Research Profiles

JP

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[Traffic monitoring]

Internet video streams have identities like fingerprints

 
 
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特徴・独自性
  • According to recent studies, each video that is streamed online has its own unique characteristic. The pattern of data that are sent through the network can vary from one encoding method to another and the change from scene to scene, which is a unique characteristic of each video. This research aims to identify video content in the network without looking at the data itself.
実用化イメージ

This research would be especially useful in preventing illegal distribution of television program such as illegal channel without violating user privacy. Another application would be to prevent confidential online meeting from leaking outside local enterprise network. In addition, it is also possible to investigate the circulation of a video content using method introduced by this work.

Researchers

Graduate School of Information Sciences

Nei Kato

[Transistor]

Development of Terahertz Semiconductor Devices Using Novel Nano-Heterostructures and Materials and their ICT Applications

 
 
 
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特徴・独自性
  • Terahertz coherent electromagnetic waves are expected to explore the potential application fields of future information and communications technologies. We are developing novel, ultra-broadband integrated signal-processing devices/systems operating in the terahertz frequency regime employing novel semiconductor nano-heterostructures and materials. We are challenging to develop room-temperature operating coherent and intense laser transistors and fast-response and highly sensitive detectors working for the next-generation beyond-5G terahertz wireless communications as well as safety and security terahertz imaging applications.
  • A. Ultimately-fast terahertz transistors utilizing graphene, carbon-based new material, and compound semiconductor heterojunction material systems:
  • Graphene-based novel terahertz photonics devices, breaking through the limit on conventional technology. Recently we have succeeded in single-mode terahertz lasing in a dual-gate graphene-channel laser transistor device at 100K. Moreover, we have succeeded in room-temperature terahertz coherent amplification in a dual-grating-gate graphene channel transistor promoted by current-driven graphene Dirac plasmon instability. The obtained maximal gain of 9% is four times as high as the quantum efficiency limit when terahertz photons interact directly with graphene electrons without excitation of graphene plasmons. These will be big steps towards realization of an intense, room-temperature operating graphene plasmonic terahertz laser transistors.
  • B. Frequency-tunable plasmon-resonant terahertz emitter and detectors and metamaterial circuits:
  • By using an original dual-grating-gate high-electron mobility transistor (DGG-HEMT) structure with InP-based material systems record-breaking ultrahigh-sensitive detection of terahertz radiation have been realized at room temperature.
実用化イメージ

By making full use of these world-leading device/circuit technologies, we are exploring future ultra-broadband 6G- and 7G-class wireless communication systems as well as spectroscopic/imaging systems for safety and security. We hope to conduct collaborative research with a willing company for a practical application of this technology in industry.

Researchers

Research Institute of Electrical Communication

Taiichi Otsuji

[Transition metal-free]

Colorful titanium oxide pigments without transition metals

概要

Colorful TiO2 Particle
https://www.t-technoarch.co.jp/data/anken_en/T19-849.pdf

従来技術との比較

Transition metal compounds are known to exhibit a wide variety of colors. Until now, it has been possible to color white titanium oxide by doping with transition metal ions, but it is difficult to avoid biotoxicity derived from transition metals.

特徴・独自性
  • In the present invention, titanium oxide inorganic pigments that do not contain transition metals and have various colors such as white, yellow, red, gray, green, purple, black, and skin color have been realized.
実用化イメージ

New applications of titanium oxide pigments are expected in the cosmetics field, where biotoxicity is an issue.

Researchers

Institute of Multidisciplinary Research for Advanced Materials

Yin Shu

[translational research]

Establishment of Minimally Invasive Cell Therapy for Diabetes by Introducing Interdisciplinary Approach

 
 
 
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特徴・独自性
  • The islet transplantation is the ideal "minimum invasive" cell transplant therapy for the severe diabetic patients who are suffering with controlling the blood glucose levels. In this project, we try to have a cross organization among the advanced technologies in islet transplantation as one of the typical cases. Our chief objective is to construct the center of medical cell-engineering therapy as successful examples in Tohoku University. We are convinced that technical innovation through this project could contribute much more to the activation of medical industry based upon cell therapy.
実用化イメージ

We have already established effective academic-industrial alliances regarding our several projects including a development of new type of cell-isolation enzyme. However, we are still looking for possible candidates concerning a special device for cell transplantation and medical grade-pathogen free animals.

