"L" Keywords - 30 Result(s)

 L

[long fatigue life]

Novel CoCr-based superelastic metallic biomaterial with low Young's modulus

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特徴・独自性
  • General metallic biomaterials, such as stainless steels and conventional CoCr alloys, show a high Young's modulus ten times higher than that of human bones. This is an unfavored feature because it causes the so-called "stress shielding effect" when they are used as implants. β-type Ti alloys have a relatively lower Young's modulus, but they come with a compromise of low wear resistance. The current novel CoCr-based alloys are a breakthrough; they exhibit both a low Young's modulus similar to human bones and a high wear and corrosion resistance. Moreover, they exhibit superelasticity with a huge recoverable strain over 17%, also showing promise as shape memory alloys.
実用化イメージ

It is the first time that a low Young's modulus, a high corrosion and wear resistance, and a superior superelastic behavior are simultaneously obtained in a single material. The current novel CoCr-based alloys are promising for biomedical applications such as total hip or knee joint replacements, bone plates, spinal fixation devices, and vascular stents.

Researchers

Graduate School of Engineering

Xiao Xu

[low power]

Development of the high-quality and low-power display system for ultra-realistic communications

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特徴・独自性
  • Recently, with a spread of high definition video streaming services and ubiquitous network, development of high-quality, ultra-realistic and low-power display systems has been demanded. We have been studying physical properties of liquid crystal materials, precise control technique of polarization, high performance liquid crystal display (LCD) devices and its application to the advanced display systems for the realization of new media such as electric paper display and digital signage display, and low-energy society. We established a polarization control technology which realizes a precise control of polarization with liquid crystal materials. By using this world-leading technology, we have been studying the control of the surface alignment of liquid crystal molecules and developed a wide-viewing angle and fast switching liquid crystal display, ultra-high definition field-sequential-color display (Fig. 1), ultra-low power reflective full-color display (Fig. 2) and large-size high-quality display system.
  • We are also studying the ultra-realistic display systems such as a spatial 3D display and a multiple directional viewing display based on the precise light control technique as a next generation interactive communication technologies (Fig.3). We hope to conduct collaborative research with a willing company for a practical application of this technology in industry.
実用化イメージ

Researchers

Graduate School of Engineering

Takahiro Ishinabe

[low temperature reforming reaction]

Low temperature reforming of hydrocarbons using metal oxide nanoparticles synthesized by supercritical method

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特徴・独自性
  • Our research group has succeeded in synthesizing various metal oxide nanoparticles with controlled size and exposure crystal planes by using organic modifiers under supercritical water conditions. The oxygen storage/release capacity of those materials in the low-temperature region is very high, and the reforming reaction of oxidative hydrocarbon proceeds at a significant rate. Besides, by combining the supercritical CO2 drying method, we have succeeded in forming a complex in which oxide nanoparticles are dispersed at a high concentration on the surface of the porous material, realizing both high oxygen storage/release capability and stability.
実用化イメージ

Low-temperature reforming reaction of biomass wastes, heavy oils, and methane. In the future, it is expected to be a technology that will lead to the construction of a low-carbon society, including CO2-free complete recycling of waste plastics.

Researchers

Advanced Institute for Materials Research

Tadafumi Ajiri

[low Young's modulus]

Novel CoCr-based superelastic metallic biomaterial with low Young's modulus

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PREV
特徴・独自性
  • General metallic biomaterials, such as stainless steels and conventional CoCr alloys, show a high Young's modulus ten times higher than that of human bones. This is an unfavored feature because it causes the so-called "stress shielding effect" when they are used as implants. β-type Ti alloys have a relatively lower Young's modulus, but they come with a compromise of low wear resistance. The current novel CoCr-based alloys are a breakthrough; they exhibit both a low Young's modulus similar to human bones and a high wear and corrosion resistance. Moreover, they exhibit superelasticity with a huge recoverable strain over 17%, also showing promise as shape memory alloys.
実用化イメージ

It is the first time that a low Young's modulus, a high corrosion and wear resistance, and a superior superelastic behavior are simultaneously obtained in a single material. The current novel CoCr-based alloys are promising for biomedical applications such as total hip or knee joint replacements, bone plates, spinal fixation devices, and vascular stents.

Researchers

Graduate School of Engineering

Xiao Xu

[low-temperature injury]

Methods to Restore Strelity of Gramineous Plants under High- and Low-Temperature Stress Conditions

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特徴・独自性
  • Plant reproductive development is more sensitive than vegetative growth to many environmental stresses. High-temperature injury is becoming an increasingly serious problem due to recent global warming. In wheat, barley, and other crops, the early phase of anther development is most susceptible to high temperature. Oppositely, grain yields in rice plants are often reduced by exposure to low temperature. Unexpected climate change, such as abnormally hot or cool summer temperatures, have occurred repeatedly during recent years. This method indicates that an appropriate use of specific phytohormones, such as auxin and GA, may promote stress tolerance and adaptation to abiotic stresses.
実用化イメージ

These potentially novel functions of the classical phytohormones will be important sustainable agriculture in the face of global climate change.

