Tohoku University. Research Profiles

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"S" Keywords - 167 Result(s)

S

 s

[sleep]

Analysis of Biological Signals and Visualization

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Recent development of sensor technology and ICT have enabled collection and acculumation of huge amount and wide variety of biological data. We have been investigating analysis and processing methods of the biological data for supporting clinical diagnosis and health care. For example, development of extraction algorithm of fetal electrocardiogram from maternal abdominal siglnals, and estimation and visualization algorithms of status of autonomic functions based on diverse biological signals.

Targeted Application(s)/Industry

System development of biosignal anaysis, visualization, and diagnosis.
Development of monitoring and evaluation methods of alertness and sleepiness of traffic driver and workers.
Shift work scheduling based on circadian clock.

Graduate School of Information Sciences
NAKAO, Mitsuyuki, Professor Doctor of Engineering

[slip]

Development of Fall-Prevention Footwear Based on Mechanical Analysis of Slip-Related Falls

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The number of fatalities due to falling accidents indoor/outdoor has increased in Japan as well as in other advanced countries. The fatalities due to falling accidents in a year have exceeded those due to traffic accidents in Japan recently. Because more than 80% of the fatalities are elderly people, it is considered an urgent issue to prevent their falling. We have conducted researches on falling during walking due to induced slip, in the contact interface of shoe sole and floor, through tribological and biomechanical approaches. We clarified the required values of static friction coefficient (figure 1), between shoe sole and floor, and how to gait to prevent slipping through kinetic analysis of gait. We also succeeded in the development of a unique footwear outsole having the high-grip property (figure 2) and high slip-resistant concrete pavement blocks (figure 3) through the collaboration with regional companies. We have recently conducted research and development of footwear that is able to prevent falls due to balance loss after slipping.

Targeted Application(s)/Industry

Products for fall prevention in daily life or in work site. Evaluation of slip resistance of footwear and floor materials.

Graduate School of Engineering
YAMAGUCHI, Takeshi, Associate Professor Doctor of Engineering

[small molecule compound]

Innovative anemia therapy: Development of new anemia drugs targeting the novel mechanism of erythropoiesis

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Strong points
Anemia is a very prevalent disease. Nevertheless, an effective therapy is yet to be discovered. Erythropoietin is effective only for those with renal dysfunction. We have found that inhibition of an enzyme for epigenetic regulation results in a prominent increase of erythropoiesis, pointing to a new target for anemia therapy. We have also generated a new, cell-based assay system for the enzymatic activity and carried out small molecule screening.

Collaboration with industry partners
We are seeking a collaboration to accelerate the development of new anemia drugs based on these findings. Together we will advance the development of the candidate molecules currently identified as well as conduct further screening of larger chemical space for better candidates and/or for drug repositioning.

Targeted Application(s)/Industry

Department of Biochemistry, Tohoku University Graduate School of Medicine
IGARASHI, Kazuhiko, Professor Doctor of Medicine

[small-molecule chemical compound]

Drug Development for Fundamental Treatment of Alzheimer's Disease

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Background: Alzheimer's disease (AD) is a neurodegenerative disorder with a large unmet medical need. Recently, our pilot clinical study suggested the possibility that 1-year oral administration of decocted nobiletin-rich Citrus reticulata peel could be of benefit for improving the cognition of patients with AD, with the following pharmacological features: 1) this Kampo medicine includes a large amount of nobiletin that can rescue the memory impairment and prevents hippocampal amyloid beta accumulation in APP-Tg mice, as originally reported by us, and 2) the medicine reversed impaired learning and memory to a greater degree than nobiletin in animal, to which sinensetin, another constituent contributes in large part.
Research plan: We thus try to identify endogenous molecules that can bind selectively to nobiletin and sinensetin in hippocampal neurons, and to further synthesize novel compounds that are capable of more potently improving learning and memory impairment in animals than both natural compounds.

Targeted Application(s)/Industry

Our research goal is discovery of the drugs for fundamental treatment of AD. I hope to conduct collaborative research with a willing company for a practical application of this technology in industry.

Department of Pharmacotherapy, Graduate School of Pharmaceutical Sciences
YAMAKUNI, Tohru, Associate Professor PhD

[social walfare]

Economics of Aging

Features

I investigate on the economics of aging, the optimal social welfare policy, low fertility and so on not based on the historical and systematic approach but based on the neo-classical economic theory. I also use econometric method and statistical approach. I often estimate the future projections of the population, public finance, magnitude of private markets, the results of public policies.
I also research on the comparative studies on East Asia (Japan, China, Korea, Taiwan) and European (especially Scandinavian countries). I provide statistic data and information on the economic and political systems on the aging in Japan.

