"N" Theme - 15 Result(s)
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Nano-Precision Mechanical Manufacturing for Extreme OpticsFeaturesThrough the fusion of technology and manufacturing techniques, the level of Japanese manufacturing has come to be regarded as exceptional. In order to survive in the current economic climate, research and development work in manufacturing processing technology must be promoted in order to develop ultra-high-precision mechanical manufacturing technologies capable of producing structures having three-dimensional shapes with ultra-smooth surfaces and extremely precise form accuracy, as well as ultra-high-precision lithography technologies that will enable the creation of nano structures by adding and subtracting atoms or molecules with precise control. In our laboratory, we focus on the creation and development of new manufacturing principles and technologies for nano-precision mechanical manufacturing. Graduate School of Biomedical Engineering
KURIYAGAWA Tsunemoto, Professor
PhD (Engineering)
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Nano-Scale Total-Analysis Based on TEMFeaturesOur lab develops accurate nanometer scale characterization methods of crystal structures by convergent-beam electron diffraction (<strong>CBED</strong>) and electronic structures by electron energy-loss spectroscopy (EELS) and soft-X-ray emission spectroscopy (<strong>SXES</strong>) for evaluating new functional materials. For performing crystal structure studies, we developed a new Ω-filter electron microscope and a refinement soft-ware, which can perform not only atom positions but also electrostatic potential and charge distributions. For electronic structure studies, a high-resolution EELS microscope and SXES instruments were developed. Targeted Application(s)/IndustryCollaborated research of Local structures (symmetry, polarity, lattice defects) by CBED and electronic structures (bandgap, dielectric property and chemical state) by EELS and SXES on semiconductors, metals and dielectric materials are acceptable. Instructions of those analysis methods are also acceptable. Institute of Multidisciplinary Research for Advanced Materials
TERAUCHI Masami, Professor
Doctor of Science
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Nanoparticle synthesis by femtosecond laser pulsesFeaturesBy using femtosecond laser pulses, nanoparticles of noble metals (gold, platinum, silver, palladium etc.) are synthesized. Particles with the size of a few nanometers are fabricated by simply irradiating metal ion solution with the laser pulses. This process needs no reducing agent and is able to synthesize alloy nanoparticles of noble metals. The collection of nanoparticles is easy because the process is performed in liquid. We are prepared to provide academic consultations to companies interested in our research. Targeted Application(s)/IndustryInstitute of Multidisciplinary Research for Advanced Materials
SATO Shunichi, Professor
Doctor of Engineering
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Natural Language Processing for Semantic Analysis of Big DataFeaturesThis lab conducts fundamental research for deep natural language processing (NLP) and NLP-oriented information organization such as classification, extraction, and summarization of language information. Our activities also cover a broad range of applied research including NLP-based information and knowledge mining, information credibility analysis, and resilient ICT through the maximal use of Big Data. Targeted Application(s)/Industry(i) Analysis of market trend or research trend through intelligent text mining, (ii) Discovery of potential needs and risks from opinions in social media, (iii) Management of knowledge in a company by analyzing internal documents, etc. |
Network Roaming System with Flexible Access ControlFeaturesThe laboratory works on development of authentication wireless LAN systems which refer user attribute to realize flexible access control capability.Improvement and evaluation of new access control is devised based on experience of operation of an international wireless lan roaming service ‘eduroam' which is based on 802.1x authorization protocol. Targeted Application(s)/IndustryThe development contains application of OpenFlow technology to select a connecting network depending on user affiliation, as well as access control based on pre-defined attribute information. |
Neutron scattering study on macroscopic quantum phenomenaFeaturesIn contrast to other scattering techniques, such as x-ray and electron diffractions, neutron scattering has the following advantages: 1) light atoms, such as H and Li, can be detected; 2) electron spins can be detected; 3) low energy excitations can be investigated. Using the neutron scattering technique, we search for macroscopic quantum phenomena in many-body electron systems, such as macroscopic singlet ground states in the quantum frustrated magnets and spin-fluctuation-mediated unconventional superconductors. Targeted Application(s)/IndustryAs noted above, neutron scattering can be used for investigating magnetic structure, spin dynamics, light atom positions in crystalline materials and their dynamics. Hence, this technique is very useful when those pieces of information are to be known. Institute of Multidisciplinary Research for Advanced Materials
SATO Taku J, Professor
Doctor of Science
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New Developments in Bone Regenerative TherapyFeaturesOctacalcium phosphate/collagen composites (OCP/Col: BonarcⓇ), a bone regenerative material commercialized in 2019, outperforms the bone regeneration of existing bone substitutes and is cost-effective and easy to use. Recently, we have demonstrated that the addition of teriparatide (TPTD: a parathyroid hormone for the treatment of osteoporosis) to OCP/Col, or improvements in the manufacturing process of OCP/Col, would expand their use for intractable bone defects and bone augmentation, which is difficult to treat. Targeted Application(s)/IndustryAs a medical devise of bone regenerative material, expansion of application in various bone defect (orthopedic surgery, neurosurgery, etc.) and overseas expansion would be expected. Furthermore, as a combination product based on OCP/Col would provide a therapeutic alternative for difficult bone defects or urgent surgery. Bone Regenerative Engineering Laboratory, Regenerative and Biomedical Engineering Division, Graduate School of Biomedical Engineering
KAMAKURA Shinji, Professor
Doctor of Dental Science