Researchers

Graduate School of Medicine

Masafumi Goto

Clinical application of pulsed jet device to achieve maximal resection of the lesion and functional preservation

 
 
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特徴・独自性
  • Maximal resection and functional preservation, are often conflicting, but are both important factors to improve patient’s quality of life. Pulsed jet system is designed to achieve this goal by removing lesions without impairing small diameter vessels (100 μm - ). Standardization and specialization of surgical procedures is expected to achieve more easily compared to conventional surgical device using pulsed jet system. We have already reported significant increase of tumor removal rate, significant reduction of intraoperative blood loss and operation time in difficult lesions in the vicinity of sella turcica and skull base through expanded transsphenoidal approach. The system can eject small amount ( - 2 μl) of high speed liquid (- 50 m/s) for minimally invasive surgery, such as endoscopic, catheter, and microscopic surgery. The system is now under stage to expand clinical application outside the field of neurosurgery, and we are expecting new collaboration who can deal with increasing safety, effectiveness, differentiation from conventional instruments, accessibility.
実用化イメージ

Researchers

Administrative Staff

Teiji Tominaga

[Transmission electron microscopy]

Nano-Scale Total-Analysis Based on TEM

 
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特徴・独自性
  • Our lab develops accurate nanometer scale characterization methods of crystal structures by convergent-beam electron diffraction (<strong>CBED</strong>) and electronic structures by electron energy-loss spectroscopy (EELS) and soft-X-ray emission spectroscopy (<strong>SXES</strong>) for evaluating new functional materials. For performing crystal structure studies, we developed a new Ω-filter electron microscope and a refinement soft-ware, which can perform not only atom positions but also electrostatic potential and charge distributions. For electronic structure studies, a high-resolution EELS microscope and SXES instruments were developed.
実用化イメージ

Collaborated research of Local structures (symmetry, polarity, lattice defects) by CBED and electronic structures (bandgap, dielectric property and chemical state) by EELS and SXES on semiconductors, metals and dielectric materials are acceptable. Instructions of those analysis methods are also acceptable.

Researchers

Institute of Multidisciplinary Research for Advanced Materials

Masami Terauchi

[transparent]

newGlass that conducts heat well

 
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概要

We aim to give high thermal conductivity to glass, which is known as a material that does not conduct heat well, and to apply it to new fields.

従来技術との比較

If mixed with a high thermal conductive material, glass can be a good conductor of heat. However, all the advantages of glass, such as transparency and freedom of molding, are lost. In this research, we succeeded in developing a transparent glass with high thermal conductivity that retains its glassiness by adopting the strategies of high thermal conductivity MgO deposition and refractive index matching.

特徴・独自性
  • Transparent
  • Free molding
  • Thermal conductivity ~ 3 W/(m K) [300% of that of window glass]
実用化イメージ

Heat dissipation management using glass [heat dissipating glass substrates, lenses, fibers, etc.]

Researchers

Graduate School of Engineering

Nobuaki Terakado

[Transport]

Development of next-generation sterilization method by a plasma flow at atmospheric pressure

 
 
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特徴・独自性
  • Plasma sterilization has been developed as an alternative sterilization method due to its chemical activity, operation at low temperature and atmospheric pressure, low power consumption, low cost and safety. We have studied a mechanism of chemical species generation and transport in a plasma flow and, the sterilization efficacy and mechanism for several plasma sources at atmospheric pressure, such as a microwave plasma flow, a dielectric barrier discharge in a tube and a water vapor plasma flow. We already clarified that the damages of outer membrane and destructions of the cytoplasmic membrane of Escherichia coli by exposure to the microwave plasma flow. Fig. 1 shows the effect of plasma exposure on the E. coli. When the E. coli was exposed to the plasma, the height of the E. coli decreased and the potassium leakage of cytoplasmic material increased. For sterilization in a tube, we also clarified that an induced flow in the narrow tube by DBD transports chemical species and sterilize the whole inside surface of a tube as shown in Fig. 2. We hope to conduct collaborative research with a willing company for a practical application of this technology in industry.
実用化イメージ

Researchers

Institute of Fluid Science

Takehiko Sato

[Transport control]

Transport Control of Semiconductor Quantum Structures and Highly Sensitive NMR

 
 
 
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特徴・独自性
  • Highly-sensitive NMR technique has been developed by manipulation polarization of nuclear spins via control of transport characteristics in GaAs and InSb quantum structures. This highly-sensitive NMR can be applied to two-dimensional and nanostructures. Furthermore, ideal gate controllability has been demonstrated in InSb quantum structures with Al2 O3 dielectrics. More importantly, the concept of generalized coherence time was introduced, where noise characteristics felt by nuclear spins can be measured including their frequency dependence. This concept will bring about a change in all nuclear-spin related measurements.
実用化イメージ

Next generation InSb devices based on good gate controllability. Various nuclear-spin based measurements and NMR utilizing the concept of generalized coherence time. Highly-sensitive NMR is now important for fundamental physics studies. In the future, it will contribute to quantum information processing.

