeted Application(s)/Industry

Our goal is to develop therapeutic systems for movement disorders in which NIBS devices are combined with robotics or sensors. We would like to collaborate with companies for developing, manufacturing, and selling innovative medical devices.

Department of Physical Medicine and Rehabilitation, Graduate School of Biomedical Engineering
IZUMI Shin-ichi, Professor PhD

MEDICINE DETERMINATION SUPPORT SYSTEM AND MEDICINE DETERMINATION SUPPORT PROGRAM

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AIMS: This invention is to support the doctor’s prescription for diabetes and metabolic syndrome, especially in Japanese Clinic (Patent: JP 4176438).
PROBLEM TO BE SOLVED: To perform a further efficient preparation by providing information for original medicine and generic medicine in the preparation.
SOLUTION: The medicine price, pharmacologic effect and the like of each of original medicine and generic medicine are preliminarily recorded in a medicine database, and a generic medicine corresponding to the original medicine inputted by a doctor is automatically retrieved and displayed on a display. When the total number of the inputted medicine exceeds a number determined by insurance medical care, the generic medicine is retrieved so that the drug price of the group of the same usage is a prescribed amount or less. Welcome to your investment or co-operation.

Department of Diabetes Technology, Graduate School of Biomedical Engineering
NONOGAKI Katsunori, Professor MD, PhD

MEMS/Micromachines and Microfabrication Technology

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We are studying MEMS (Micro Electro Mechanical Systems) and related technologies, which are typically used for the input/output of information/communication devices, the safety of automobiles etc. Our representative topics include integrated sensors, piezoelectric devices, RF MEMS, micro energy devices and wafer-level packages. Our facilities are open-accessible and well equipped with a lot of tools for lithography, dry/wet etching, thin film deposition, wafer bonding, device mounting and evaluations, which can be operated by each researcher. Using these tools, a variety of MEMS are being prototyped. Also, new microfabrication tools are being developed by ourselves.

Targeted Application(s)/Industry

We are collaborating with many companies, from which visiting researchers are dispatched to our laboratory. We also accept companies which want to just use specific tools in our facilities. Consultation is always welcome.

Department of Bioengineering and Robotics, Graduate School of Engineering
TANAKA Shuji, Professor Doctor of Engineering

Message Transmission without Cellular Coverage, “Relay-by-Smartphone"

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Our technology provides the necessary method for sending messages even when the physical infrastructure is not available. The technology utilizes common smartphone WiFi functionality to send message in a multi-hop fashion. Thus it is possible to send message to people further away. Our technology has been designed to be based on Delay-Tolerant Networks (DTN), but the technical key idea is the combination of DTN and Mobile Adhoc Network (MANET), which can improve the message delivery in an area with high population density or where mobility are fixed such as evacuation center.

Targeted Application(s)/Industry

This technology can be used to distribute information during emergency situation such as after disaster. In addition, it is possible to provide additional services such as advertisement within shopping areas, distribution of coupons, exchange of information within small group during public events or uses as transceiver during group hiking. There is also possibility of using this technology to provide communications service in developing nations.

Graduate School of Information Sciences
KATO Nei, Professor Doctor of Engineering

Method for efficient production of induced pluripotent stem cells utilizing cells derived from oral mucosa

Features

We provide a technique which can produce induced pluripotent stem (iPS) cells with high establishment efficiency and imposes lower burden on patients. iPS cells can be produced efficiently with significantly increased establishment efficiency by selecting cells derived from the oral mucosa and introducing a reprogramming factor, which can induce the reprogramming of the cells into pluripotent stem cells, into the cells.

Targeted Application(s)/Industry

Graduate School of Dentistry Division of Molecular and Regenerative Prosthodontics
EGUSA Hiroshi, Professor D.D.S., Ph.D.

Methods to Restore Strelity of Gramineous Plants under High- and Low-Temperature Stress Conditions

Features

Plant reproductive development is more sensitive than vegetative growth to many environmental stresses. High-temperature injury is becoming an increasingly serious problem due to recent global warming. In wheat, barley, and other crops, the early phase of anther development is most susceptible to high temperature. Oppositely, grain yields in rice plants are often reduced by exposure to low temperature. Unexpected climate change, such as abnormally hot or cool summer temperatures, have occurred repeatedly during recent years. This method indicates that an appropriate use of specific phytohormones, such as auxin and GA, may promote stress tolerance and adaptation to abiotic stresses.

Targeted Application(s)/Industry

These potentially novel functions of the classical phytohormones will be important sustainable agriculture in the face of global climate change.

Graduate School of Life Sciences
HIGASHITANI Atsushi, Professor Doctor of Science

Microwave Processing of Functional Inorganic Materials

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Microwave processing is one of the attractive fields in recent materials processing. We perform various materials processing using non-equilibrium reaction field induced by microwave and/or ultrasonic irradiation. The topic contains powder metallurgy, nitride coatings, synthesis of new functional materials, fabrication of nanoparticles, etc. Recently we have developed a new TiN coating method using our microwave irradiation equipment operated at a frequency of 2.45 GHz. The method is simple but applicable to various substrates with complex shape. This method can be applied to various nitride coatings and will open a new coating technology in many fields of applications.

Targeted Application(s)/Industry

The major targets of TiN coatings are for cutting tools, ball bearings, dental implants, die and mold for stamping, and ornaments. The newly developed method makes it possible to perform nitride coatings within a short time using a standard microwave heating equipment. We hope to conduct collaborative research with a willing company for a practical application of these technology.

