"P" Keywords - 87 Result(s)

 P

[polymer resist/mold material]

Photo-Functional Advanced Materials for Nanofabrication by Nanoimprint Lithography

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特徴・独自性
  • Nakagawa group has dedicated to pursue scientific principles for molecular control of interface function occurring at polymer/other material interfaces and to put them into practice in nanoimprint lithography promising as a next generation nanofabrication tool. We are developing advanced photo-functional materials such as sticking molecular layers for "fix by light", UV-curable resins and antisticking molecular layers for "preparation by light", fluorescent resist materials for "inspection by light", and hybrid optical materials "available to light" and new research tools such as mechanical measurement systems to evaluate release property of UV-curable resins.
実用化イメージ

Our research aims at creating new devices to control photon, electron, and magnetism.

Researchers

Institute of Multidisciplinary Research for Advanced Materials

Masaru Nakagawa

[population]

Economics of Aging

特徴・独自性
  • I investigate on the economics of aging, the optimal social welfare policy, low fertility and so on not based on the historical and systematic approach but based on the neo-classical economic theory. I also use econometric method and statistical approach. I often estimate the future projections of the population, public finance, magnitude of private markets, the results of public policies.
  • I also research on the comparative studies on East Asia (Japan, China, Korea, Taiwan) and European (especially Scandinavian countries). I provide statistic data and information on the economic and political systems on the aging in Japan.
実用化イメージ

The future estimation on the financial status , market caused by low fertility and aging. The effective management of the medical institutions, social welfare systems, gender equality societies for the central and local government, research institutions, public enterprises, and financial Institutions.

Researchers

Graduate School of Economics and Management

Hiroshi Yoshida

[population dynamics]

Mathematical Biology

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特徴・独自性
  • Principal subject of our study is the mathematical model analysis to make clear or present the point at issue for scientific discussion about real biological/social phenomena, or to promote the advanced theoretical research: what theoretical problem about target phenomenon is treated, how the problem is mathematically modeled, what mathematical analysis is applied for the model, and how the mathematical result is lead to the discussion in biological/social science.
実用化イメージ

Researchers

Graduate School of Information Sciences

Hiromi Seno

[positron emission tomography]

Functional and Molecular Imaging with Positron Emission Tomography (PET)

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特徴・独自性
  • Using positron emission tomography (PET), we can measure the regional metabolism, perfusion and signal transmission between neurotransmitters and receptors in various organ systems of living humans and animals, such as the brain and heart. Recent technical developments have shown that the mind, or at least some parts of it, can be demonstrated by "imaging".
実用化イメージ

Our group has had considerable achievements in clinical research on drug effects and side effects, elucidation of underlying mechanism of alternative and complementary therapies, as well as exercise physiology.

Researchers

Research Center for Accelerator and Radioisotope Science

Manabu Tashiro

[Powder metallurgy]

Microwave Processing of Functional Inorganic Materials

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特徴・独自性
  • Microwave processing is one of the attractive fields in recent materials processing. We perform various materials processing using non-equilibrium reaction field induced by microwave and/or ultrasonic irradiation. The topic contains powder metallurgy, nitride coatings, synthesis of new functional materials, fabrication of nanoparticles, etc. Recently we have developed a new TiN coating method using our microwave irradiation equipment operated at a frequency of 2.45 GHz. The method is simple but applicable to various substrates with complex shape. This method can be applied to various nitride coatings and will open a new coating technology in many fields of applications.
実用化イメージ

The major targets of TiN coatings are for cutting tools, ball bearings, dental implants, die and mold for stamping, and ornaments. The newly developed method makes it possible to perform nitride coatings within a short time using a standard microwave heating equipment. We hope to conduct collaborative research with a willing company for a practical application of these technology.