Targeted Application(s)/Industry

The future estimation on the financial status , market caused by low fertility and aging. The effective management of the medical institutions, social welfare systems, gender equality societies for the central and local government, research institutions, public enterprises, and financial Institutions.

Graduate School of Economics and Managemant
YOSHIDA, Hiroshi, Professor

[sodium flux]

Low-Temperature Synthesis of SiC Porous Bulk by Using Na

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SiC ceramics is generally prepared at high temperature of 1200–2000ºC. We are able to prepare SiC at around 700ºC by using Na. Nano-powder of beta-type SiC was obtained from a mixture of Si and carbon powders in a Na melt. SiC porous ceramics were synthesized by heating mixtures of Si powder and carbon black at 700–900ºC in Na vapor. Biomorphic cellular SiC ceramics were formed by heating carbonized woods at 700 ºC with a Na-Si melt.

Targeted Application(s)/Industry

Applications : SiC porous ceramics are used in a wide range of applications, such as filters for gas or molten metal, diesel particle filters, catalysis supports, and light-weight structural materials.
Industry : Ceramic Engineering

Institute of Multidisciplinary Research for Advanced Materials
YAMANE, Hisanori, Professor Doctor of Science

[soft-X-ray emission spectroscopy]

Nano-Scale Total-Analysis Based on TEM

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Our lab develops accurate nanometer scale characterization methods of crystal structures by convergent-beam electron diffraction (<strong>CBED</strong>) and electronic structures by electron energy-loss spectroscopy (EELS) and soft-X-ray emission spectroscopy (<strong>SXES</strong>) for evaluating new functional materials. For performing crystal structure studies, we developed a new Ω-filter electron microscope and a refinement soft-ware, which can perform not only atom positions but also electrostatic potential and charge distributions. For electronic structure studies, a high-resolution EELS microscope and SXES instruments were developed.

Targeted Application(s)/Industry

Collaborated research of Local structures (symmetry, polarity, lattice defects) by CBED and electronic structures (bandgap, dielectric property and chemical state) by EELS and SXES on semiconductors, metals and dielectric materials are acceptable. Instructions of those analysis methods are also acceptable.

Institute of Multidisciplinary Research for Advanced Materials
TERAUCHI, Masami, Professor Doctor of Science

[software]

INSTRUMENT AND METHOD FOR ANALYZING METABOLIC CONDITION OF LIVING BODY AND RECORDING MEDIUM

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AIMS: The invention is to analyze metabolic condition, especially in oxygen consumption and energy production in the adipose tissues of human (Patent: JP 3848818).
PROBLEM TO BE SOLVED: To provide an instrument and method for analyzing the metabolism condition of a living body which is constructed in such a manner that it can measure the metabolism condition of a living body correctly and easily, and a recording medium.
SOLUTION: A metabolism condition analyzer is provided with an input means for inputting information about the body of a subject, a control means for processing this information and an output means for outputting results of the processing. The information consists of name, age, sex, race, height, weight, bioelectric resistance value and the date and time of measurement. A data file consisting the control means stores evaluation data of a metabolic condition which is previously determined by medical judgment based on a combination of an internal respiration index and oxygen consumption and energy production in adipose tissues. These are computed by calculating the value obtained by subtracting one from a body density calculated from the height, weight of the subject and the bioelectric resistance value and then multiplying the value. Welcome to your investment or co-operation.

Department of Diabetes Technology, Graduate School of Biomedical Engineering
NONOGAKI, Katsunori, Professor MD, PhD

[solar cell]

Development in Semiconductor Materials and Research of their Properties Considering Device Applications Bringing System Evolutions

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1. Development of Distributed Feedback (DFB) Laser Diodes (LD) widely used in optical communications systems realizing a highly information-based society.
2. Nitride semiconductors famous for blue light emitting diodes
(a) Proposal of InGaAlN system considering device applications in 1989
(b) Success in growth of single crystalline InGaN by metalorganic vapor phase epitaxy (MOVPE) in 1989
(c) Prediction of band-gap energy (Eg) of InN much smaller than the reported values in 1989 and its experimental confirmation in 2002
(d) Observation of photoluminescense from InGaN in 1991
(e) Prediction of phase separation in InGaAlN in 1997
We promoted the JST-CREST project "Research on InN Semiconductor Laser Diodes with High Temperature-Stability for Optical Communications Systems".