Department of Applied Chemistry, Graduate School of Engineering
TAKIZAWA Hirotsugu, Professor Doctor of Engineering

Minimally Invasive Medical Devices and Healthcare Devices Using Micro/Nano Machining Technology

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Medical devices and healthcare devices which have several functions with small size have been developed using precise micromachining technology and MEMS (Microelectromechanical systems) technology. More precise and safe diagnostics and therapy, as well as novel diagnostics and treatment can be realized by developing high-functionalized endoscopes and catheters and developing novel medical devices. Healthcare without restriction of location and time is aimed by developing thin, light and high-functionalized new healthcare devices.

Targeted Application(s)/Industry

Besides of basic research, we are working in cooperation with clinicians and medical device companies for practical use. We founded a university-launched venture company for bridge-building between university and company and collaborative researches have been performed.

Graduate School of Biomedical Engineering
HAGA Yoichi, Professor Doctor of Medicine, Doctor of Engineering

Molecular Dynamics Analysis of Coating and Surface Modification

Features

Molecular-scale mechanism of solid-liquid affinity, wettability, thermal boundary resistance and molecular deposition are analyzed by molecular dynamics simulations toward its control. With a background of heat and mass transport and interfacial thermodynamics, transport phenomena of various scales ranging from spin coating of photoresist to SAM (self-assembled monolayer) and hydrophobic/hydrophilic treatment by attaching some molecular basis are studied. Futhermore, the molecular-scale mechanisms which determine thermophysical properties and the molecular structure that realizes desired thermophysical properties are studied. We can conduct effective collaboration and provide academic consultations to companies interested in our research.

Institute of Fluid Science
OHARA Taku, Professor Doctor of Engineering

Molecular Imaging from Basic Research to Clinical Application

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Molecular Imaging and its Application to Drug Development: Positron emission tomography (PET) comprises the administration of carbon-11- or fluorine-18-labeled tracers to human subjects in order to describe the concentration-time profile in body tissues targeted for treatment. As PET involves the administration of only microgram amounts of unlabeled drug, the potential risk to human subjects is very limited. Consequently, required preclinical safety testing is reduced as compared to conventional human studies.

Targeted Application(s)/Industry

PET molecular imaging studies are gaining increasing importance in clinical drug research, as they have the potential to shorten time-lines and cut costs along the critical path of drug development. We have developed several PET tracers for molecular imaging such as amyloid imaging and central nervous system drug research at Tohoku University, Japan. We will present the recent progress and strategy of "PET molecular imaging" in order to accelerate drug development.

Department of Pharmacology, Graduate School of Medicine, and Cyclotron and Radioisotope Center
YANAI Kazuhiko, Professor MD., PhD

Molecular studies on new resources for hybrid rice breeding

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F1 hybrid breeding is one of the most advanced techniques for production of cultivars with higher yield and desirable traits of both parents. Most of hybrid rice utilize cytoplasmic male sterility (CMS) and fertility restoration system. We develop a Tohoku University-original CW-type CMS and fertility restorer line and study their molecular mechanism. The CW-type cytoplasm enables indica rice cultivars to be CMS, which could not be achieved by other known cytoplasm.

Targeted Application(s)/Industry

Hybrid rice has an average 30% yield advantage over inbred lines, and is cultivated on 13% of the world rice fields. Our study provides a new and original resource for hybrid rice breeding for globalization of rice industry.

Graduate School of Agricultural Science
TORIYAMA Kinya, Professor Doctor of Agriculture

Monomer-Recycle System of Biodegradable Plastics by Industrial Fungal Fermentation and Application of Fungal Biosurfactant Proteins to Nanoparticles for Medical Use

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In Japan, solid-phase fungal fermentation systems using the industrial fungus Aspergillus oryzae have been extensively used for producing fermented foods such as soy sauce and sake; the annual production volume of the products is over one million tons. The efficient enzymatic hydrolyzing systems are expected to be applicable to biological recycling of biodegradable plastics. We found that A. oryzae can effectively degrade polybutylene succinate-coadipate (PBSA) by the combination with an esterase (cutinase) CutL1 and novel surfactant proteins, RolA and HsbA that are attached to the surface of PBSA and then recruit CutL1. The recruitment of Cutl1 by the surfactants stimulated PBSA degradation.

Targeted Application(s)/Industry

The fungal biosurfactant protein is applicable to industrial recycling of biodegradable plastics and to production of immune-response free nano-particles for medical use.

Graduate School of Agricultural Science
ABE Keietsu, Professor Doctor of Agriculture

Morphology Control of Alloy Nanoparticles by Restrict Controlling of Metal Complex

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To apply the specific properties of nano materials for the industrial products, various technologies, such as synthesis method for single phase alloy nanoparticles which shows the effective activity for aimed reaction, that for well crystallized alloy nanoparticles which shows the resistively against for undesirable reaction, and that for single layered surface control method, etc, is developed by precise control of metal complexes in the solution by using the calculation and various research equipment including the photon factory.

Targeted Application(s)/Industry

Our technology can be useful for various industry which need the restrict control of surface properties, such as catalysts and electronics.

Graduate school of Environmental studies
TAKAHASHI Hideyuki, Professor Doctor of Engineering

Multi-functionalization of composite materials by microstructure design

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For further social development, it is required the miniaturization, weight saving, high performance of various devices. We study on fiber, particle reinforced polymer, metal, ceramic matrices composite materials using our knowledge about materials mechanics and numerical simulation such as finite element method. We recently address to develop multi-functionalized composite materials, which have high strength, super lightweight, energy harvesting function, damage monitoring function, biodegradable at the same time.

Targeted Application(s)/Industry

Department of Materials Processing, Graduate School of Engineering
KURITA Hiroki, Assistant Professor Doctor of Engineering