Researchers

Administrative Staff

Hirotsugu Takizawa

[precision measurement]

Development of Sensors and Measuring Systems for Ultra-Precision Manufacturing and Nanomanufacturing

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特徴・独自性
  • The research is being focused on measurement of surface forms of precision workpieces and stage motions of precision machines, which are important items for ultra-precision manufacturing and nanomanufacturing. Optical sensors are being developed for measurement of angle and displacement, which are fundamental quantities for manufacturing. Technologies for improvement of the sensor sensitivity and bandwidth, reduction of the sensor size as well as new multi-axis sensing methods are being The research is being focused on measurement of surface forms of precision workpieces and stage motions of precision machines. Optical sensors are being developed for measurement of angle and displacement. A number of scanning-type measuring systems for precision measurement of surface forms and stage motions are also being developed. Error separation algorithms and systems for straightness and roundness, which are the most fundamental geometries treated in ultra-precision manufacturing, are being investigated. Novel systems based on scanning probe microscopy are under development for micro- and nano-structures as well as freeform optics in responding to new and important challenges from ultra-precision manufacturing and nanomanufacturing.
実用化イメージ

The multi-axis optical displacement and angle sensors developed in the laboratory are expected to measure motions of semiconductor/IC manufacturing and inspection equipment, precision machine tools, ultra-precision measuring instrument. The surface profile measurement systems are expected t play an important role in ultra-precision manufacturing and nanomanufacturing industries.

Researchers

Graduate School of Engineering

I Ko

[preference]

Food Palatability, Product Usability, and Preference; An Approach from Psychology and Neuroscience.

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特徴・独自性
  • My research interest is peoples' perception of external stimulus. Based on these researches and our knowledge, I can offer you an idea of the products that give consumers satisfaction. Also on the basis of psychological and neuro-scientifc experiences and knowledges, I can offer you a transdisciplinary approaches on human perception, cognition, emotion and decision making.
実用化イメージ

Marketing and developing of the products such as foods, beverages, fabric softeners, perfumes, body deodorants etc. The knowledges and research tools are also useful in regulating the malodor in the air pollution, in developing the public services and in elevating public quality of life.

Researchers

Graduate School of Arts and Letters

Nobuyuki Sakai

[preventive medicine]

Quantitative Evaluation of the Baroreflex Sensitivity of the Heart and Artery

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特徴・独自性
  • Metabolic syndrome is an important view point, when we consider the preventive medicine. Hypertension is one of the most important points to prevent the cardiovascular events. However, there is no method to measure the baroreflex sensitivity of the artery in the patients with hypertension. Tohoku University had invented the new method to evaluate the baroreflex sensitivity of the heart and artery (JP Patent No.4789203).
実用化イメージ

By the use of this machine, the baroreflex sensitivity of an artery in the patients can easily be measured noninvasively. It enables to predict the occurrence of hypertension and evaluate the therapy of hypertension easily, while allowing prevention of the cardiovascular events.

Researchers

Institute of Development, Aging and Cancer

Tomoyuki Yambe

[printing process]

Advanced Technology on Flexible Liquid Crystal Displays

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特徴・独自性
  • Flexible liquid crystal displays using thin plastic film substrates instead of glass substrates contained in current liquid crystal displays, are bendable, thin, lightweight, and do not crack, and generate new usage styles and human interfaces due to their excellent storability and portability. We have been researching the basic technologies for large-screen and high-quality flexible displays using functional organic materials including liquid crystal and polymer, so that anyone can enjoy fertile information services.
実用化イメージ

We hope to conduct collaborative research with a willing company in industry, for development and practical application of the advanced flexible display technologies.

Researchers

Graduate School of Engineering

Hideo Fujikake

[Privacy]

Blockchain-based Approachs for High Secure P2P-type Decentralized Cloud Storage and Practical Smart Contract for Trading Personal Data

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特徴・独自性
  • We are developing a decentralized P2P (Peer to Peer) type cloud storage that realizes innovative level of security by use of surplus storages of P2P nodes with the Blockchain technology. The developed storage can avoid the risk of large-scale information leakage of stored data due to the weakness of the central server. By using our cryptographic currency for rewards and usage fees in the storage, fair storage usage of all users can also be achieved.
  • In addition, We are developing a unique smart contract technology for practical decentralized trading of personal data among an unspecified number of users.
実用化イメージ

We hope to conduct collaborative researches with companies developing Bitcoin 2.0 type application (e.g. smart contract, Fintech) based on the Blockchain technology, the Internet of Things (IoT) technology, Medical Database for practical use.

