Tohoku University. Research Profiles

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"V" Keywords - 17 Result(s)

V

 V

[Valuable Elements]

Next-generation Technology Development of High-efficient Utilization of Valuable Elements

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Features

Practical materials and devices are changed by the times. Their performances of the materials are generally improved by utilizing valuable elements. In the next generation, it is required that novel materials and devices are developed, whereas it appears that the quality of minerals and raw materials is degraded. We are taking several initiatives of research and development of high-efficient utilization of valuable elements.

Targeted Application(s)/Industry

We are promoting sound industry-academia collaboration by providing reliable research results and a number of true knowledge to many people based on the research achievements we have built up to now, and also by notifying related information.

Micro System Integration Center
Shigeru Suzuki, Professor Dr. Eng.

[Vasculitis]

Development of Recombinant Inbred Mice with a Genetic Predisposition to Collagen Disease

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Eleven strains of recombinant inbred (RI) mice derived from MRL/lpr and C3H/lpr mice were established. This RI is the only one in the world that randomly develops lesions such as nephritis, arthritis, sialadenitis, vasculitis, and production of autoantibodies in each strain. The genomes of the two strains of mice are randomly held in homozygous condition, and the phenotypes of each strain and the effects of administered drugs could be compared based on their genotype maps. It is possible to identify the regions of gene loci involved in the phenotype and drug sensitivity.

Targeted Application(s)/Industry

Development of diagnostic and therapeutic agents for autoimmune diseases. It can be applied to the elucidation of the mechanism of onset of immunological adverse events caused by immune checkpoint inhibitors and the development of drugs to prevent the onset of such events, and industry-academia collaboration with pharmaceutical companies, test reagent companies, etc. is possible.

Graduate School of Biomedical Engineering
KODAMA Tetsuya, Professor PhD (Engineering), PhD (Medicine)

Development of McH-lpr/lpr-RA1 mouse, a study model that spontaneously develops severe autoimmune arthritis, vasculitis, and sialadenitis

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McH/lpr-RA1 mice are recombinant congenic mice descended from MRL/lpr and C3H/lpr mice and develop arthritis, vasculitis, and sialadenitis with high frequency and severity, with severe pannus formation similar to rheumatoid arthritis, polyarteritis nodosa, and Sjogren's syndrome. On the other hand, McH/lpr-RA1 mice do not develop systemic lymphadenopathy and severe nephritis as seen in MRL/lpr mice, so they are easy to breed and maintain and can be used for long-term drug administration experiments.

Targeted Application(s)/Industry

Development of diagnostic and therapeutic agents for collagen diseases. It can be applied to the elucidation of the mechanism of onset of immunological adverse events caused by immune checkpoint inhibitors and the development of drugs to prevent the onset of such events, etc. Industry-academia collaboration with pharmaceutical companies, test reagent companies, etc. is possible.

Graduate School of Biomedical Engineering
KODAMA Tetsuya, Professor PhD (Engineering), PhD (Medicine)

[vasohibin]

Regulation of Angiogenesis

Features

Angiogenesis, i.e., the formation of new capillaries, takes place under pathophysiological conditions including cancers, ocular neovascular diseases and atherosclerosis. Anti-angiogenic drugs have been developed, and are now in clinical use. However, because of side effects due to the damage to vascular endothelial cells, the development of anti-angiogenic drugs with different modalities is anticipated. We have isolated vasohibin-1 (VASH1) as a novel angiogenesis inhibitor expressed by endothelial cells (ECs), and vasohibin-2 (VASH2) as its homologue having pro-angiogenic activity.

Targeted Application(s)/Industry

We are planning to develop strategies of VASH1 potentiation and VASH2 inhibition. For VASH1 potentiation, we are planning to use recombinant VASH1 protein or search low molecular weight substances having VASH1 like activity. For VASH2 inhibition, we are succeeded in the development of neutralizing anti-human VASH2 monoclonal antibody.

Institute of Development, Aging and Cancer
SATO Yasufumi, Professor M.D.,PhD

[vector beam]

Development of Vector Beam and its Application to Nanoimaging

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Vector beams are very attractive because of their unique features such as small spot formation and strong longitudinal electric field near focus. We are developing a variety of generation methods of vector beams including Laguerre-Gaussian and Bessel-Gaussian beams and their higher order transverse modes. For instance, a smaller spot by approximately 30 % than that by a linearly polarized beam has been demonstrated and applied for nanoimaging.