Researchers

Center for Science and Innovation in Spintronics

Yoshiro Hirayama

[Transport Phenomena]

Quantum and Molecular Dynamic Simulations of Transport Phenomena in Fuel Cell

 
 
 
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特徴・独自性
  • It is necessary to grasp nanoscale transport phenomena of materials in polymer electrolyte fuel cell to improve its performance. In our laboratory, nanoscale transport phenomena are analyzed by large scale molecular dynamics simulations using a supercomputer system. As the present theme, the dependence of the materials or structures of polymer electrolyte membrane on the ability of proton transfer(Fig. 1), the ability of proton transfer or oxygen permeability of ionomer in catalyst layer(Fig. 2), and the mechanism of transport phenomena of a water droplet in a nano pore in gas diffusion layer or micro porous layer(Fig. 3), are analyzed in detail.
実用化イメージ

These research can be applied to the analysis of flow field in devices which have nanoscale structure, for instance, fabrication process of semiconductor, friction phenomena of such nanoscale devices or next generation batteries, as well as the field of fuel cell.

Researchers

Institute of Fluid Science

Takashi Tokumasu

[treatment]

Development and evaluation of various inhibitors and disinfectants for SARS-CoV-2

 
 
 
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特徴・独自性
  • Using the infectious SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2), we are evaluating and developing new therapeutic drug candidates as well as evaluating disinfectants. Further analyses such as mechanism of action and resistance may be applicable. Other pathogens, including influenza virus and drug-resistant bacteria, will be examined upon request and discussion. Through joint and collaborative research with domestic and overseas pharmaceutical companies and related companies, we have experience of their clinical application including basic research.
実用化イメージ

We support development and evaluation of various inhibitors and disinfectants for variants of SARS-CoV-2 as well as wild type.

Researchers

International Research Institute of Disaster Science

Eiichi Kodama

[tribology]

Development of Fall-Prevention Footwear Based on Mechanical Analysis of Slip-Related Falls

 
 
 
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特徴・独自性
  • The number of fatalities due to falling accidents indoor/outdoor has increased in Japan as well as in other advanced countries. The fatalities due to falling accidents in a year have exceeded those due to traffic accidents in Japan recently. Because more than 80% of the fatalities are elderly people, it is considered an urgent issue to prevent their falling. We have conducted researches on falling during walking due to induced slip, in the contact interface of shoe sole and floor, through tribological and biomechanical approaches. We clarified the required values of static friction coefficient (figure 1), between shoe sole and floor, and how to gait to prevent slipping through kinetic analysis of gait. We also succeeded in the development of a unique footwear outsole having the high-grip property (figure 2) and high slip-resistant concrete pavement blocks (figure 3) through the collaboration with regional companies. We have recently conducted research and development of footwear that is able to prevent falls due to balance loss after slipping.
実用化イメージ

Products for fall prevention in daily life or in work site. Evaluation of slip resistance of footwear and floor materials.

Researchers

Graduate School of Engineering

Takeshi Yamaguchi

newDevelopment of a Numerical Prediction System for Sliding Part Wear and Seizure Occurrence Portions

 
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概要

Focusing on the lubricant film flow with phase change between the engine piston pin and connecting rod small end, we developed a new multiphase fluid-structure coupled analysis method that takes into account elastic deformation of the structure and flow path changes and developed a simulation prediction method for tribological properties under high load conditions. The simulation prediction method for tribological properties under high load conditions has been created. As a result, we succeeded in simulation prediction of the wear/seizure generating areas in sliding parts. We discovered that the peculiar deformation behavior of the components is the cause of wear/seizure.

従来技術との比較

It has been thought that computational prediction is impossible to verify the wear and seizure locations in fluid lubrication. Still, this study succeeded in the simulation prediction of wear and seizure locations in sliding parts.

特徴・独自性
  • Numerical prediction of the wear and seizure locations in the sliding parts of engine piston pins was successfully performed.
  • The bow-like deformation of the piston pin was identified as the cause of mechanical contact and seizure at the connecting rod edge.
  • A three-dimensional multiphase fluid-structure coupled analysis method has been successfully developed, considering the piston pin's elastic deformation and connecting rod and thin-film cavitation1 lubrication with unsteady flow path changes.
実用化イメージ

This research method applies to automotive engines and all sliding component elements using fluid lubrication. It contributes to damage prediction and the development of safety guidelines for transportation and industrial machinery components, enabling the optimal design of components.

Researchers

Institute of Fluid Science

Jun Ishimoto

[TSLP]

Regulation of TSLP Production in Keratinocytes

 
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特徴・独自性
  • Thymic stromal lymphopoietin(TSLP)has been focused as a master switch for allergy. We established a mouse keratinocyte cell line which constitutively and highly produces TSLP. This cell line will be useful to find the inhibitor of TSLP production and to study biochemical features of production and action of TSLP. The inhibitor of TSLP production might be used as an external or an inhalation drug, indicating low probability of causing a decrease in immune competence.
実用化イメージ

By using this cell line, we expect we can conduct effective collaborative research in medical fields. For examples, the cell line is useful for analysis of TSLP production and functions, development of inhibitors of TSLP production, and detection of immunotoxic compounds.