Researchers

Center for Data-driven Science and Artificial Intelligence

Masao Sakai

[probe synthesis]

Synthesis of Biologically Active Cyclodepsipeptide Natural Products

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特徴・独自性
  • Cyclodepsipeptide natural products include optically active hydroxy acids as well as various unnatural amino acids and exhibit a variety of biological activity depending on the peptide sequence, chirality, and selection of the hydroxy acids. Structure-activity relationships of a synthetic library of natural products could give us significant information of not only biologically important moieties but also intact positions in the biologically active small molecules. On the basis of the former information, more potent compounds and/or peptide mimetics can be designed. The latter information can also be important for making a molecular probe that is used for exploration of a target molecule.
実用化イメージ

We study for combinatorial synthesis of natural product analogues using solid-phase.

Researchers

Graduate School of Pharmaceutical Sciences

Takayuki Doi

[Probiotics]

Gastroenteritis virus-binding enteric bacteria for probiotics

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特徴・独自性
  • We have found enteric bacteria that can capture gastroenteritis viruses, such as norovirus and rotavirus, through histo-blood group antigen (HBGA)-like substances. These HBGA-positive bacteria give a significant impant on the ecology of gastroenteritis viruses in human body and in environments.
実用化イメージ

Since gastroenteritis virus-binding bacteria can affect the viral infection capability to host cells, these bacteria and produced HBGA-like substances are available in probiotics application.

Researchers

Graduate School of Engineering

Daisuke Sano

[Process equipment]

Development of Advanced Device and Process Technologies and New Image Sensors

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特徴・独自性
  • Toward the ultimate performances of image sensors, advanced research activities are being conducted that cover a wide range of technology fields from cleanroom infrastructure, materials, process equipment, process, device, circuit, assembly, signal processing, measurement/evaluation and reliability. Following technologies have been successfully commercialized:
  • A fast and accurate measurement technology of electrical characteristics for over 1 million transistors
  • A wide dynamic range CMOS image sensor technology capturing images over five decade brightness ranges
  • An ultra-fast CMOS image sensor technology with 10 million frames/sec
実用化イメージ

Followings are available for industry collaborators:
A. 200mm-diameter-wafer silicon device fabrication utilizing the ultra-clean facility including wafer mutual fabrication processing between device manufacturers.
B. Process technology development and various kinds of analyses.
C. Development of new image sensors.

Researchers

New Industry Creation Hatchery Center

Shigetoshi Sugawa

[product usability]

Food Palatability, Product Usability, and Preference; An Approach from Psychology and Neuroscience.

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特徴・独自性
  • My research interest is peoples' perception of external stimulus. Based on these researches and our knowledge, I can offer you an idea of the products that give consumers satisfaction. Also on the basis of psychological and neuro-scientifc experiences and knowledges, I can offer you a transdisciplinary approaches on human perception, cognition, emotion and decision making.
実用化イメージ

Marketing and developing of the products such as foods, beverages, fabric softeners, perfumes, body deodorants etc. The knowledges and research tools are also useful in regulating the malodor in the air pollution, in developing the public services and in elevating public quality of life.

Researchers

Graduate School of Arts and Letters

Nobuyuki Sakai

[productivity improvement]

Improvement of Seed Production by Using Reproductive Trait in Crops, Especially, Rice and Cruciferous Crops

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概要

The recent spate of extreme weather events is threatening to reduce crop seed and fruit production. We have identified a catalog of genes that respond under low and high temperature stress, and will construct a system that enables production under temperature stress through genome editing and other methods.

従来技術との比較

In addition to conventionally used genetic recombination methods, genome editing technology has made it possible to modify genes that can be used for practical purposes.

特徴・独自性
  • Crops are important for food, environment recovery, energy production, and amenity activity for human being. For improvement of crop seed production, the breeding of crops having environmental stress, is important. Especially the developmental stage from pollination to fertilization is quite weak for these environmental stresses. Thus, by breeding of reproductive trait, we will establish the high productivity and quality of crop seeds. From our research, we found several stress-tolerant genes. We already started the research by both basic and applied level.
実用化イメージ

For application, we evaluated by taking prize for application in 2001. And our basic data has been published in international Journal, "Nature" and "Science". If anyone is interested in these genes, we hope to conduct to collaborative research for establishing the useful breeding lines.