Targeted Application(s)/Industry

Confocal scanning microscpy will benefit from vector beams as enhancement of spatial resolution. Otherwise, precision nano-processing will be possible. We are prepared to provide academic consultations to companies interested in our research.

Institute of Multidisciplinary Research for Advanced Materials
SATO Shunichi, Professor Doctor of Engineering

[Veda]

Religion, language, society, and life in ancient India

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Targeted Application(s)/Industry

Faculty of Arts and Letters
NISHIMURA Naoko, Associate Professor Doctor of Philosophy

[Video pulse]

Project “The Mirror Magical”: Remote and Non-Contact Extraction of Biological Information

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We engage in development of a cyber-medical system, “The Mirror Magical” for taking a medical check-up anytime and anywhere by use of information and communication technology (ICT). We only have to stand still in front of the mirror to check our autonomic nervous function related to baroreflex on the basis of video signals capable of remote and non-contact measurement. Demonstration experiments have been held to verify the validity of the system in estimation of blood pressure variability and the effects of physical exercise.

Targeted Application(s)/Industry

We can conduct effective collaborative research using the system not only in medical and welfare fields but also for application to smartphones, automobiles, emotion recognition robots, security cameras, sports broadcast and so on.

Center for Promotion of Innovation Strategy
YOSHIZAWA Makoto, Dr Eng

[Video stream]

Internet video streams have identities like fingerprints

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According to recent studies, each video that is streamed online has its own unique characteristic. The pattern of data that are sent through the network can vary from one encoding method to another and the change from scene to scene, which is a unique characteristic of each video. This research aims to identify video content in the network without looking at the data itself.

Targeted Application(s)/Industry

This research would be especially useful in preventing illegal distribution of television program such as illegal channel without violating user privacy. Another application would be to prevent confidential online meeting from leaking outside local enterprise network. In addition, it is also possible to investigate the circulation of a video content using method introduced by this work.

Graduate School of Information Sciences
KATO Nei, Professor Doctor of Engineering

[Virtual Reality]

Interactive Content to Enrich Our Lives

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Features

(1) Displays and Interactive Techniques
Designing original display systems to show visual information accurately and effectively, and interaction techniques to make better use of these display systems.

(2) Interactive Video Content
Creating new interactive content from real video taken by cameras and computer-generated animations.

(3) Modeling and Controlling the “Atmosphere” in a Conversation Space
Aiming to stimulate the “atmosphere” in a conversation space by supplying real-time feedback to the users, we are exploring means of sensing and analyzing change in the space.

(4) Designing and Evaluating Novel Interaction Techniques
Designing and evaluating novel interaction techniques on target selection for variety types of displays including large and touch displays.

Targeted Application(s)/Industry

Research Institute of Electrical Communication
KITAMURA Yoshifumi, Professor Doctor of Engineering

[Virus]

Development of next-generation sterilization method by a plasma flow at atmospheric pressure

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Plasma sterilization has been developed as an alternative sterilization method due to its chemical activity, operation at low temperature and atmospheric pressure, low power consumption, low cost and safety. We have studied a mechanism of chemical species generation and transport in a plasma flow and, the sterilization efficacy and mechanism for several plasma sources at atmospheric pressure, such as a microwave plasma flow, a dielectric barrier discharge in a tube and a water vapor plasma flow. We already clarified that the damages of outer membrane and destructions of the cytoplasmic membrane of Escherichia coli by exposure to the microwave plasma flow. Fig. 1 shows the effect of plasma exposure on the E. coli. When the E. coli was exposed to the plasma, the height of the E. coli decreased and the potassium leakage of cytoplasmic material increased. For sterilization in a tube, we also clarified that an induced flow in the narrow tube by DBD transports chemical species and sterilize the whole inside surface of a tube as shown in Fig. 2. We hope to conduct collaborative research with a willing company for a practical application of this technology in industry.

Institute of Fluid Science
SATO Takehiko, Professor Doctor of Engineering

[visible light]

Lethal effects of blue light on insects

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We revealed the strong lethal effect of short-wavelength visible light (blue light: 400–500 nm) on insects. That is, we found that blue light irradiation by using a common light-emitting diode (LED) can kill the eggs, larvae, pupae, and adults of various orders of insects. Our findings will provide clean and safe pest-control technique as well as important information on the hazards of exposure to visible light.