Researchers

Graduate School of Pharmaceutical Sciences

Noriyasu Hirasawa

[Tsunami]

[Tsunami Engineering]

[tumor-specific]

Production of Tumor-Specific Monoclonal Antibodies

 
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特徴・独自性
  • Podoplanin (PDPN/Aggrus/T1α), a platelet aggregation-inducing mucin-like sialoglycoprotein, is highly expressed in many cancers and normal tissues. A neutralizing monoclonal antibody (mAb; NZ-1) can block the association between podoplanin and C-type lectin-like receptor-2 (CLEC-2) and inhibit podoplanin-induced cancer metastasis, but NZ-1 reacts with podoplanin-expressing normal cells such as lymphatic endothelial cells. Recently, we established a platform to produce cancer-specific mAbs (CasMabs). The newly established LpMab-2 mAb reacted with podoplanin-expressing cancer cells but not with normal cells, as shown by flow cytometry and immunohistochemistry; therefore, LpMab-2 is an anti-podoplanin CasMab that is expected to be useful for molecular targeting therapy against podoplanin-expressing cancers.
実用化イメージ

We can produce cancer-specific mAbs (CasMabs) against all membranous proteins. CasMabs are expected to be useful for molecular targeting therapy without side effects.

Researchers

Graduate School of Medicine

Yukinari Kato

[tunnel magnetoresistance]

Development of High Sensitive Magnetic Sensor Operating at Room Temperature with Tunnel Magnetoresistance Devices

 
 
 
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特徴・独自性
  • Recently, many tunnel magnetoresistance devices with high magnetoresistance effect are reported. These are expected to be applied to high sensitive magnetic sensors. There are many magnetic sensors with variety of the mechanism, in order to meet the demand of the very wide range of sensing magnetic field. However, there is no magnetic sensor which has high sensitivity, easy to use, operation at room temperature and low cost. Only a magnetic sensor with tunnel magnetoresistance devices can satisfy all the demand in principle. As the device has very wide range of the sensing magnetic field, it can be designed for any demand to the sensors.
実用化イメージ

For example, this device can sense a bio-magnetic field easily at room temperature, so that it could be replaced SQUID device, which is popular now but is very expensive and not easy to use personally. Therefore, by using this device, we expect we can conduct effective collaborative research in medical field.

Researchers

Graduate School of Engineering

Yasuo Ando

[Two-dimensional system]

Transport Control of Semiconductor Quantum Structures and Highly Sensitive NMR

 
 
 
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特徴・独自性
  • Highly-sensitive NMR technique has been developed by manipulation polarization of nuclear spins via control of transport characteristics in GaAs and InSb quantum structures. This highly-sensitive NMR can be applied to two-dimensional and nanostructures. Furthermore, ideal gate controllability has been demonstrated in InSb quantum structures with Al2 O3 dielectrics. More importantly, the concept of generalized coherence time was introduced, where noise characteristics felt by nuclear spins can be measured including their frequency dependence. This concept will bring about a change in all nuclear-spin related measurements.
実用化イメージ

Next generation InSb devices based on good gate controllability. Various nuclear-spin based measurements and NMR utilizing the concept of generalized coherence time. Highly-sensitive NMR is now important for fundamental physics studies. In the future, it will contribute to quantum information processing.

Researchers

Center for Science and Innovation in Spintronics

Yoshiro Hirayama

[tyhoon]

Prediction and evaluation of future thermal and wind environments based on CFD, and planning of urban environments adaptable to future climate

 
 
 
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特徴・独自性
  • Numerical simulations of the physical environment of urban outdoor spaces are conducted to predict the physical environment, such as temperature, humidity, wind, and pollutant concentration, and field measurements are conducted to understand the actual physical environment. In addition, the future outdoor environments and heat stroke risks due to global warming are predicted and evaluated.
    Furthermore, the impacts of urban morphology (building shape and layout, street trees, etc.) on the adaptation to severe heat in summer and rare typhoons and floods are evaluated quantitatively.
実用化イメージ

Numerical analysis is used to quantitatively evaluate the "merits and demerits" of designing buildings, planning city blocks and urban areas, and introducing various heat control technologies on the wider thermal environment and the formation of wind ventilation paths, as well as the adverse effects of typhoons and other disasters. The materials for making decisions on whether or not to introduce these technologies are provided.

Researchers

Graduate School of Engineering

Yasuyuki Ishida

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