"N" Researcher - 22 Result(s)
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Analysis and Function Elucidation of Fine Clusters and Defects in Materials Invisible by Electron MicroscopyFeaturesIt is well known that nano-scale impurity/solute clusters, defects, defect clusters and their complexes affect the mechanical and electrical properties in materials. However, it is very difficult to observe these objects even by state-of-the-art electron microscopes. We overcome the difficulty by employing noble two techniques: laser three-dimensional atom probe (3D-AP) technique and positron annihilation spectroscopy (PAS). Laser 3D-AP can map out each atom in various materials (metals, semiconductors, insulators) in three-dimensional real space with nearly atomic scale resolution. PAS can detect vacancy-type defects and defect-impurity complexes very sensitively. Targeted Application(s)/IndustryBy combining these methods, we are going to reveal the functions of the fine impurity clusters and defects to the materials: developments of new nano-structured materials, the mechanism of degradation of aged structural materials, the fall in the yield of semiconductor device production, and developments of quantum devices etc. |
Eco-Material ProcessingFeaturesThe major subject of our group is ferrous process metallurgy including thermodynamics of metals, alloys and molten slags, high temperature heterogeneous kinetics, phase equilibria of complex oxide systems and so on. We are interested in physic-chemical fundamentals of processing of metals, slags, scrap and waste. Recently our research interests are extended to multidisciplinary area so-called "Industrial Ecology" by the combination of process metallurgy, LCA (life cycle assessment) and social science such as econometrics. Targeted Application(s)/IndustryTypically our research group is aggressively working in the area of material flow analysis of critical metals considering the quality of recycled materials. Currently our major research partners are steel and non-ferrous industries, while we do hope to collaborate with waste treatment company, mineral industry and an administrative organ. Department of Metallurgy, Graduate School of Engineering
NAGASAKA Tetsuya, Professor
Doctor of Engieering
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Assessment of Physical Activities Using Wearable SensorsFeaturesMaintaining appropriate amount of physical activity is essential for health and disease prevention. Gait is the most common type of physical activity in everyday life. Monitoring the amount of physical activity in everyday lives may benefit mainly those who are at threat of metabolic syndrome and overweight. Towards better estimation of the amount of physical activity utilizing wearable sensors, we focused on taking running and walking economy into account. The relationship between step length and oxygen uptake was first determined. Step length estimation with moderate accuracy was accomplished using acceleration signals during walking. Step length was then taken into energy expenditure calculation as one of the variables. Targeted Application(s)/IndustryTogether with the basic version of the current locomotion monitoring system capable of counting staircase climbing up & down, we managed to upgrade our locomotion monitoring system into 3 dimensional. |
Development of Intelligent Molecules for the Regulation of Gene Expression in CellsFeaturesThe artificial control of gene expression by synthetic oligodeoxynucleotides (ODNs) has been the subject of considerable interest. In particular, ODNs conjugated with a cross-linking agent have been expected to enhance the inhibitory effect. Recently, microRNAs (miRNA) endogenously expressed small regulatory non-coding RNAs, are recognized as playing a critical role in regulating gene expression and the great concerns have been raised about efficient antisense oligonucleotides against miRNAs. We have already demonstrated that ODNs bearing a 2-amino-6-vinylpurine (2-AVP) derivative exhibited efficient interstrand cross-linking to cytosine selectively. The unique structural features of AVP are to possess both the hydrogen bond donor-acceptor sites as recognition sites and the vinyl group as a reactive moiety in a single molecule. Recently, we have developed of the novel cross-linking agents, which are designed based on the unique structure of AVP. These derivatives can react to thymine at the complementary site with highly selective and efficient under neutral conditions. We hope to conduct collaborative research with a willing company for a practical application of this technology in industry. Targeted Application(s)/IndustryInstitute of Multidisciplinary Research for Advanced Materials
NAGATSUGI Fumi, Professor
PHD
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Photo-Functional Advanced Materials for Nanofabrication by Nanoimprint LithographyFeaturesNakagawa group has dedicated to pursue scientific principles for molecular control of interface function occurring at polymer/other material interfaces and to put them into practice in nanoimprint lithography promising as a next generation nanofabrication tool. We are developing advanced photo-functional materials such as sticking molecular layers for "fix by light", UV-curable resins and antisticking molecular layers for "preparation by light", fluorescent resist materials for "inspection by light", and hybrid optical materials "available to light" and new research tools such as mechanical measurement systems to evaluate release property of UV-curable resins. Targeted Application(s)/IndustryOur research aims at creating new devices to control photon, electron, and magnetism. Institute of Multidisciplinary Research for Advanced Materials
