Tohoku University. Research Profiles

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"D" Theme - 78 Result(s)

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Data Analytics for Creation of Social Values

Features

My research field is a data analytics for creation of social values by data science approaches. In modern society, we can observe various data sets about our daily life, business or community. I aim to create new services for it using such data set and methods of Bayesian modeling, data mining or machine learning.

Targeted Application(s)/Industry

Graduate School of Economics and Management
ISHIGAKI, Tsukasa, Associate Professor Doctor of Philosophy

Design and control of new weld interface during welding of dissimilar materials

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Features

Welding of dissimilar materials is an important process to manufacture the future structures and devices, but it is hard to produce the high-performance welds because the excessive reaction at the weld interface deteriorates the weld properties. Our group attempts to develop the new dissimilar welding process to yield the new interface with the aimed properties through design and control of interfacial reaction as well as usage of solid-state welding processes, such as friction stir welding and ultrasonic welding.

Targeted Application(s)/Industry

We hope to have collaborative researches with willing companies for practical application of welding of dissimilar materials, including metal/metal and metal/thermoplastic composite, in transportation, infrastructure, and energy industries.

Department of Materials Processing, Graduate School of Engineering
SATO, Yutaka, Professor Ph.D.

Design and Development of 50 kg-class Micro Satellites

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Features

We design and develop micro satellites in a format of 50 cm cubic size and 50 kg mass. We have developed the first and second micro satellites of Tohoku University, named “RISING” and “RISING-2”, launched by using JAXA’s H-IIA rocket vehicle in January 2009 and May 2014, respectively. Both satellites are operated from our ground station in the university. Particularly, RISING-2 has succeeded in capturing high precision color images of the Earth's surface at a spatial resolution of 5m, the highest in the world among 50kg-class satellites. Now the third micro satellite for international science mission is under the development. In addition, we are active in nano satellite development. The first nano-sat “RAIKO” in a 10 by 10 by 20 cm format was launched from the International Space Station in 2012. More nano-sats are under the development.

Targeted Application(s)/Industry

We would like to make innovation in space business by introducing a new paradigm for rapid and low cost development of space systems for various missions of remote sensing, earth observation, and space exploration. We have rich experience in the development of spacecraft bus systems, onboard avionics systems and mission instruments. Collaborations with technology and business partners are welcome.

Department of Aerospace Engineering, Graduate School of Engineering
YOSHIDA, Kazuya, Professor Doctor of Engineering

Design and Fabrication of Micro-Optical Devices Based on Optics, Especially Optical MEMS and Sensors

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Features

On the basis of optical engineering, optical technologies for sensing mechanical motion, spectroscopic properties, and other physical/chemical characteristics are investigated. Moreover, using semiconductor micro/nano-fabrication technology, integrated micro-optical sensors, micro/nano optical systems, optical micro-electro-mechanical systems (MEMS) are studied. Micro laser scanner for display, deformable mirror for telescope, optical displacement encoder, and fluorescent analysis system are the examples of research topics.

Targeted Application(s)/Industry

Optical design, Optical industries, Industries relating to semiconductor micro fabrication and MEMS, optical telecommunications, etc.

Department of Nanomechanics, Graduate School of Engineering
HANE, Kazuhiro, Professor Doctor of Engineering

Design, fabrication and test of high performance miniaturized sensor and actuator systems

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Features

Micro and nano electro-mechanical systems (MEMS/NEMS) have completely changed human society in the past decades. Many devices that are taken for granted these days like smart phone, future car and drone would be unthinkable without them.
The integration of various new kinds of materials, such as metallic glass and nanostructures into micro technologies allows us to create devices with novel performance and characteristics; examples include acoustic sensors and actuators, thermoelectric generators and wafer level packages.
In collaboration with partners inside and outside Tohoku University, technologies are being developed that can be transferred to industry ranging from material integration and processes to packaging and reliability.

Targeted Application(s)/Industry

Wide collaboration in Microsystem technology is possible. We develop, implement and optimize processes, devices and systems until they are ready for use, keeping in mind reliability, yield and other important features for commercialization. We work with also with partners, such as Fraunhofer. Flexible interlinking of expertise and capacities with other research groups enables us to meet broad project requirements and create complex system solutions.

Advanced Institute for Materials Research
FROEMEL, Joerg, Associate Professor Doctor of Engineering

Developing energy creation and saving materials

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Most innovations have been triggered by advent of new materials. We focus on to explore new inorganic materials and their synthesis routes on the basis of our knowledge about the material design and various materials processing technologies. We develop proton conducting phosphate glasses working at intermediate temperatures and narrow gap oxide semiconductors applicable in visible and NIR regions, simple and safe synthesis routes to cadmium-free quantum dot phosphors and colloidal indium arsenide quantum dots for solar cells. Thin-film solar cells, fuel cells and light-emitting devices using those materials are also developing.

