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Research Themes - 252 Result(s)

 C

Converting Food Waste into Valuable Materials with Hot-Compressed Water Treatment

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特徴・独自性
  • Treatment with hot-compressed or subcritical water is an attractive process for converting food waste into valuable materials. Water is an environmentally acceptable solvent and is cost effective; thus, hot-compressed water has recently received attention as a medium for resource recovery from waste. We chose fish gelatin as a model of marine food waste (especially fish skin fraction), and we determined the optimum conditions for the degradation of fish gelatin with hot-compressed water between 160 and 240 °C at 2 MPa. These conditions were optimized in terms of maximizing the concentrations of specific degradation products, such as peptides, and ACE inhibitory.
実用化イメージ

The disposal of fish waste has become a serious problem in marine food industries because approximately half of the fish mass, including the skin, bones, entrails, and some meat. The feasibility of converting organic waste by hot-compressed water (subcritical water treatment) into useful resources has been demonstrated together with Industry.

Researchers

Graduate School of Agricultural Science

Tomoyuki Fujii

Creation of a high functional bio-interface using laser fabrication

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特徴・独自性
  •  Using laser fabrication, we are developing techniques to enhance material surface properties and functionality. For example, to create a functional interface, we aim to clarify, by way of simulation and experimentation, the phenomenon that occurs when the surface of a material is irradiated using a laser beam.
  •  We expect that the results of our research will be widely applicable, including biomedical devices.
  • ■ Creation of biocompatible surfaces
  •  Materials used for artificial organs, vessels, and other bio-implants require excellent tissue and cell biocompatibility. Therefore, we are exploring the creation of biocompatible surfaces using a new laser irradiation process in this study.
  •  We have succeeded in imparting a biologically active function to titanium-based materials by applying the laser irradiation technique. When such a material that has a biologically active function is inserted in a living body, hydroxyapatite (the principal constituent of bones and teeth) precipitates on the surface. Using the laser irradiation technique, we can manufacture bone-adherent implants, and we envisage their application to artificial joints or dental implants.
  •  This research aims to discover such breakthrough solutions for biomedical applications using the laser irradiation technique.
実用化イメージ

Researchers

Green Goals Initiative

Masayoshi Mizutani

Creation of cancer cell specific oligonucleotide therapeutics

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特徴・独自性
  • Focusing our reseach interest mostly on the recognition and complexation behavior control of bioplymrs, such as DNA/RNA, proteines and so on. Another topics are reaction control based on molecular recognition phenomena in both ground and electronically excited states, we are pursuing mechanistic and synthetic studies on asymmetric photochemistry with supramolecular biopolymers as chiral reaction fields.
実用化イメージ

Researchers

Institute of Multidisciplinary Research for Advanced Materials

Takehiko Wada

Cyber Physical Systems Security and Its Applications

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特徴・独自性
  • Our study focuses on information security technologies for the next-generation ICT society fusing real-world and cyber-space computing. We are now conducting the research and development of ultra-high-speed, ultra-low power LSI computing to perform security functions such as encryption and secure computing, secure implementation technologies to protect systems from various physical attacks (attacks carried out by physical access to the system), and security optimization technologies tailored to the system usage environment and application area.
実用化イメージ

We can provide collaboration and information exchange services in the fields of information security. In particular, we have experiences of domestic/international collaborative researches on embedded security with some companies, universities, and governmental institutes.