NAKAGAWA Masaru, Professor
Doctor of Engineering
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Changing Corporate In-Service TrainingFeaturesWe have developed a system named PF-NOTE that the system uses video cameras, clickers and a computer to bookmark an audience's clicker feedback into simultaneously recorded video. We are also doing research for creating effective education or learning programs by using the developed system. The system has been mainly used for reflective learning, and we have found that this system is effective in various situations for both teacher and learners, such as practice teaching for early career teachers, developing presentation skills, and developing discussion skills. Targeted Application(s)/IndustryWe offer PF-NOTE system(s) and education/learning program(s) to companies that are of particular interest with respect to communication skills training, passing skills to the younger generation of employees, observation skill training and job interview training. Graduate School of Educational Informatics Research Division
NAKAJIMA Taira, Associate Professor
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Forecasting eruption transition through geologic and petrologic approachesFeatures1) In addition to geophysical observations, recent advances in volcanic stratigraphy and petrology would make us possible to forecast the transition of volcanic eruptions. We have been developing near-real-time volcanology based on the erupted materials in an early eruption stage. Targeted Application(s)/IndustryDepartment of Earth Science, Graduate school of Science
NAKAMURA Michihiko, Professor
Doctor of Science
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Experimental Nuclear PhysicsFeatures1) Study of strangeness nuclear physics and hypernuclei with high energy electron/photon beams Targeted Application(s)/IndustryDepartment of Physics, Graduate School of Science
NAKAMURA Satoshi N., Professor
Doctor of Science
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Analysis of Biological Signals and VisualizationFeaturesRecent development of sensor technology and ICT have enabled collection and acculumation of huge amount and wide variety of biological data. We have been investigating analysis and processing methods of the biological data for supporting clinical diagnosis and health care. For example, development of extraction algorithm of fetal electrocardiogram from maternal abdominal siglnals, and estimation and visualization algorithms of status of autonomic functions based on diverse biological signals. Targeted Application(s)/IndustrySystem development of biosignal anaysis, visualization, and diagnosis. Graduate School of Information Sciences
NAKAO Mitsuyuki, Professor
Doctor of Engineering
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Integrated Design for Sustainable Energy SystemsFeaturesThe concept of LCS (low carbon society) is a unique approach having multi-dimensional considerations such as social, economic and environmental dimensions. The LCS aims at an extensive restructuring of worldwide energy supply/demand network system by not only replacing the conventional parts with the new ones, but also integrating all the necessary components and designing absolutely different energy networks. An energy-economic model is a tool for decision making for a variety of purposes, such as energy security planning, climate policy analysis, and technology innovation assessment. Targeted Application(s)/IndustryProvide local governments, participating companies, and consultants with databases related to local energy supply and demand to support data analysis and scenario design in planning smart cities and decarbonized regions. Department of Management Science and Technology , Graduate School of Engineering
NAKATA Toshihiko, Professor
Doctor of Engineering
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Carbon Neutral Design TheoryFeaturesAssist in designing communities to be carbon neutral by 2050. Provide an internationally compatible regional energy supply and demand database under development to support current analysis and rational scenario design for the future. Support the design of regional energy systems based on up-to-date analysis of the renewable energy potential of each region, including hydrogen energy and LCA assessments, to meet regional and industry needs, and provide methods for performance analysis and value assessment. Targeted Application(s)/IndustryThose in charge of the implementation plan for a decarbonized society and the carbon neutral plan, which is an extension of the basic environmental plan, at local governments. Department of Management Science and Technology , Graduate School of Engineering
NAKATA Toshihiko, Professor
Doctor of Engineering
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Regulation of ABC Transporters in Colorectal CancerFeaturesColorectal cancer (CRC) is one of the most common types of cancer worldwide. Surgical resection is the only curative treatment available for primary CRC. We determined the gene expression profiles for ATP binding cassette (ABC) transporters by RNA sequencing in matched colon cancer and normal colon tissue specimens in order to provide insight into the regulatory mechanisms underlying expression of transporters related to colon carcinogenesis. The expression of ABCC3 was repressed by Wnt signaling pathway, suggesting downregulation of ABCC3 might contribute oncogenesis. Targeted Application(s)/IndustryRecently, we easily obtain comprehensive data including transcriptome and other omics data. These data are expected to help find a target for drug development, expecting that pharmaceutical industry interpret and extract new knowledge from them. |