Targeted Application(s)/Industry

We focus on oxide semiconductors, proton conducting electrolytes and electrodes, quantum dots and nanocrystals in order to apply them in solar cells, fuel cells, light-emitting devices and displays. But, applicable area of our technologies is not limited in those applications.

Institute of Multidisciplinary Research for Advanced Materials (IMRAM)
OMATA, Takahisa, Professor Doctor of Engineering

Development and Application of Hard Porous Carbon Materials RB Ceramics Made from Rice Bran

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Features

We developed a hard porous carbon material, a RB ceramics, made from defatted rice bran. This is an effective use of the defatted rice bran after rice oil was extracted. The RB ceramics has low friction and high wear resistance without using any lubricants. We also succeeded in the development of resin composites filled with the RB ceramics particles, which exhibit low friction. On the other hand, we developed elastomeric composites filled with the RB ceramics particles as high friction materials.

Targeted Application(s)/Industry

We have conducted researches on development and applications of low-friction or high-friction materials in collaboration with many companies including small- and medium-sized enterprises, such as in industrial, sports engineering, health-care, welfare, and living-ware fields. We have successfully achieved more than 60 practical applications with the collaboration.

Graduate School of Engineering
HOKKIRIGAWA, Kazuo, Professor Doctor of Engineering

Development in Semiconductor Materials and Research of their Properties Considering Device Applications Bringing System Evolutions

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1. Development of Distributed Feedback (DFB) Laser Diodes (LD) widely used in optical communications systems realizing a highly information-based society.
2. Nitride semiconductors famous for blue light emitting diodes
(a) Proposal of InGaAlN system considering device applications in 1989
(b) Success in growth of single crystalline InGaN by metalorganic vapor phase epitaxy (MOVPE) in 1989
(c) Prediction of band-gap energy (Eg) of InN much smaller than the reported values in 1989 and its experimental confirmation in 2002
(d) Observation of photoluminescense from InGaN in 1991
(e) Prediction of phase separation in InGaAlN in 1997
We promoted the JST-CREST project "Research on InN Semiconductor Laser Diodes with High Temperature-Stability for Optical Communications Systems".

Targeted Application(s)/Industry

DFB-LD: Fabrication of periodic structure with submicron scale, Epitaxial growth of semiconductor films on the substrate with fine structures, LD fabrication process, device evaluation, and device simulation
Nitride Semiconductors: MOVPE growth, N-polar growth, evaluation of materials, fabrication of light-emitting devices, solar cells, high-power transistors, and high-power transistors

New Industry Creation Hatchery Center
MATSUOKA, Takashi, Professor Doctor of Engineering

Development of a Novel Quantification Method for Diarrhetic Schell Fish Poisoning

Features

We have investigated isolation and structure determination of natural products and evaluated mode of their actions. We have especially focused on marine natural products causative for a food poisoning, diarrheic shellfish poisoning (DSP), which has spread worldwide and threatened regional fishery industry. Dinophysistoxin produced by the dinoflagellate Dinophysis spp. and okadaic acid, are thought to be responsible for DSP. Acute toxicity test using mice has been the primary method for detection of DSP in the fish market, though an alternative method to quantify DSP without sacrificing mice has been requested. We isolated OABP2, a novel okadaic acid binding protein, from the marine sponge Halichondria okadai and succeeded in expression of the recombinant OABP2 in E. coli, which eventually showed high affinity to the DSP toxins.

Targeted Application(s)/Industry

We are now working on visualization of OA by utilizing OABP2 in order to provide an easy and quick quantification method for DSP.

Graduate School of Agricultural Science
KONOKI, Keiichi, Associate Professor PhD

Development of a novel therapeutic drug, TMS-007, for acute cerebral infarction

Features

The currently approved fibrynolytic therapy is only alteplase, but the use of it has been limited to 5% of patients with acute cerebral infarction due to possible side effects including hemorrhagic infarction that may be life-threatening. TMS-007 is a novel drug that has both fibrynolytic activity and brain protective effects. The aim of this project is to perform a clinical trial of this drug and to further achieve a commercial-based clinical use. We believe that this drug would contribute significantly in the treatment of acute cerebral infarction.

Department of Neurosurgery, Graduate School of Medicine
TOMINAGA, Teiji, Professor Doctor of Medicine

Development of a Novel Therapy for Amyotrophic Lateral Sclerosis (ALS) Using Hepatocyte Growth Factor (HGF)

Features

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by systematic motor neuron degeneration. Approximately 20% cases of familial ALS are caused by mutations in the superoxide dismutase 1 (SOD1) gene. We developed transgenic rats that express a human SOD1 gene with two different ALS-linked mutations (G93A or H46R) showing progressive motor neuron degeneration and paralysis. The larger size of the rat ALS models as compared with existing mouse models will facilitate studies on neuroprotective and neuro-regenerative strategy involving manipulations of cerebrospinal fluid and spinal cord.