Researchers

Research Institute of Electrical Communication

Naofumi Homma

 D

Data Analytics for Creation of Social Values

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特徴・独自性
  • My research field is a data analytics for creation of social values by data science approaches. In modern society, we can observe various data sets about our daily life, business or community. I aim to create new services for it using such data set and methods of Bayesian modeling, data mining or machine learning.
実用化イメージ

Researchers

Graduate School of Economics and Management

Tsukasa Ishigaki

Design and control of new weld interface during welding of dissimilar materials

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特徴・独自性
  • Welding of dissimilar materials is an important process to manufacture the future structures and devices, but it is hard to produce the high-performance welds because the excessive reaction at the weld interface deteriorates the weld properties. Our group attempts to develop the new dissimilar welding process to yield the new interface with the aimed properties through design and control of interfacial reaction as well as usage of solid-state welding processes, such as friction stir welding and ultrasonic welding.
実用化イメージ

We hope to have collaborative researches with willing companies for practical application of welding of dissimilar materials, including metal/metal and metal/thermoplastic composite, in transportation, infrastructure, and energy industries.

Researchers

Graduate School of Engineering

Yutaka Sato

Design and Development of 50 kg-class Micro Satellites

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特徴・独自性
  • We design and develop micro satellites in a format of 50 cm cubic size and 50 kg mass. We have developed the first and second micro satellites of Tohoku University, named “RISING” and “RISING-2”, launched by using JAXA’s H-IIA rocket vehicle in January 2009 and May 2014, respectively. Both satellites are operated from our ground station in the university. Particularly, RISING-2 has succeeded in capturing high precision color images of the Earth's surface at a spatial resolution of 5m, the highest in the world among 50kg-class satellites. Now the third micro satellite for international science mission is under the development. In addition, we are active in nano satellite development. The first nano-sat “RAIKO” in a 10 by 10 by 20 cm format was launched from the International Space Station in 2012. More nano-sats are under the development.
実用化イメージ

We would like to make innovation in space business by introducing a new paradigm for rapid and low cost development of space systems for various missions of remote sensing, earth observation, and space exploration. We have rich experience in the development of spacecraft bus systems, onboard avionics systems and mission instruments. Collaborations with technology and business partners are welcome.

Researchers

Graduate School of Engineering

Kazuya Yoshida

Design and Fabrication of Micro-Optical Devices Based on Optics, Especially Optical MEMS and Sensors

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特徴・独自性
  • On the basis of optical engineering, optical technologies for sensing mechanical motion, spectroscopic properties, and other physical/chemical characteristics are investigated. Moreover, using semiconductor micro/nano-fabrication technology, integrated micro-optical sensors, micro/nano optical systems, optical micro-electro-mechanical systems (MEMS) are studied. Micro laser scanner for display, deformable mirror for telescope, optical displacement encoder, and fluorescent analysis system are the examples of research topics.
実用化イメージ

Optical design, Optical industries, Industries relating to semiconductor micro fabrication and MEMS, optical telecommunications, etc.

Researchers

New Industry Creation Hatchery Center

Kazuhiro Hane

Design, fabrication and test of high performance miniaturized sensor and actuator systems

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特徴・独自性
  • Micro and nano electro-mechanical systems (MEMS/NEMS) have completely changed human society in the past decades. Many devices that are taken for granted these days like smart phone, future car and drone would be unthinkable without them.
  • The integration of various new kinds of materials, such as metallic glass and nanostructures into micro technologies allows us to create devices with novel performance and characteristics; examples include acoustic sensors and actuators, thermoelectric generators and wafer level packages.
  • In collaboration with partners inside and outside Tohoku University, technologies are being developed that can be transferred to industry ranging from material integration and processes to packaging and reliability.
実用化イメージ

Wide collaboration in Microsystem technology is possible. We develop, implement and optimize processes, devices and systems until they are ready for use, keeping in mind reliability, yield and other important features for commercialization. We work with also with partners, such as Fraunhofer. Flexible interlinking of expertise and capacities with other research groups enables us to meet broad project requirements and create complex system solutions.