Elucidation of oncogenesis by Fbxw7FeaturesIn life science research field, it is noteworthy issue how information in genome is interpreted and is transferred to functional molecules. However, during these 10 years, we convinced that the amount of proteins, final functional molecules was regulated by not only by production but also by degradation. For examples, the amount of c-Myc, which promotes cell cycle and inhibits cell death, increase in many types of cancer by failure of protein degradation. Targeted Application(s)/Industry |
Philosophy of Science and Technology, Science and Technology Studies (STS)FeaturesMy research area is mainly phenomenology, philosophy of technology, and applied ethics (engineering ethics etc.). Technological Artifacts mediate human activities. So designing artifacts is in itself an ethical behavior. Analysing the ontological structure of the artifacts, describing the epistemological propcess of desingning activities, evaluating the social and ethical influence of artifacts are main issues in philosophy of technology. On the basis of such philosophical investigations, we can develope ethical studies concerining how engineerss, companies can recognize ethical issues in a networks of meanings , how they can make ethical decision among engineers and users. Targeted Application(s)/IndustryI hope to conduct cooperative research on ethical education of engineers, as well as on human-machine interaction. |
Performance enhancement and application development of energy harvesting materials by microstructure designFeaturesTo realize IoT society, it is required the sensors, which function without battery charge. We study on energy harvesting materials using our knowledge about materials mechanics and numerical simulation such as finite element method. We recently address to develop energy harvesting devices, which can recovery the unharnessed energy around us as electrical energy. Targeted Application(s)/IndustryDepartment of Materials Processing, Graduate School of Engineering
NARITA Fumio, Professor
Doctor of Engineering
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Nonprofit Organizations and Social CapitalFeaturesNonprofit organizations strive to solve community and social problems and to create new social values. Nonprofit organizations have the role to create citizenship and social capital - trust, norms and networks - in community. Social capital, an invisible and soft capital has increasingly become important to a sustainable management of an organization. Graduate School of Economics and Management
NISHIDE Yuko, Professor
Doctor of International Public Policy
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Religion, language, society, and life in ancient IndiaFeaturesTargeted Application(s)/Industry |
Development of functional concreteFeaturesConcrete, which supports human society, is the research target for developing various functions. For example, research targets include fiber-reinforced cementitious composite (FRCC) to improve mechanical properties, self-healing concrete to improve durability, and a concrete 3D printing system to enable free modeling. The functional concrete materials will be a means to meet the needs for concrete materials in recent years. Targeted Application(s)/IndustryConstruction companies, maintenance management, building materials manufacturers, etc. Department of Architecture and Building Science, Graduate School of Engineering
NISHIWAKI Tomoya, Associate Professor
Dr. Eng.
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Bio-Hybrid MEMS for Medical, Environmental and Food EngineeringFeaturesWe have developed original manufacturing techniques for bio-hybrid MEMSs that utilize special functions of bio-elements, proteins and living cells, for molecular selective sensing and power generation from natural fuels. Targeted Application(s)/IndustryWe hope to conduct collaborative research with a willing company for a practical application of these technologies in industry. Department of Bioengineering and Robotics, Graduate School of Engineering
NISHIZAWA Matsuhiko, Professor
Doctor of Engineering
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The Novel Ultrasound Irradiation DeviceFeaturesDr. Katsunori Nonogaki has developed the novel ultrasound irradiation device, which can improve the autonomic nervous system activity and peripheral circulation. In addition, the ultrasoud device can improve hypertension and hyperglycemia within 20 min in subjects with drug-resistant hypertension and diabetes. Our initial device was approved in Japan (226AIBZX00028000). This device will be avaliable for the treatment of 1) muscle pain, 2) the autonomic neural dysfunction and stress-related disorders, 3) hypertention, and 4) diabetes. Moreover, the device will be usefull for your healthy life and aging care. Targeted Application(s)/IndustryOur aims are to export the device internationally. We seek the investment and international business partners. Department of Diabetes Technology, Graduate School of Biomedical Engineering
NONOGAKI Katsunori, Professor
MD, PhD
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