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New High-Throughput, High Resolution DNA Methylation Analysis Method, PCR-Luminex for the Diagnosis of Genomic Imprinting Disorders in ART BabiesFeaturesThe parent-of–origin specific expression of the imprinted genes relies on DNA methylation acquired during gametogenesis. Recent studies indicate the possibility of excess imprinting disease occurrence in babies conceived by assisted reproductive technologies (ART). PCR-Luminex method is powerful tool for the methylation analyses, suitable for the use at the clinical diagnosis level because of taking much time and multistep procedures. Targeted Application(s)/IndustryWe have developed a new high-throughput, high resolution DNA methylation analysis method. PCT international patent was performed. Environment and Genome Research Center, Graduate School of Medicine
ARIMA Takahiro, Professor
Medical Doctor
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Next-generation Technology Development of High-efficient Utilization of Valuable ElementsFeaturesPractical materials and devices are changed by the times. Their performances of the materials are generally improved by utilizing valuable elements. In the next generation, it is required that novel materials and devices are developed, whereas it appears that the quality of minerals and raw materials is degraded. We are taking several initiatives of research and development of high-efficient utilization of valuable elements. Targeted Application(s)/IndustryWe are promoting sound industry-academia collaboration by providing reliable research results and a number of true knowledge to many people based on the research achievements we have built up to now, and also by notifying related information. |
Noninvasive Ultrasonic Measurement of Dynamic Properties of Heart and ArteriesFeaturesComplexity of the cardiac contraction sequence is still not fully understood because the dynamic mechanical excitation process, which directly correlates with contraction, cannot be accurately measured by CT, MRI, SPECT, or conventional ultrasound. By developing a noninvasive novel imaging modality with high temporal and spatial resolutions (US patent 5840028), we have detected the minute mechanical response (velocity component) to the propagation of the action potential in the human heart or to detect the propagation of the vibrations along the heart wall caused by the valve closure (Fig. 2). Targeted Application(s)/IndustryThis novel method offers potential as a diagnostic technique for detection of plaque vulnerability with high spatial resolution. Department of Electronic Engineering, Graduate School of Engineering
KANAI Hiroshi, Professor
PhD
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Nonlinear Aeroelastic and Multibody Dynamic Analysis for Floating Wind Turbine and Next-Generation AircraftFeaturesFloating wind turbine and next-generation aircraft have high-aspect-ratio blade and wing that undergo nonlinear aeroelastic deformation. We have developed a nonlinear aeroelastic analysis framework with absolute nodal coordinate formulation (ANCF). This nonlinear aeroelastic deformation is coupled with multibody dynamics. We are also developing a novel analysis framework for this coupling dynamics. Targeted Application(s)/IndustryDynamic, aeroelastic, structural, vibration, aerodynamic analyses for Aeroelastic Multibody Systems: Tohoku University, Department of Aerospace Engineering, Space Structures Laboratory
OTSUKA Keisuke, Assistant Professor
PhD
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Nonprofit Organizations and Social CapitalFeaturesNonprofit organizations strive to solve community and social problems and to create new social values. Nonprofit organizations have the role to create citizenship and social capital - trust, norms and networks - in community. Social capital, an invisible and soft capital has increasingly become important to a sustainable management of an organization. Graduate School of Economics and Management
NISHIDE Yuko, Professor
Doctor of International Public Policy
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Novel Cu-Based Shape Memory Alloy with High DuctilityFeaturesRecently, we have developed a novel Cu-Al-Mn based shape memory alloy with high SM properties and with a ductility twice higher than that in Nitinol . Furthermore, this novel SM alloy needs no die for the shape setting and is fabricated with relatively low cost. Very recently, we have successfully developed a device to cure ingrown toenail by using this SM alloy. Targeted Application(s)/IndustryVery recently, we established a fabrication process for the Cu-Al-Mn sheet, wire and bar with 0.1 - 20mm in thickness or diameter. We hope to conduct collaborative research with a willing company for a practical application with this new SM alloy. Department of Materials Science, Graduate School of Engineering
KAINUMA Ryosuke, Professor
Doctor of Engineering
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Novel high-throughput screening systems for new antibiotics targeting bacterial virulence factorsFeaturesChemotherapy toward bacterial infection, which dates back to the discovery of penicillin, opened up the golden era of antibiotics. Thereafter, various clinically important antibiotics were introduced into the clinic, and hence serious bacterial infectious diseases were eradicated. However, this ephemeral hope has been disappearing due to the emergence of antibiotic resistant pathogens toward every new antibiotics launched into the clinic, such as multidrug-resistant Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus (MRSA). To combat these life-threatening pathogens, there is a pressing need to develop new antibiotics. However, new antibiotics discovered in the future will be nullified by development of resistance to these antibiotics, since their targets are essential for bacterial survival. From this aspect in which inhibitors of the essential functions inevitably select resistant mutants, bacterial virulence could be a fascinating target for developing new antibiotics, because virulence attenuators are thought to be less likely to generate resistance. We focus on a novel protein translocation system, Tat, since this system appears to be involved in several aspects of bacterial virulence and is not present in mammalian cells, and iron-metabolism-associated system as novel targets for development of their inhibitors. We hope to conduct collaborative research with a willing company for a practical application of this technology in industry. |
Novel-Concept Silicon Integrated Circuits Derived from the 3-Dimensional Device, Circuit and ArchitectureFeaturesIn recent year, facing the age of nanoscale engineering, the new technologies of device, circuit and architecture supported by novel physical guidance principles are highly expected, just as the similar situation as the predawn of semiconductor technology when Bardeen and Shockley discovered the secret of transistors. Therefore, in our research approach, the architectures, circuits, devices and CAD design tools for nanoscale LSI are systematically investigated in the following three main research subjects. Targeted Application(s)/IndustryCenter for Innovative Integrated Electronic Systems
ENDOH Tetsuo, Professor
Doctor of Engineering
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