Targeted Application(s)/Industry

Hepatocyte growth factor (HGF) is one of the most potent survival-promoting factors for motor neurons. Continuous intrathecal infusion of human recombinant HGF (hrHGF) attenuated loss of spinal motor neurons, astrocytosis, and microglial activation, leading to prolonged survival in the ALS rats. Safety and toxicology testing of the hrHGF protein in non-human primates should prompt further clinical trials in human ALS patients.

Department of Neurology, Graduate School of Medicine
AOKI, Masashi, Professor Doctor of Medicine

Development of a reaction process in supercritical water

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We are developing a new continuous flow type process for supercritical reactions. Under the supercritical state, the organic molecules and metal salt aqueous solutions are miscible and water molecule works as an acid/base catalyst which leads to rapid reactions. In order to apply such new reaction fields to an industrial process, it is necessary to establish the process design basis by understanding phenomena in the reaction fields, on the basis of phase equilibrium, flux and reaction kinetics theory. So while developing a process, we are doing research for the establishment of the process design basis.

Targeted Application(s)/Industry

Examples are a process for the synthesis of organic modified nanoparticles (MPs), a process for the pretreatment and solubilization of biomass in the supercritical/subcritical water and a process for the refinery of heavy oil in the supercritical water.

Advanced Institute for Materials Research
ADSCHIRI, Tadafumi, Professor Doctor of Engineering

Development of Advanced Device and Process Technologies and New Image Sensors

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Features

Toward the ultimate performances of image sensors, advanced research activities are being conducted that cover a wide range of technology fields from cleanroom infrastructure, materials, process equipment, process, device, circuit, assembly, signal processing, measurement/evaluation and reliability. Following technologies have been successfully commercialized:
A fast and accurate measurement technology of electrical characteristics for over 1 million transistors
A wide dynamic range CMOS image sensor technology capturing images over five decade brightness ranges
An ultra-fast CMOS image sensor technology with 10 million frames/sec

Targeted Application(s)/Industry

Followings are available for industry collaborators:
A. 200mm-diameter-wafer silicon device fabrication utilizing the ultra-clean facility including wafer mutual fabrication processing between device manufacturers.
B. Process technology development and various kinds of analyses.
C. Development of new image sensors.

Management Science and Technology, Graduate School of Engineering
SUGAWA, Shigetoshi, Professor PhD

Development of an Industrial Instrument / the Medical Equipment Using the Contactless Power Transmission System

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Using a non-contact power transmission technique, we develop an industrial instrument and the medical equipment. In the industrial instrument, we deal with the wide non-contact electricity transmission of the dozens of kW class from mW class from a small size electric apparatus represented by a cell-phone to the factory carrier device. In addition, we develop the contactless electricity transmission to an artificial heart (TETS) and a functional electrical stimulator (FES) aiming at the exercise of limbs inconvenience person function rebuilding mainly in the medical equipment.

Targeted Application(s)/Industry

We develop soft-heating hyperthermia using the small implantation element which does not need an internal temperature measurement as cancer treatment.

Graduate School of Biomedical Engineering
MATSUKI, Hidetoshi, Professor Doctor of Engineering

Development of Atom-scale Spectroscopy Measurement for Nano Materials

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Scanning tunneling microscope (STM) and atomic force microscope (AFM) are among a few microscopes which enable a direct observation of atomic scale structures of materials. If compared with other electron microscope like transmission electron microscope (TEM), the energy of the electron used for STM is very low that has a big advantage of low damage for sample. Thus STM and AFM are regarded as the most important tools to characterize materials in nanotechnology. The research is now developing from a mere observation of the shape of material to the characterization specific properties of materials with an atomic scale resolution. These properties include spin and molecule vibration; well established techniques like ESR/NMR and infrared-spectroscopy requires more than billions of molecules to obtain data, while STM can obtain these data for a single molecule.
We are interested following issues and like to have a collaboration with industrial companies.
1. Molecule-scale morphological characterization of soft-material, polymers and bio material.
2. Site specific vibration spectroscopy of molecules with an atomic resolution.
3. Single spin detection with ESR-STM method
4. Developing atom-scale characterization tool

Institute of Multidisciplinary Research for Advanced Materials (IMRAM)
KOMEDA, Tadahiro, Professor Doctor of Science

Development of Biomedical Micro/Nano Integrated System Using LSI Technology

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Features

Semiconductor neural engineering is a discipline that uses semiconductor process/device/circuit technologies to further understand properties of neural systems and to create novel fusion systems of living body and machine.