Targeted Application(s)/Industry

DFB-LD: Fabrication of periodic structure with submicron scale, Epitaxial growth of semiconductor films on the substrate with fine structures, LD fabrication process, device evaluation, and device simulation
Nitride Semiconductors: MOVPE growth, N-polar growth, evaluation of materials, fabrication of light-emitting devices, solar cells, high-power transistors, and high-power transistors

New Industry Creation Hatchery Center
MATSUOKA, Takashi, Professor Doctor of Engineering

 S

[Small-sized Home Appliances Recycling]

A Study on the Proper Waste Management and Urban Mining Project in Asian Countries; International Resources Recycling and Cross-Border Pollution

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The objective of this research is to maximize international resource recycling efficiency through a feasibility assessment of urban mining project in East Asia. It is not only focused on valuable materials but also on less valuable materials like waste plastics. The merit of this approach is its consideration of social, economic and environmental systems in each country.

Targeted Application(s)/Industry

This research is envisioned to support the establishment of resource recycling systems, developing new business models, people-to-people exchange and information sharing.

Graduate School of International Cultural Studies
YU, Jeongsoo, Professor PhD(Urban and Regional Planning)

[Smart Contract]

Blockchain-based Approachs for High Secure P2P-type Decentralized Cloud Storage and Practical Smart Contract for Trading Personal Data

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We are developing a decentralized P2P (Peer to Peer) type cloud storage that realizes innovative level of security by use of surplus storages of P2P nodes with the Blockchain technology. The developed storage can avoid the risk of large-scale information leakage of stored data due to the weakness of the central server. By using our cryptographic currency for rewards and usage fees in the storage, fair storage usage of all users can also be achieved.
In addition, We are developing a unique smart contract technology for practical decentralized trading of personal data among an unspecified number of users.

Targeted Application(s)/Industry

We hope to conduct collaborative researches with companies developing Bitcoin 2.0 type application (e.g. smart contract, Fintech) based on the Blockchain technology, the Internet of Things (IoT) technology, Medical Database for practical use.

Center for Information Technology in Education
SAKAI, Masao, Associate Professor Doctor of Engineering

[Smartphone]

Message Transmission without Cellular Coverage, “Relay-by-Smartphone"

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Our technology provides the necessary method for sending messages even when the physical infrastructure is not available. The technology utilizes common smartphone WiFi functionality to send message in a multi-hop fashion. Thus it is possible to send message to people further away. Our technology has been designed to be based on Delay-Tolerant Networks (DTN), but the technical key idea is the combination of DTN and Mobile Adhoc Network (MANET), which can improve the message delivery in an area with high population density or where mobility are fixed such as evacuation center.

Targeted Application(s)/Industry

This technology can be used to distribute information during emergency situation such as after disaster. In addition, it is possible to provide additional services such as advertisement within shopping areas, distribution of coupons, exchange of information within small group during public events or uses as transceiver during group hiking. There is also possibility of using this technology to provide communications service in developing nations.

Graduate School of Information Sciences
KATO, Nei, Professor Doctor of Engineering

[SNS analysis]

Natural Language Processing for Semantic Analysis of Big Data

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This lab conducts fundamental research for deep natural language processing (NLP) and NLP-oriented information organization such as classification, extraction, and summarization of language information. Our activities also cover a broad range of applied research including NLP-based information and knowledge mining, information credibility analysis, and resilient ICT through the maximal use of Big Data.

Targeted Application(s)/Industry

(i) Analysis of market trend or research trend through intelligent text mining, (ii) Discovery of potential needs and risks from opinions in social media, (iii) Management of knowledge in a company by analyzing internal documents, etc.

Graduate School of Information Sciences
INUI, Kentaro, Professor Doctor of Engineering

[Social Capital]

Nonprofit Organizations and Social Capital

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Nonprofit organizations strive to solve community and social problems and to create new social values. Nonprofit organizations have the role to create citizenship and social capital - trust, norms and networks - in community. Social capital, an invisible and soft capital has increasingly become important to a sustainable management of an organization.
We hope to conduct collaborative research with willing corporations and organizations for measuring social capital at community/organizational levels and for making practical proposals on how to create and utilize social capital with viewpoints of partnership with nonprofit organizations and human resource development.