Targeted Application(s)/Industry

Graduate School of Agricultural Science
HORI Masatoshi, Professor Doctor of Philosophy

[Visual Information Processing]

Hardware Development of Brain Computer and its Application to Visual Information Processing

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Toward realizing a high-performance neuromorphic vision processing system, our research involves a neural network model of spatial perception based on motion-stereo vision and its implementation on a very large scale integrated circuit (VLSI). Important parameters for spatial perception such as time-to-contact, orientation, and the shortest distance to plane surfaces of a target object are recognized by using the model without knowing moving direction and velocity of the object. We have developed a VLSI capable of performing visual perception based on the model with low power consumption, reduced less than 1/100 compared with a commercial CPU.

Targeted Application(s)/Industry

Targeted applications include a drone flying autonomously equipped with collision avoidance system by visual perception. Targeted industry includes infrastructure inspection, agriculture, logistics, and so on.

Research Institute of Electrical Communication
SATO Shigeo, Professor Ph.D (Information Science)

[Visual recognition]

Advanced Vision System with Less Calibration

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The difficulties of introducing robot systems in production line are maintenance of environment and teaching of robot motion. Environ recognition and motion teaching using vision system will greatly improve the difficulties. However, calibration of vision-robot system is tedious and troublesome. Feedback control using vision sensor information will allow robustness against environment and teach by showing. This technique is called visual servo.

Targeted Application(s)/Industry

Visual servo will allow flexible camera setting, calibration-less system setting, and easy teaching.

Graduate School of Information Sciences
HASHIMOTO Koichi, Professor Doctor of Engineering

[Visual servo]

Advanced Vision System with Less Calibration

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Features

The difficulties of introducing robot systems in production line are maintenance of environment and teaching of robot motion. Environ recognition and motion teaching using vision system will greatly improve the difficulties. However, calibration of vision-robot system is tedious and troublesome. Feedback control using vision sensor information will allow robustness against environment and teach by showing. This technique is called visual servo.

Targeted Application(s)/Industry

Visual servo will allow flexible camera setting, calibration-less system setting, and easy teaching.

Graduate School of Information Sciences
HASHIMOTO Koichi, Professor Doctor of Engineering

[volcanic ash]

Forecasting eruption transition through geologic and petrologic approaches

Features

1) In addition to geophysical observations, recent advances in volcanic stratigraphy and petrology would make us possible to forecast the transition of volcanic eruptions. We have been developing near-real-time volcanology based on the erupted materials in an early eruption stage.
2) Automation of textural analyses of erupted materials, Risk assessment of volcanic eruption based on eruption stratigraphy

Targeted Application(s)/Industry

Department of Earth Science, Graduate school of Science
NAKAMURA Michihiko, Professor Doctor of Science

[volcanic eruption]

Forecasting eruption transition through geologic and petrologic approaches

Features

1) In addition to geophysical observations, recent advances in volcanic stratigraphy and petrology would make us possible to forecast the transition of volcanic eruptions. We have been developing near-real-time volcanology based on the erupted materials in an early eruption stage.
2) Automation of textural analyses of erupted materials, Risk assessment of volcanic eruption based on eruption stratigraphy

Targeted Application(s)/Industry

Department of Earth Science, Graduate school of Science
NAKAMURA Michihiko, Professor Doctor of Science

[VSAT]

Advanced Wireless Information Technology

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Toward the realization of a ubiquitous and broad-band wireless network, we are actively engaged in the research work on dependable and low power consumption advanced wireless IT. We cover the whole technical fields from the lower to higher layers, i.e., signal processing, RF/Mixed signal device, antenna, MODEM and network technologies.As the studies on signal processing, RF/Mixed signal device and antenna technologies, we are developing RF/Millimeter-wave RF CMOS IC's, antenna integrated 3-dimensional system in package (SiP) transceiver modules, digital/RF mixed signal IC's.

Targeted Application(s)/Industry

If you are interested in a collaborative research work on above topics, please contact us via e-mail.

Research Institute of Electrical Communication
SUEMATSU Noriharu, Professor