Researchers

Graduate School of Life Sciences

Masao Watanabe

[Programming Models]

Supercomputing for enabling large-scale advanced simulations

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特徴・独自性
  • As modern supercomputers are getting larger and more complicated, it is not so easy to exploit their potential performance. It is necessary to develop a simulation code with considering various factors for both hardware and software reasons, and hence expert knowledge and experiences about supercomputing are often needed to achieve high actual performance. Our research interests focus on shaping future supercomputing systems and their applications, especially system software technologies for effectively using the future supercomputers. Also we are always exploring how to make good use of the state-of-the-art hardware and software technologies in order to enable unprecedented-scale and more advanced simulations.
  • From beginning (apply for use of our supercomputer) to end (get a solution), we can consistently support developing large-scale practical simulation, which is feasible only by using the supercomputer. As a supercomputing center, we have a long history of parallelizing and accelerating a lot of practical simulation programs. In addition, we are looking for research collaborators who are interested in streamlining and/or facilitating large-scale scientific software development.
実用化イメージ

Researchers

Cyberscience Center

Hiroyuki Takizawa

[Prolyl hydroxylase]

Development of PHD-Targeted Drug for Ischemic Injury

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特徴・独自性
  • All the living organisms generate energy from molecular oxygen to maintain their own lives. Once the concentration of oxygen falls down, life activity gets severely hampered and it could sometimes cause death. Typical examples that are related to local hypoxia are ischemic heart disease, stroke and kidney disease.
  • We focus on the function of prolyl hydroxylase (PHD) as a sensor to detect the hypoxia, and we are developing drugs to treat ischemic injury by controlling hypoxia.
実用化イメージ

Currently, we have several compounds that inhibit the PHD. We want to commercialize in conjunction with pharmaceutical companies in Japan and overseas, advancing our non-clinical studies for clinical development.

Researchers

Graduate School of Medicine

Toshio Miyata

[protein]

Imaging and photoregulation of biological functions

特徴・独自性
  • To properly understand the functions of biomolecules, it is essential to observe them under physiological conditions where the interactions with other biomolecules are preserved. Therefore, we are developing new functional molecules using both organic chemistry and protein science approaches, and working on the visualization and optical control of biomolecules and their functions. Especially, we have developed fluorescent probes that quantitate the concentration of biomolecules or ions in subcellular regions such as organelles and caged compounds and photoswitches that optically manipulate the biomolecular functions.
実用化イメージ

Researchers

Institute of Multidisciplinary Research for Advanced Materials

Shin Mizukami

[protein labeling]

Imaging and photoregulation of biological functions

特徴・独自性
  • To properly understand the functions of biomolecules, it is essential to observe them under physiological conditions where the interactions with other biomolecules are preserved. Therefore, we are developing new functional molecules using both organic chemistry and protein science approaches, and working on the visualization and optical control of biomolecules and their functions. Especially, we have developed fluorescent probes that quantitate the concentration of biomolecules or ions in subcellular regions such as organelles and caged compounds and photoswitches that optically manipulate the biomolecular functions.
実用化イメージ

Researchers

Institute of Multidisciplinary Research for Advanced Materials

Shin Mizukami

[Protein Structure Analysis]

Development and evaluation of various inhibitors and disinfectants for SARS-CoV-2

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特徴・独自性
  • Using the infectious SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2), we are evaluating and developing new therapeutic drug candidates as well as evaluating disinfectants. Further analyses such as mechanism of action and resistance may be applicable. Other pathogens, including influenza virus and drug-resistant bacteria, will be examined upon request and discussion. Through joint and collaborative research with domestic and overseas pharmaceutical companies and related companies, we have experience of their clinical application including basic research.
実用化イメージ

We support development and evaluation of various inhibitors and disinfectants for variants of SARS-CoV-2 as well as wild type.

Researchers

International Research Institute of Disaster Science

Eiichi Kodama