Graduate School of Economics and Management
NISHIDE, Yuko, Professor Doctor of International Public Policy

[Social Infrastructure monitoring]

[Sodium]

“HYDRIDE" Researches for Energy Applications

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This group is engaged in basic and applied researches of "hydrides" for practical use in hydrogen energy system. The main subject is the exploration of advanced hydrogen storage materials which support hydrogen energy technologies such as fuel cells. Currently, we synthesize a wide variety of novel hydrides composed of lightweight metals with specific nano-structures using advanced techniques for crystal and electronic structure analyses. In addition to the hydrogen storage, we develop the wide research fields related to hydrides, such as fast lithium ionic conductors.

Targeted Application(s)/Industry

Besides the contributions in industrial progress through the material development for future hydrogen energy system and next-generation secondary battery, we positively provide technical assistance to organizations and companies concerned about our findings.

WPI Advanced Institute for Materials Research /Institute for Materials Research
ORIMO, Shin-ichi, Professor

[SOFC ]

Development of Renewable Energy Systems for Sustainable Development Society

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Development of renewable energy systems as well as research on high efficient energy conversion systems is a key technology to solve the global-scale environmental destruction and energy problems. We are working on the research on the advanced technology of renewable energy such as solar energy and hydrogen. Topics of research are two of the following roughly separately. 
(1) Development of highly effective thermal energy systems and energy saving systems by using spectral control of thermal radiation. 
(2) Aiming at the achievement of the hydrogen energy society, we develop new energy conversion devices based on solid state ionics, and perform feasible studies for solid oxide fuel cells (SOFCs) based on mechanics of materials.

Targeted Application(s)/Industry

High temperature solar absorption materials
High effieciency solar-termophotovoltaic (STPV) system
Small power source for mobile electric devices based on micro-SOFC
New energy harvesting devices in harsh environment

Department of Mechanical Systems and Design, Graduate School of Engineering
YUGAMI, Hiroo, Professor Doctor of Engineering

Fuel Cell and Energy Storage Using Ion Conduction in Ceramics

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Solid oxide fuel cell is a highly efficient power generation system operating at high temperatures using ion conducting ceramics. We conduct basic and multi-aspect research on the electrochemical and mechanical behaviors of the materials for further improving the efficiency, cost, and reliability of solid oxide fuel cells. We are also interested in the reverse operation of fuel cells which enables the storage of the electricity from renewable sources into hydrogen or methane, etc.

Targeted Application(s)/Industry

Graduate School of Environmental Studies
KAWADA, Tatsuya, Professor Doctor of Engineering

[Soft rock]

Development of the method of Baby Borehole Hydraulic Fracturing, BABHY

Features

For the effective measurement of the reopening pressure in hydraulic fracturing, it is necessary to use the testing equipment with sufficiently small compliance. This limitation makes it difficult to apply the hydraulic fracturing for the measurement of the maximum stress, because the compliance of conventional equipments is generally so large. Taking account of this situation, we proposed a new concept which allows us to do the in-situ tests of hydraulic fracturing for stress measurement at so deep depths as more than 1 km. We call the concept the Baby Borehole Hydrofracturing, BABHY for short. In order to put the new concept into practice, we developed the BABHY sonde and finally we succeeded to carry out hydraulic fracturing test by using the tools in a vertical borehole of 811 m depth. We hope to conduct collaborative research with a willing company for a practical application of this technology in industry.

Large-Scale Environmental Fluid Dynamics Laboratory, Complex Flow Division, Institute of Fluid Science
ITO, Takatoshi, Professor Doctor of Engineering

[Soil Improvement]

Development of Recycling Technology for High-Water Content Sludge by Using Fiber Materials

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The recycling rate of construction muds and sludge is very low because the water content of these muds is very high and direct reuse of them is very difficult. Therefore, a new recycling technology for high-water content sludge has been developed in this laboratory. This technology is called "Fiber-Cement-Stabilized Soil Method", and it uses fiber materials and cement. The main feature of this method is to mix the fiber materials with the sludge, and the fiber materials included in the soil produce several geotechnical merits.

Targeted Application(s)/Industry

The modified soils produced by this method can be used as ground materials for reinforced embankment of the river bank and soil structures because they have several features such as high failure strength, high failure strain high durability for drying and wetting and high dynamic strength.

Graduate School of Environmental Studies
TAKAHASHI, Hiroshi, Professor Doctor of Engineering