Researchers

Micro System Integration Center

Froemel Joerg Eckhardt

Developing energy creation and saving materials

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特徴・独自性
  • Most innovations have been triggered by advent of new materials. We focus on to explore new inorganic materials and their synthesis routes on the basis of our knowledge about the material design and various materials processing technologies. We develop proton conducting phosphate glasses working at intermediate temperatures and narrow gap oxide semiconductors applicable in visible and NIR regions. Thin-film solar cells, fuel cells using those materials are also developing.
実用化イメージ

We focus on oxide semiconductors and proton conducting electrolytes and electrodes in order to apply them in solar cells, fuel cells, light-emitting devices. But, applicable area of our technologies is not limited in those applications.

Researchers

Institute of Multidisciplinary Research for Advanced Materials

Takahisa Omata

Developing plastic waste sorter using Terahertz waves and social implementation of sustainable recycling technology

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概要

This research utilizes the characteristics of terahertz waves, used in next-generation communications and autonomous driving, to identify the materials of plastic waste. It improves existing recycling technologies and can be applied to evaluate the quality of recycled plastics, ensuring stable production of high-quality recycled plastics. It enables easy development of devices to solve various issues in containers and packaging and automobile recycling, contributing to the realization of decarbonization and a circular economy.

従来技術との比較

Conventional plastic waste identification and sorting technologies use specific gravity sorting or near-infrared devices. Particularly, near-infrared sorting technology has accumulated an enormous amount of data and serves as the primary sorting technology in plastic recycling plants. However, near-infrared devices struggle with identifying black plastics, additives, and degradation. This technology uses terahertz waves to measure and evaluate transmission and absorption characteristics, allowing for identification of black plastics, additives, and degradation.

特徴・独自性
  • In recent years, there has been increasing global attention on plastic waste issues, such as marine pollution from drifting garbage and microplastics, the overseas export of plastic waste resources, and the increase in disposable containers like plastic bags and straws, especially due to the impact of COVID-19. There is growing demand for advanced identification and recycling of plastic waste materials, especially in the context of achieving the Sustainable Development Goals (SDGs) and realizing a circular economy.
  • The research group from Tohoku University, Shibaura Institute of Technology, and Shizuoka University has conducted research on the commercialization of advanced sorting devices for plastic packaging waste. We have successfully identified mixed plastics containing black plastics, additives, and flame retardants, which were difficult to identify with existing devices, by utilizing the characteristics of terahertz waves. We have also confirmed the ability of terahertz waves in assessing degradation caused by UV or long-term use. Furthermore, the method has been shown to be effective for distinguishing bioplastics, which is expected to see increasing demand in the future, in addition to plastic waste from container packaging, automobiles, and home appliances.
  • These identification technologies can be applied to properly sort plastic waste generated by the “The Plastic Resource Circulation Act,” enacted in 2022, contributing greatly to securing high-quality recycled resources through plastic waste resource recycling.
  • Our research group conducts interdisciplinary research with experts in various fields: social engineering, resource circulation (Professor Jeongsoo YU), optical engineering (Professor Tadao TANABE of Shibaura Institute of Technology and Professor Tetsuo SASAKI of Shizuoka University), information science and big data analysis (Associate Professor Kazuaki OKUBO), data collection and analysis, international cooperation (Specially Appointed Lecturer Gaku MANAGO), social experiments, and behavioral economics (Assistant Professor Xiaoyue LIU). We address the needs from social, economic, and environmental issues both domestically and internationally, working from diverse perspectives to solve challenges and contribute to the creation of a sustainable society. Collaboration and networking with private companies, government agencies, research institutions, and civic organizations are also expected.
実用化イメージ

This technology can be applied to the development of plastic waste identification and sorting devices from processes such as containers and packaging recycling, automobile recycling, and home appliance recycling, as well as the production and quality evaluation of recycled plastics.

