"S" Keywords - 161 Result(s)
S
[Si]
A novel crystal growth via controlling an energy relationship between crystal and melt with applying an electric fieldFeaturesThis lab is concerned with the novel approach mainly for the growth from melt by studying the relationship between the interface dynamics during growth and properties of grown crystals. Special interests lie in the growth of new crystals via the imposition of an interface-electric field. Nano-scaled control of crystal growth is executed in an electric double layer of ~nm thickness that is induced by applying an external electric field on the growth interface. Some of our growth results brought by applying an electric field are; |
[Si semiconductors]
Development of Interconnect Materials and Processes for High Performance and High Reliability Electric DevicesFeaturesElectronic products can be operated not only by semiconductors but also by metal interconnections attached to the semiconductors. Required properties for the metal interconnections are ohmic contact, diffusion barrier property, adhesion with semiconductors, and low resistivity, corrosion resistance, process reliability. Our group has committed ourselves to develop new metals and processes to meet the needs of wide-ranged device producers with consideration of cost performance. Topics of our research include (1) Cu alloys to self-form a diffusion barrier layer in multilayer interconnection of Si devices, (2) Cu alloys to form a reaction-doping layer in IGZO oxide semiconductors, (3) Nb alloys to achieve mechanical and thermal reliability with good ohmic property for SiC power devices, (4) Cu alloys for transparent conductive oxide such as ITO, (5) screen-printable Cu paste lines for solar cells, etc.. Targeted Application(s)/IndustryOur research efforts are targeted at metallization and interconnections for advanced LSI, flat panel displays, touch panels, power modules, solar cells, and other electronic devices. Collaborators include material producers, equipment vendors, and device producers in the entire value chain of electronic products. Department of Materials Science, Graduate School of Engineering
KOIKE Junichi, Professor
PhD
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[Sialadenitis]
Development of Recombinant Inbred Mice with a Genetic Predisposition to Collagen DiseaseFeaturesEleven strains of recombinant inbred (RI) mice derived from MRL/lpr and C3H/lpr mice were established. This RI is the only one in the world that randomly develops lesions such as nephritis, arthritis, sialadenitis, vasculitis, and production of autoantibodies in each strain. The genomes of the two strains of mice are randomly held in homozygous condition, and the phenotypes of each strain and the effects of administered drugs could be compared based on their genotype maps. It is possible to identify the regions of gene loci involved in the phenotype and drug sensitivity. Targeted Application(s)/IndustryDevelopment of diagnostic and therapeutic agents for autoimmune diseases. It can be applied to the elucidation of the mechanism of onset of immunological adverse events caused by immune checkpoint inhibitors and the development of drugs to prevent the onset of such events, and industry-academia collaboration with pharmaceutical companies, test reagent companies, etc. is possible. Graduate School of Biomedical Engineering
KODAMA Tetsuya, Professor
PhD (Engineering), PhD (Medicine)
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Development of McH-lpr/lpr-RA1 mouse, a study model that spontaneously develops severe autoimmune arthritis, vasculitis, and sialadenitisFeaturesMcH/lpr-RA1 mice are recombinant congenic mice descended from MRL/lpr and C3H/lpr mice and develop arthritis, vasculitis, and sialadenitis with high frequency and severity, with severe pannus formation similar to rheumatoid arthritis, polyarteritis nodosa, and Sjogren's syndrome. On the other hand, McH/lpr-RA1 mice do not develop systemic lymphadenopathy and severe nephritis as seen in MRL/lpr mice, so they are easy to breed and maintain and can be used for long-term drug administration experiments. Targeted Application(s)/IndustryDevelopment of diagnostic and therapeutic agents for collagen diseases. It can be applied to the elucidation of the mechanism of onset of immunological adverse events caused by immune checkpoint inhibitors and the development of drugs to prevent the onset of such events, etc. Industry-academia collaboration with pharmaceutical companies, test reagent companies, etc. is possible. Graduate School of Biomedical Engineering
KODAMA Tetsuya, Professor
PhD (Engineering), PhD (Medicine)
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[SiC power devices]