Targeted Application(s)/Industry

One of the goals in this laboratory is to establish semiconductor neural engineering and develop biomedical micro/nano integrated systems.
Another goal is to educate the next generation of leaders in biomedical engineering through research including:
1. Intelligent Si neural probe and biomedical signal processing LSI
2. Fully-implantable retinal prosthesis system
3. Bio/nano technology and novel Bio-FET sensor
4. 3-dimensional integration technology and analog/digital LSI design

Graduate School of Biomedical Engineering
TANAKA, Tetsu, Professor Ph.D. (Engineering)

Development of catalytic reaction system for direct synthesis from CO2 and diols

Features

We found an effective catalyst system composed of CeO2 and 2-cyanopyridine for direct and catalytic polycarbonate formation reaction from CO2 and diols. CeO2 acted as an activator for CO2 and diols, and 2-cyanopyridine shifted the equilibrium in favor of the product side by hydration of 2-cyanopyridine, promoting the reaction. Green polycarbonates can be synthesized by combination of the catalyst system with a technique of diol syntheses from biomass.

Targeted Application(s)/Industry

This catalyst system is effective for direct transformation of CO2, contributing to the effective utilization and emission reduction of CO2. Combination of the catalyst system with a concentration technique of CO2 will bring about much advantage.

Graduate School of Engineering / Research Center for Rare Metal and Green Innovation
TOMISHIGE Keiichi, Professor Doctor of Science

Development of Compound Semiconductor Radiation Detectors

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The main research subject of our group is developing material purification methods, crystal growth methods and detector fabrication technologies for compound semiconductor radiation detectors. Our group intensely studies a compound semiconductor, thallium bromide (TlBr), for fabrication of gamma-ray detectors for the advanced radiation applications. The attractive physical properties of TlBr lie in its high atomic number (Tl: 81, Br: 35), high density (7.56 g/cm3) and wide bandgap (2.68 eV). Due to the high atomic number and high density, TlBr exhibits high photon stopping power. The wide bandgap of TlBr permits the device low-noise operation at and above room temperatures.

Targeted Application(s)/Industry

Our group focuses on development of compound semiconductor radiation detectors for advanced radiation applications including ultra-high resolution PET systems, ultra-high resolution SPECT systems, photon counting CT systems and Compton cameras. We hope to conduct collaborative research with a willing company for a practical application of this technology in industry.

Department of Quantum Science and Energy Engineering, Graduate School of Engineering
HITOMI, Keitaro, Associate Professor Doctor of Engineering

Development of devices regulating inter-organ neural network for diabetes therapy

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Diabetes induces several complications, including retinopathy and nephropathy. In patients with type 1 diabetes as well as those with type 2 diabetes, pancreatic beta cells have reportedly decreased. Therefore, regeneration therapy of pancreatic beta cells may be very effective for major populations of diabetic patients. We discovered a neuronal network, from the liver, which selectively elicits pancreatic beta cell proliferation (Science 2008, Fig.). In a murine model with insulin-deficient diabetes, stimulation of this network improved diabetes. Thus, building devices which regulate the inter-organ neuronal network may lead to “regenerative therapy” for diabetes which regenerates pancreatic beta cells in the pancreas using patients’ own cells and patients’ own systems. We hope to conduct collaborative research with a willing company for a practical application of this technology.

Center for Metabolic Diseases, Graduate School of Medicine
KATAGIRI, Hideki, Professor MD, PhD

Development of disease-resistance animals by animal breeding method and dietary additive

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The most important disease in domestic and foreign pig industry is the pig respiratory disease complex (PRDC) that the pigs show the respiratory trouble by the infection of two or more pathogens. Pigs were selected for low direction of mycoplasma pneumonia (MPS) lesion for fifth generation in a joint research with Miyagi Prefecture Livestock Experiment Station. As a result, the lesion of MPS was decreased, a natural immunity (phagocyte activity; PA, the ratio of granular leukocyte to lymphocyte; GLR) and cellular immunity increased and SRBC specific antibody production (AP) was controlled. Dietary addition of seaweed and licorice enhanced the immune function in the peripheral blood and mucosa in swine. Furthermore, dietary addition of licorice induced the enhancement of mucosal immunity and anti-inflammation effect in the peripheral tissues. These naturally derived products are useful for the reduction of dietary addition of antibiotics in the pig industry. In addition, we selected for the natural immunity, the acquired immunity, and both of the mice during 20th generation, and the immunogenic property and disease resistance of these mice were investigating. We hope to conduct collaborative research with a willing company for a practical application of this technology in industry.

Graduate School of Agricultural Science
SUZUKI, Keiichi, Professor Doctor of Agriculture