Researchers

Graduate School of International Cultural Studies Graduate School of Environmental Studies Green Goal's Initiative, Tohoku University

Jeongsoo Yu

Development and evaluation of various inhibitors and disinfectants for SARS-CoV-2

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特徴・独自性
  • Using the infectious SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2), we are evaluating and developing new therapeutic drug candidates as well as evaluating disinfectants. Further analyses such as mechanism of action and resistance may be applicable. Other pathogens, including influenza virus and drug-resistant bacteria, will be examined upon request and discussion. Through joint and collaborative research with domestic and overseas pharmaceutical companies and related companies, we have experience of their clinical application including basic research.
実用化イメージ

We support development and evaluation of various inhibitors and disinfectants for variants of SARS-CoV-2 as well as wild type.

Researchers

International Research Institute of Disaster Science

Eiichi Kodama

Development of a Novel Quantification Method for Diarrhetic Schell Fish Poisoning

特徴・独自性
  • We have investigated isolation and structure determination of natural products and evaluated mode of their actions. We have especially focused on marine natural products causative for a food poisoning, diarrheic shellfish poisoning (DSP), which has spread worldwide and threatened regional fishery industry. Dinophysistoxin produced by the dinoflagellate Dinophysis spp. and okadaic acid, are thought to be responsible for DSP. Acute toxicity test using mice has been the primary method for detection of DSP in the fish market, though an alternative method to quantify DSP without sacrificing mice has been requested. We isolated OABP2, a novel okadaic acid binding protein, from the marine sponge Halichondria okadai and succeeded in expression of the recombinant OABP2 in E. coli, which eventually showed high affinity to the DSP toxins.
実用化イメージ

We are now working on visualization of OA by utilizing OABP2 in order to provide an easy and quick quantification method for DSP.

Researchers

Graduate School of Agricultural Science

Keiichi Konoki

Development of a novel therapeutic drug, TMS-007, for acute cerebral infarction

特徴・独自性
  • The currently approved fibrynolytic therapy is only alteplase, but the use of it has been limited to 5% of patients with acute cerebral infarction due to possible side effects including hemorrhagic infarction that may be life-threatening. TMS-007 is a novel drug that has both fibrynolytic activity and brain protective effects. The aim of this project is to perform a clinical trial of this drug and to further achieve a commercial-based clinical use. We believe that this drug would contribute significantly in the treatment of acute cerebral infarction.
実用化イメージ

Researchers

Administrative Staff

Teiji Tominaga

Development of a Numerical Prediction System for Sliding Part Wear and Seizure Occurrence Portions

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概要

Focusing on the lubricant film flow with phase change between the engine piston pin and connecting rod small end, we developed a new multiphase fluid-structure coupled analysis method that takes into account elastic deformation of the structure and flow path changes and developed a simulation prediction method for tribological properties under high load conditions. The simulation prediction method for tribological properties under high load conditions has been created. As a result, we succeeded in simulation prediction of the wear/seizure generating areas in sliding parts. We discovered that the peculiar deformation behavior of the components is the cause of wear/seizure.

従来技術との比較

It has been thought that computational prediction is impossible to verify the wear and seizure locations in fluid lubrication. Still, this study succeeded in the simulation prediction of wear and seizure locations in sliding parts.

特徴・独自性
  • Numerical prediction of the wear and seizure locations in the sliding parts of engine piston pins was successfully performed.
  • The bow-like deformation of the piston pin was identified as the cause of mechanical contact and seizure at the connecting rod edge.
  • A three-dimensional multiphase fluid-structure coupled analysis method has been successfully developed, considering the piston pin's elastic deformation and connecting rod and thin-film cavitation1 lubrication with unsteady flow path changes.
実用化イメージ

This research method applies to automotive engines and all sliding component elements using fluid lubrication. It contributes to damage prediction and the development of safety guidelines for transportation and industrial machinery components, enabling the optimal design of components.