Development of Interconnect Materials and Processes for High Performance and High Reliability Electric DevicesFeaturesElectronic products can be operated not only by semiconductors but also by metal interconnections attached to the semiconductors. Required properties for the metal interconnections are ohmic contact, diffusion barrier property, adhesion with semiconductors, and low resistivity, corrosion resistance, process reliability. Our group has committed ourselves to develop new metals and processes to meet the needs of wide-ranged device producers with consideration of cost performance. Topics of our research include (1) Cu alloys to self-form a diffusion barrier layer in multilayer interconnection of Si devices, (2) Cu alloys to form a reaction-doping layer in IGZO oxide semiconductors, (3) Nb alloys to achieve mechanical and thermal reliability with good ohmic property for SiC power devices, (4) Cu alloys for transparent conductive oxide such as ITO, (5) screen-printable Cu paste lines for solar cells, etc.. Targeted Application(s)/IndustryOur research efforts are targeted at metallization and interconnections for advanced LSI, flat panel displays, touch panels, power modules, solar cells, and other electronic devices. Collaborators include material producers, equipment vendors, and device producers in the entire value chain of electronic products. Department of Materials Science, Graduate School of Engineering
KOIKE Junichi, Professor
PhD
|
[Side-Channel Attack]
Visual Computing with Secure ICT in the Big Data EraFeaturesOur study focuses on sensing, processing, recognition, understanding, and analysis of enormous visual data collected in real-world environments. We have invented a set of advanced techniques of sub-pixel image analysis using phase-based image matching. Potential applications include personal recognition using various biometric traits (e.g., face, fingerprint, palm print, finger knuckle print, iris, and medical radiographs), machine vision, multi-view 3D reconstruction, image database search, and medical image computing. We are also studying fundamental techniques for building secure ICT infrastructure for the big data era; our research interests include tamper-resistant cryptographic processing and biometrics-based secure remote authentication. Targeted Application(s)/IndustryWe can provide collaboration and information exchange services for industries and other research organizations in the fields of image processing, computer vision, information security, biometrics, LSI design, and embedded system technologies. Many researchers and engineers from various companies, universities, and research institutions have visited our laboratory regardless of their technology fields. Our staff at the Intelligent Information System (IIS) Research Center will welcome potential collaborators: info@iisrc.ecei.tohoku.ac.jp Graduate School of Information Sciences
AOKI Takafumi, Professor
Doctor of Engineering
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[Signal processing]
Study on Tactile/Touch Feeling SensorFeaturesTactile sense and the sense of touch are multiple combinations of fundamental sensations, such as smooth and rough, soft and hard, dry and wet, and hot and cold sensations. These sensations are described with the information on force, distortion, temperature, stickiness and oscillation. Targeted Application(s)/IndustryThe research is beneficial not only to life science but also to manufacturing fields. |
[silicon carbide]
Low-Temperature Synthesis of SiC Porous Bulk by Using NaFeaturesSiC ceramics is generally prepared at high temperature of 1200–2000ºC. We are able to prepare SiC at around 700ºC by using Na. Nano-powder of beta-type SiC was obtained from a mixture of Si and carbon powders in a Na melt. SiC porous ceramics were synthesized by heating mixtures of Si powder and carbon black at 700–900ºC in Na vapor. Biomorphic cellular SiC ceramics were formed by heating carbonized woods at 700 ºC with a Na-Si melt. Targeted Application(s)/IndustryApplications : SiC porous ceramics are used in a wide range of applications, such as filters for gas or molten metal, diesel particle filters, catalysis supports, and light-weight structural materials. Institute of Multidisciplinary Research for Advanced Materials
YAMANE Hisanori, Professor
Doctor of Science
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[Silicon Neural Probe]
Development of Biomedical Micro/Nano Integrated System Using LSI TechnologyFeaturesSemiconductor neural engineering is a discipline that uses semiconductor process/device/circuit technologies to further understand properties of neural systems and to create novel fusion systems of living body and machine. Targeted Application(s)/IndustryOne of the goals in this laboratory is to establish semiconductor neural engineering and develop biomedical micro/nano integrated systems. |
[Simulation]