Researchers

Graduate School of Life Sciences

Atsushi Higashitani

[low-temperature plasma]

Development of Nano-Medical-Agricultural Applied Technology Using Ion-Controlled Plasma

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特徴・独自性
  • Since we have developed the techniques (ion control plasma) to generate and control ions, electrons, reactive species (radicals) in the low temperature non-equilibrium plasmas which I can touch by hand, the composite materials using nanoparticles, nanocarbons, biological molecules are synthesized in the nano-electronics field, the minimally-invasive and highly-efficient drug/gene transfection systems are developed in the medical field, and bacteria and insects are killed by the plasma in place of pesticide in the agricultural field.
実用化イメージ

The ion-controlled plasmas are applied for the minimally-invasive gene transfection system, next-generation agricultural system, the electrode material of highly-efficient battery, and so on. We hope to conduct the collaborative research with a willing company for a practical application of the novel plasma nano-medical-agricultural applied technology in industry.

Researchers

Graduate School of Engineering

Toshiro Kaneko

[Lubrication]

Development of High Performance Carbon Nanotube-Alumina Composite

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特徴・独自性
  • One of the important challenges in the development of carbon nanotubes (CNTs) reinforced ceramic composites is uniform dispersion of CNTs in the matrix. The mechanical properties of CNT/ceramics composites have been limited to date due to the formation of CNT agglomerates in the composite. We have successfully produced CNT/alumina composites with world top class strength and toughness, by employing a newly developed CNTs dispersion technique based on a flocculation method. The processing method developed in this study enables us to prepare high performance CNT materials using a pressureless sintering method.
実用化イメージ

The possible applications of the CNT/alumina composites developed in this study include tribological materials (ball bearing), biomaterials (artificial hip joint), micro-actuator materials utilizing electrostrictive effects, electromagnetic wave absorber, particularly in the frequency range of several GHz and several ten GHz.

Researchers

New Industry Creation Hatchery Center

Toshiyuki Hashida

[Lunar and Planetary Rover]

Research and Development of Space Exploration Robots

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特徴・独自性
  • We study and develop mobile robotics technology for lunar and planetary exploration. Our technology is featured by rich experience in locomotion mechanisms for highly rough terrain and advanced slippage control in loose soil environment. Also by 3D map building technology using a laser scanner for autonomous collision avoidance and for operator assistance in remote control/tele-operation. We also contributed to the design and development of Hayabusa and Hayabusa-2, which are sample-return probes developed and operated by Japanese space agency JAXA.
実用化イメージ

These technologies are also applied to terrestrial robots for such as surveillance or disaster response.

Researchers

Graduate School of Engineering

Kazuya Yoshida

[Lymph node]

Development of an intranodal administration method

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概要

The response rate of systemic chemotherapy for metastatic lymph nodes is low. This invention presents the optimal values for solvent properties, especially viscosity, in a method for directly administering drugs to lymph nodes (lymphatic drug delivery system). In 2024, a specified clinical study (jRCTs021230040) on lymph node metastasis was started at the Iwate Medical University Hospital Head and Neck Cancer Center.

従来技術との比較

In systemic chemotherapy for metastatic lymph nodes, the amount of drug delivered to the metastatic lymph nodes is small. This is due to the increase in internal pressure caused by tumor growth in the lymph nodes and the disappearance of microvessels caused by the formation of tumor mass. In this invention, we clarified the optimal viscosity range of the solvent for the lymphatic drug delivery system, which directly administers drugs to lymph nodes.

特徴・独自性
  • The amount of anticancer drug required to treat one metastatic lymph node is 1/100 to 1/1000 of the systemic dose.
  • The drug can be administered into the lymph node under ultrasound guidance.
  • An international patent has been filed for the solvent of the administered drug.
実用化イメージ

1. Treatment and prophylactic therapy of affiliated lymph nodes in head and neck cancer, breast cancer, etc.
2. Pharmaceutical companies aiming to develop drugs by drug repositioning and generics
3. Medical device manufacturers aiming to develop a dosing system

Researchers

Graduate School of Biomedical Engineering

Tetsuya Kodama

[Lymph Node metastasis]

Development of an intranodal administration method

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PREV
概要

The response rate of systemic chemotherapy for metastatic lymph nodes is low. This invention presents the optimal values for solvent properties, especially viscosity, in a method for directly administering drugs to lymph nodes (lymphatic drug delivery system). In 2024, a specified clinical study (jRCTs021230040) on lymph node metastasis was started at the Iwate Medical University Hospital Head and Neck Cancer Center.

従来技術との比較

In systemic chemotherapy for metastatic lymph nodes, the amount of drug delivered to the metastatic lymph nodes is small. This is due to the increase in internal pressure caused by tumor growth in the lymph nodes and the disappearance of microvessels caused by the formation of tumor mass. In this invention, we clarified the optimal viscosity range of the solvent for the lymphatic drug delivery system, which directly administers drugs to lymph nodes.

特徴・独自性
  • The amount of anticancer drug required to treat one metastatic lymph node is 1/100 to 1/1000 of the systemic dose.
  • The drug can be administered into the lymph node under ultrasound guidance.
  • An international patent has been filed for the solvent of the administered drug.
実用化イメージ

1. Treatment and prophylactic therapy of affiliated lymph nodes in head and neck cancer, breast cancer, etc.
2. Pharmaceutical companies aiming to develop drugs by drug repositioning and generics
3. Medical device manufacturers aiming to develop a dosing system

Researchers

Graduate School of Biomedical Engineering

Tetsuya Kodama

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