Researchers

Institute of Fluid Science

Jun Ishimoto

Development of a reaction process in supercritical water

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特徴・独自性
  • We are developing a new continuous flow type process for supercritical reactions. Under the supercritical state, the organic molecules and metal salt aqueous solutions are miscible and water molecule works as an acid/base catalyst which leads to rapid reactions. In order to apply such new reaction fields to an industrial process, it is necessary to establish the process design basis by understanding phenomena in the reaction fields, on the basis of phase equilibrium, flux and reaction kinetics theory. So while developing a process, we are doing research for the establishment of the process design basis.
実用化イメージ

Examples are a process for the synthesis of organic modified nanoparticles (MPs), a process for the pretreatment and solubilization of biomass in the supercritical/subcritical water and a process for the refinery of heavy oil in the supercritical water.

Researchers

Advanced Institute for Materials Research

Tadafumi Ajiri

Development of Advanced Device and Process Technologies and New Image Sensors

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特徴・独自性
  • Toward the ultimate performances of image sensors, advanced research activities are being conducted that cover a wide range of technology fields from cleanroom infrastructure, materials, process equipment, process, device, circuit, assembly, signal processing, measurement/evaluation and reliability. Following technologies have been successfully commercialized:
  • A fast and accurate measurement technology of electrical characteristics for over 1 million transistors
  • A wide dynamic range CMOS image sensor technology capturing images over five decade brightness ranges
  • An ultra-fast CMOS image sensor technology with 10 million frames/sec
実用化イメージ

Followings are available for industry collaborators:
A. 200mm-diameter-wafer silicon device fabrication utilizing the ultra-clean facility including wafer mutual fabrication processing between device manufacturers.
B. Process technology development and various kinds of analyses.
C. Development of new image sensors.

Researchers

New Industry Creation Hatchery Center

Shigetoshi Sugawa

Development of an Industrial Instrument / the Medical Equipment Using the Contactless Power Transmission System

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特徴・独自性
  • Using a non-contact power transmission technique, we develop an industrial instrument and the medical equipment. In the industrial instrument, we deal with the wide non-contact electricity transmission of the dozens of kW class from mW class from a small size electric apparatus represented by a cell-phone to the factory carrier device. In addition, we develop the contactless electricity transmission to an artificial heart (TETS) and a functional electrical stimulator (FES) aiming at the exercise of limbs inconvenience person function rebuilding mainly in the medical equipment.
実用化イメージ

We develop soft-heating hyperthermia using the small implantation element which does not need an internal temperature measurement as cancer treatment.

Researchers

International Research Institute of Disaster Science

Hidetoshi Matsuki

Development of an intranodal administration method

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特徴・独自性
  • The amount of anticancer drug required to treat one metastatic lymph node is 1/1,000 to 1/10,000 of the systemic dose.
  • The drug can be administered into the lymph node under ultrasound guidance.
  • An international patent has been filed for the solvent of the administered drug.
実用化イメージ

1. Treatment and prophylactic therapy of affiliated lymph nodes in head and neck cancer, breast cancer, etc.
2. Pharmaceutical companies aiming to develop drugs by drug repositioning and generics
3. Medical device manufacturers aiming to develop a dosing system

Researchers

Graduate School of Biomedical Engineering

Tetsuya Kodama

Development of anti-fibrotic therapies with a cell line from myofibroblasts of fibrotic kidneys

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特徴・独自性
  • There are serious unmet medical needs in kidney diseases. Since fibrosis is a common terminal pathology of various kidney diseases and closely related to renal failure, anti-fibrotic therapies are plausible strategies for kidney diseases. Kidney fibrosis progresses with the emergence of myofibroblasts which produce extracellular matrix. We demonstrated that myofibroblasts originate from renal interstitial fibroblasts, which produce the erythroid growth factor erythropoietin, and that the transformation is reversible. To elucidate mechanisms of kidney fibrosis, we have established a cell line derived from myofibroblasts of mouse kidneys. It has been demonstrated that epigenetic interventions restore the cells (Replic cells) to their original fibroblastic features.
実用化イメージ

Replic cells provide useful and precise strategies to identify anti-fibrotic drugs.

Researchers

New Industry Creation Hatchery Center

Norio Suzuki