Advanced Mobility Management Using Transport SimulationFeaturesThis laboratory has been developing transport simulation models and their support tools. Transport simulation that can appropriately analyze dynamically changing transport condition is requested to design and evaluate several management schemes. Two simulation models AVENUE and SOUND have been developed and used for quite a few practical applications: AVENUE is applied to a mid-size area including 20 to 30 intersections and SOUND is applied to a wider area such as to a whole Tokyo metropolitan region. Targeted Application(s)/IndustryPrivate companies, road authorities and traffic management organizations that are interested in the simulation technology could work together with us. |
High Performance Computer Architectures and their ApplicationsFeaturesMy research interests include the design and development of high-performance supercomputing systems and their applications. Targeted areas range from the key components of supercomputing systems, which include processor architectures, memory subsystems, network systems, task schedulers, and compilers, to high-performance multimedia processing algorithms such as photo-realistic computer graphics. Targeted Application(s)/IndustryCurrently I am conducting joint-research projects with several companies in the fields of high-performance computer architecture design and advanced simulation technologies for industrial design such as next-generation supercomputers and highly efficient and comfortable regional jets. Graduate School of Information Sciences
KOBAYASHI Hiroaki, Professor
Doctor of Engineering
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Simulation, Remote Sensing and Geoinformatics for Disaster ManagementFeaturesWith use of modern computing power, we develop a new framework to search and detect the impact of natural disaster by integrating real-time computing, damage/loss estimation models, remote sensing and geo-informatics. Targeted Application(s)/IndustryInnovation in disaster management and response can be expected by fusion of high-performance real-time disaster simulation, remote sensing and geo-informatics. International Research Institute of Disaster Science
KOSHIMURA Shunichi, Professor
Ph.D.
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Powder Processing Contributing to the Global Environmental ProtectionFeaturesMaterial properties and characteristics of the product as a raw material powder are dependent on the particle packing structure as well as the chemical composition. Sophisticated control of the powder processing such as mixing and grinding is strongly required. In our laboratory, we are creating the simulation method as a tool for controlling the powder processing and optimizing the powder process for achieving a resource-saving and energy-saving by the computer simulation. Targeted Application(s)/IndustryWe are conducting research on analysis/optimization of powder processing such as grinding, mixing, and packing by using simulation, metal recycle from urban mine through active utilization of mechanochemical effect, and generation of energy from biomass. Institute of Multidisciplinary Research for Advanced Materials
KANO Junya, Professor
Doctor of Engineering
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[simultaneous measurement of pressure and velocity]
Understanding and application of thermoacoustic phenomenaFeaturesAcoustic oscillations of a gas column in narrow flow channels can lead to various thermal phenomena such as production and amplification of acoustic power from heat and generation of low temperatures. We aim at understanding these thermoacoustic phenomena from experimental point of view, and developing heat engines that can operate without any moving parts like solid pistons. Targeted Application(s)/IndustryAcoustic prime mover can use various heat sources like industrial waste heat and sunlight. Acoustic cooler is a Helium-gas based heat pump that needs no Freon gases as a coolant. |
[sinensetin]
Drug Development for Fundamental Treatment of Alzheimer's DiseaseFeaturesBackground: Alzheimer's disease (AD) is a neurodegenerative disorder with a large unmet medical need. Recently, our pilot clinical study suggested the possibility that 1-year oral administration of decocted nobiletin-rich Citrus reticulata peel could be of benefit for improving the cognition of patients with AD, with the following pharmacological features: 1) this Kampo medicine includes a large amount of nobiletin that can rescue the memory impairment and prevents hippocampal amyloid beta accumulation in APP-Tg mice, as originally reported by us, and 2) the medicine reversed impaired learning and memory to a greater degree than nobiletin in animal, to which sinensetin, another constituent contributes in large part. Targeted Application(s)/IndustryOur research goal is discovery of the drugs for fundamental treatment of AD. I hope to conduct collaborative research with a willing company for a practical application of this technology in industry. Department of Pharmacotherapy, Graduate School of Pharmaceutical Sciences
YAMAKUNI Tohru,
PhD
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[single cell analysis]
Biological Application of Scanning Probe MicroscopeFeaturesWe have invented a unique method to non-invasively evaluate the quality of individual mammalian embryos based on oxygen consumption. A Pt microelectrode was scanned near the single embryo sample to obtain oxygen concentration profile. Respiration activity of single embryo was estimated based on spherical diffusion theory. Further, it was found that the respiration activities of individual embryos corresponded the developmental potential of the embryos. Independently, we have developed a procedure of mRNA quantification from single-cell based on SPM featuring multi-functional probes. Next, we are going to combine the two methods mentioned above for quality control of mammalian embryos and embryonic stem cells. Targeted Application(s)/IndustryOur methods will be applied for assisted reprodictive technoloy (ART), pancreatic islet transplantation, or animal breeding. |
[Sintering]
Microwave Processing of Functional Inorganic MaterialsFeaturesMicrowave processing is one of the attractive fields in recent materials processing. We perform various materials processing using non-equilibrium reaction field induced by microwave and/or ultrasonic irradiation. The topic contains powder metallurgy, nitride coatings, synthesis of new functional materials, fabrication of nanoparticles, etc. Recently we have developed a new TiN coating method using our microwave irradiation equipment operated at a frequency of 2.45 GHz. The method is simple but applicable to various substrates with complex shape. This method can be applied to various nitride coatings and will open a new coating technology in many fields of applications. Targeted Application(s)/IndustryThe major targets of TiN coatings are for cutting tools, ball bearings, dental implants, die and mold for stamping, and ornaments. The newly developed method makes it possible to perform nitride coatings within a short time using a standard microwave heating equipment. We hope to conduct collaborative research with a willing company for a practical application of these technology. Department of Applied Chemistry, Graduate School of Engineering
TAKIZAWA Hirotsugu, Professor
Doctor of Engineering
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[Sjogren's syndrome]
Development of McH-lpr/lpr-RA1 mouse, a study model that spontaneously develops severe autoimmune arthritis, vasculitis, and sialadenitisFeaturesMcH/lpr-RA1 mice are recombinant congenic mice descended from MRL/lpr and C3H/lpr mice and develop arthritis, vasculitis, and sialadenitis with high frequency and severity, with severe pannus formation similar to rheumatoid arthritis, polyarteritis nodosa, and Sjogren's syndrome. On the other hand, McH/lpr-RA1 mice do not develop systemic lymphadenopathy and severe nephritis as seen in MRL/lpr mice, so they are easy to breed and maintain and can be used for long-term drug administration experiments. Targeted Application(s)/IndustryDevelopment of diagnostic and therapeutic agents for collagen diseases. It can be applied to the elucidation of the mechanism of onset of immunological adverse events caused by immune checkpoint inhibitors and the development of drugs to prevent the onset of such events, etc. Industry-academia collaboration with pharmaceutical companies, test reagent companies, etc. is possible. Graduate School of Biomedical Engineering
KODAMA Tetsuya, Professor
PhD (Engineering), PhD (Medicine)
|
[Skeletal Muscle]
Exercising "Cultured" Myotubes!FeaturesWe succeeded in generating highly developed cultured C2C12 myotubes by manipulating intracellular Ca2+ transients with electric pulse stimulation (EPS), that are endowed with similar properties to in vivo skeletal muscle in terms of (1) excitation-induced contractile activity as a result of de novo sarcomere formation, (2) higher energy expenditure (as assessed by AMPK activation), and (3) improved insulin responsiveness (as assessed by exofacial myc-GLUT4 translocation assay). Targeted Application(s)/IndustryTaking advantage of our “in vitro Exercise Model", our innovation will be an excellent alternative for the animal experimentation that can be applicable for a wide array of skeletal muscle research including drug screen. |
[skin]
Visualization of Biological Microstructure with High Frequency Ultrasound and Photoacoustic ImagingFeatures"Features" Targeted Application(s)/IndustryBiomedical Imaging Laboratory, Graduate School of Biomedical Engineering
SAIJO Yoshifumi, Professor
PhD (Medicine)
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